Protein Alignment CG5112 and faah-4

DIOPT Version :10

• Sequence 1: NP_651400.1
• Gene: CG5112 / 43083
• FlyBaseID: FBgn0039341
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_499545.1
• Gene: faah-4 / 176620
• WormBaseID: WBGene00013232
• Length: 647
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 136/560 - (24%)
• Similarity: 232/560 - (41%)
• Gaps: 106/560 - (18%)

  Fly    37 VSGPPSLEQ-QTTITK----SAVELAQQIRERRQRSYDIVKAYCERIESVNRDLNAVVDGPFPEA 96
            |.|..:.|| :||..:    ..:.|...::..:..:|.::.|:..|...||.::|.:.: ...||
 Worm    74 VKGNETAEQIETTFNEILKLDLIALKSALQTDKYNAYTVLCAFVWRAIDVNSEINCITE-VIREA 137

  Fly    97 LDQAREIDRKLDEKEYSDEDLRRLPFLGVPFSTKDSTAVAGRLHTLGLLARKSERSTTDAECVRL 161
            .:.|..:|   |....:.|   :....|:|||.|.:..:.....|:||.....:..||....|:.
 Worm   138 FNTAEALD---DNYAQTGE---KGQLFGLPFSVKSNFYMENYDVTVGLAKLLEQPKTTTCPMVQF 196

  Fly   162 MKESGAIIIATSNVPEVNKWIESRNMLIGCTNNPYDLRRSVGGSSGGEAALIAACCTGFGLGTDI 226
            :.:.||:....:|||:......|.|.:.|.|.||:|..|:.||||||||||:||....||:|:|:
 Worm   197 LSDQGAVPFCLTNVPQGLLSYVSSNPIYGTTKNPWDFSRTPGGSSGGEAALLAAGGAAFGIGSDL 261

  Fly   227 GGSIRIPAFNCGIFGHKPTS---------------GAVNMA-GCTFRTGKEKDTMVCAGPMSRSA 275
            .||:||||..||:...|||.               |.:.:: |...|:.||::.::.........
 Worm   262 AGSLRIPAAFCGLVTLKPTQDRLCVTDTHGGLPGRGRLGLSFGFYTRSVKEQEFLLGLIVGRSEY 326

  Fly   276 RDLLPMMQVLVEPSLKAKLKLDQKVDLKRLRYFYVSSNGMAQCNPINRETERVMYKIRKHFEAVS 340
            .:|.||       |..|||:...:.|.|.:..::|...    .||:.....|.:.:..|..:|..
 Worm   327 LELCPM-------SSPAKLEKHIEKDQKLVIGWFVDDG----FNPVVPSNRRAVEETVKSLQAKG 380

  Fly   341 GK--DVRHADL----PYTKLTGKMWRYWMTQEPANFNLLLGNGAELNPFVELFKKILGQSDYSMA 399
            .:  :::.||:    |...:...::|..|....|..:.:.. |.:.:..::||.:::......:.
 Worm   381 HQVVELKLADVSEEFPPFAVADMLFRNVMPDNGAYMSEMYA-GEQYDEHMKLFIRLVCLKQNFLV 444

  Fly   400 AI---YGLIDSVLPKEKEKLMREAT----------AKCKKSVQ--DLLGDDGVLFFHSSPRTA-- 447
            :.   ||    |:|..|..|.:...          |.|:::.:  |......:.::.|....|
 Worm   445 SFLLRYG----VMPFAKLALSKRLACIGSAYNSDLAACRQNQENTDSYKLQWIRYWKSKKIDALI 505

  Fly   448 ---------PFHYYPLVKFNDFAYFSLFNVLHLPATQVPMG----------LD------------ 481
                     ||. ||....|......|||:|.:||..||:.          :|
 Worm   506 CPSFITPAQPFE-YPAQLSNGAFITGLFNMLDVPAGVVPVSPVNQKDVDQLIDGFSTEGDLLLKK 569

  Fly   482 -------SKGMPLGIQVVANPNNDRLCLAVAEELERTFGG 514
                   :.|:|..:|||..||.:.:||.|...:|.:..|
 Worm   570 QREAARGTTGLPNAVQVVTLPNCEEMCLRVMRLVEESAEG 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5112	NP_651400.1	GatA	50..520	CDD:439924	130/546 (24%)
faah-4	NP_499545.1	Amidase	112..597	CDD:450241	123/508 (24%)