Protein Alignment rha and cep120

DIOPT Version :10

• Sequence 1: NP_651390.2
• Gene: rha / 43071
• FlyBaseID: FBgn0027376
• Length: 1332
• Species: Drosophila melanogaster
• Sequence 2: XP_031751459.1
• Gene: cep120 / 100145455
• XenbaseID: XB-GENE-5872143
• Length: 996
• Species: Xenopus tropicalis
• Alignment Length: 1362
• Identity: 234/1362 - (17%)
• Similarity: 432/1362 - (31%)
• Gaps: 500/1362 - (36%)

  Fly    30 SDQVYCVLLHVVEAINFIGRDATDRQQIVMNAALNSVDFEVEGTQSEETIIFNSNCIWECDLAGI 94
            |||:  :::.::|..:|..|   .|..:|::|..:......:.....|...|.:...||.|...:
 Frog     5 SDQL--IVVSILEGRHFPKR---SRHMLVVDAKFDGEQLSTDPVPHLEQPQFATELAWELDRKTL 64

  Fly    95 KRLKTDHRPVKMTFYACRGGGAERKTIGTLLLPVRGLPVLGTVGSHNSPHLKMFWHKLICTSSEF 159
            .:.:....|:|:..:|.....:.::::|.::|.:|     .......:|.    |:.|:  ||::
 Frog    65 HQHRLQRTPIKLQCFALDTLTSAKESVGYVVLDLR-----AAQEKKQAPK----WYSLL--SSKY 118

  Fly   160 RSHKPEVLLMLTIIKKSILHTKDFEHFMQFTEVKSPPTPPMQS--PGHSITASMLQSQANVYVQS 222
            ...|||:.|.:::         :.::.......|:...||.:|  ||         ..|.:..:|
 Frog   119 TKFKPEIQLNISL---------ETDNKPAVDTFKAKEAPPRRSKVPG---------DLAGLEPKS 165

  Fly   223 LVQL-----GLLQVG-----NDPLVDCDIIEVVLQLKQLRNVTGLVKSLNQGKPPSSVILVFDFV 277
            ||.:     |..|:|     .|..|....|....||:||     :..:|...:|.......:..:
 Frog   166 LVPILNEAEGYHQIGPAEYCKDYFVLSVTIAFATQLEQL-----IPSTLRLPEPQPEFFFYYSLL 225

  Fly   278 GN-VTNIELKLNESDTYTLN-----DVLGLRFKTSLRSMRLYFQRIFYLPINMYMNGTAIAHYRM 336
            || ||      ||..|..:|     :...:|.::|...:.:|......|.|::.....::....:
 Frog   226 GNDVT------NEPFTDLINPEFEPERASVRIRSSKEVLCMYLSVQPKLQIHLCCGDQSLGSTDI 284

  Fly   337 DFTNLLPADDFFSDNRKYTSNGSFSFNRFGRTDSGREPKPPLMEYTF--SVDLKTIFSRQEQEEP 399
            ..|.||.......::......|:|......|........|..|..|.  |:.|:.....|....|
 Frog   285 ALTGLLNKASVEIEHHPVVVEGAFILTPPNRAKQNLSAVPLEMSPTIGVSIALQKEIGLQSVHHP 349

  Fly   400 ERTPSIASGNLDSEDEQYLGQTFCASVVRSRLNLNESEETDEIASNVMKQLANDSETEVIEMKSN 464
            :..|                               :|...:|:.:..:|:.||..|
 Frog   350 KEQP-------------------------------QSVAAEEVPTTPLKKSANLKE--------- 374

  Fly   465 TKNSKHNTSPQRKSQESKKLIRESSRNTRNSLENLQNVDELTSLDLFELEEKRQEKIAELERIKA 529
                     ..|.....|.|:...|..|:         ||.|.              :|.|.||
 Frog   375 ---------GARSPPPPKPLMFSDSPPTK---------DEATE--------------SEAESIK- 406

  Fly   530 GQSESLLQTELKVKKHKKADLELQGKKSQLETINEVPPKSLRKSKPVSQSELNNVPKIQENLPIL 594
                |..|.|..:.|                      |.:..||.|:|:..|:
 Frog   407 ----SDFQAEPPLSK----------------------PLTRSKSPPLSEPPLS------------ 433

  Fly   595 NNQTKGSRIQKENCEENNEDLS-YALSEEHSSSNEKLDKKPGA-----SKTMRPPEHVDTDLETD 653
                 ||     :|....:.:| .|.:...|||.:|:...|.|     :..:|...:||.....:
 Frog   434 -----GS-----HCPTPIQGVSAIAKNTSESSSAQKITVPPAAHHFCFTIDLRSIRNVDVGFPVN 488

  Fly   654 ISVFSIQKKRKSKSKLVISNELHNFEDSSTDTLEKGRPNPSKGDLKLRARWVEVNKVQTQALIET 718
                            .|....:.|..|:...:    .||.          |||.|       ..
 Frog   489 ----------------CILRYSYPFFGSAAPIM----TNPP----------VEVQK-------NM 516

  Fly   719 EKFL-QKTCPAELDEVLYEDQVALGQAKTSKPTKRKVKKPEEDKVKRIDYETSYEEEITFCHPEK 782
            |.|| |..|..:...:.::.|                     |...|:..      .:...|  |
 Frog   517 EVFLPQSYCAFDFATLPHQIQ---------------------DTFLRLPL------LVELWH--K 552

  Fly   783 DPMT---MIGENPINLNDLASSEEYISISEGNSKPAEIVYTETEQRVTFVNPKRDREKKKLSSLS 844
            |.||   :||...|.|:::.|||                      :..|:.|
 Frog   553 DKMTKDLLIGVTKIQLSNVLSSE----------------------KTRFLGP------------- 582

  Fly   845 KDDLLVEVRSEEYINLRSSARSKTDCVRKKKKISIHEDQVYQAELTPSEEPSSQSESRGTDNANP 909
                                               |.||.:
 Frog   583 -----------------------------------HGDQCW------------------------ 588

  Fly   910 ITDQPQVDRVKKKKRDTSGDQQLFHVEYTSSQKSISKTEGNVKCKELIEPDVEQTDVQVLKKKKL 974
                                :|.|     |.:.:::..||:                   |.|..
 Frog   589 --------------------RQTF-----SERITVTAVEGS-------------------KNKVA 609

  Fly   975 KKTLVTNDTVAQDYETLEEETIKPVKKKIVRKKSSVILEKIEDTENKGPADEVVSVEAKKIIKKK 1039
            :.:.:.         |||:..:..|::.:|.          |.:::.|.             :|.
 Frog   610 ELSYII---------TLEDYGLVKVREVVVS----------ESSQSTGQ-------------EKG 642

  Fly  1040 AKPACDNPTVEEYPKTKKGESRKLKSTSKEHFTMEKPSSTID-SIGQKIKSWRRQQIDLFEQELA 1103
            :.||                 :.|:||:    .:.:|..|:: ....:::.|:..|.|||..:|.
 Frog   643 SLPA-----------------QTLQSTA----PLPEPRETLEYKAALELEMWKEMQEDLFVNQLK 686

  Fly  1104 RKEMHYIKQLEQ----------------------MESQ-EARLHQLHKADTNL--DETFISKIPN 1143
            :||:.:::.|.:                      :|.| :..|..|.|.:..|  ||..:.|:..
 Frog   687 KKELVHMQALAEEWKRRDKEREALVKKKVAEYTVLEEQLQKALADLEKRERQLANDEMELKKLKA 751

  Fly  1144 VSEVDYEAKFTELEEHIALLKSEMEEQVRLFENRSRELRQENLQLYSEKTELKVRIAALEQQIGD 1208
            ..::|.|....|.::.|..::.:...|:.|..:::::|.::.|:|..:..|.:.::..:|::...
 Frog   752 QLQLDCERSIQERQDSIRRVREDCMHQIELERSKAKQLEEDKLRLQQQLQEAEHKVKLMEKEFLQ 816

  Fly  1209 LKAQGSDEGDLKEVLGELRSQHYRYNNLAREKEL-------FRKRWRRSAKRVHALKLAMYERSL 1266
            .|.|.|.:.::: :..::.........|.|:.||       ::::|.|:.|.:..||....|.::
 Frog   817 YKEQQSSKPEIR-LQSDINLLTLEKVELERKLELTTKSKLHYKQQWGRALKELARLKQREQENAM 880

  Fly  1267 ER--------EHSNIR---VEPIDLRKILTKDAEEFEREYGQFRQ--NGMSPRYTLNSLSGS 1315
            .|        ||..:|   .|..|:.|...::.||...|..:.||  :...|..|..:.:||
 Frog   881 ARLKKQQQELEHMRLRYLAAEEKDVVKTERQELEEIRNELNRLRQQEDRKQPPDTSANANGS 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rha	NP_651390.2	DUF3668	158..387	CDD:463569	49/248 (20%)
		PTZ00108	<473..775	CDD:240271	53/308 (17%)
		COG4913	<1092..>1307	CDD:443941	54/259 (21%)
cep120	XP_031751459.1	DUF3668	117..339	CDD:463569	50/250 (20%)
		C2	<521..>587	CDD:472691	21/164 (13%)
		Smc	<694..>932	CDD:440809	46/238 (19%)