Protein Alignment Nepl16 and Ecel1

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_063123735.1
• Gene: Ecel1 / 60417
• RGDID: 61806
• Length: 792
• Species: Rattus norvegicus
• Alignment Length: 705
• Identity: 142/705 - (20%)
• Similarity: 241/705 - (34%)
• Gaps: 197/705 - (27%)

  Fly   150 SAPPECSDPICEA-VASSIQARLNWNKDPCTEFKKFSC--W---RNTPNKNIT--NLIEMGNSQK 206
            :.|..|.:....| .|..:.|.|:.:.|||.:|..|:|  |   ...|:..:|  .:..:|..
  Rat    95 ACPEGCPERKAFARAARFLSANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQ-- 157

  Fly   207 SVDSQMLYLFQNKIMNGSFGI----LHNLFESCLQ----QTTNSTVMHRIFDSLGG--------- 254
              :.:.|.....:...|..|.    :...|.|||.    :......|..:.:..||
  Rat   158 --NEERLRRLLARPTGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAADR 220

  Fly   255 ------------YLPVGSVGPSSIAPLIAKIYDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSS 307
                        |...|....:::..|...:.|...|..| :..|......|...|.::....|.
  Rat   221 PGAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYV-IRIDQDGLTLPERTLYLAQDEESE 284

  Fly   308 TIL-------ERKIRWMSPKAPPSRIRQGVPKLLADLIENFLPYFVSYAQR-----VSEKDTIFE 360
            .:|       ||.:|.:.                ||.:|......:...||     |||.|
  Rat   285 KVLAAYKVFMERLLRLLG----------------ADAVEQKAQEILQLEQRLANISVSEYD---- 329

  Fly   361 FIKDLNKLQVEHSRRGFWDSTVLYN---VSSLQDLYPVLNWTLLIPQ------NWSGPIVVRNSD 416
               ||.:           |.:.:||   :..||.:.|.|.|..|:.|      :....:|:..:|
  Rat   330 ---DLRR-----------DVSSVYNKVTLGQLQKITPHLQWKWLLDQIFQEDFSEEEEVVLLATD 380

  Fly   417 YLKALEYFLTKYPTRVAHNSL-----LLLS---------ALQILPR-----DYPS--PEVCTRST 460
            |::.:...:...|.|:.||.|     ::||         ||..|.:     |.|.  ..||....
  Rat   381 YMQQVSQLIRSTPRRILHNYLVWRVVVVLSEHLSPPFREALHELAKEMEGNDKPQELARVCLGQA 445

  Fly   461 MWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKAHL-KRAPSL-------KGAALVKLSALK 517
            .........:|::.:|.|...|   .:.:.:.:.:|..| :|...|       |.||..||..:.
  Rat   446 NRHFGMALGALFVHEHFSAASK---AKVQQLVEDIKYILGQRLEELDWMDAQTKAAARAKLQYMM 507

  Fly   518 IQSQTWEGFSNTTDLLKSLQPLNITSECWFQNILEIYKKNKLEPNDISLNGG--------SHDAW 574
            :.    .|:   .|.|  |:|..:..|..|:...:.|.||.|.....|:...        ....|
  Rat   508 VM----VGY---PDFL--LKPEAVDKEYEFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTW 563

  Fly   575 AYPIVS-TIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKSFDE---- 634
            ..|..: ..:|....:.:|.|..::....::...|..|:|..:|..|..|    :|..:|:
  Rat   564 LLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHE----LTHGYDDWGGQ 624

  Fly   635 ---------------------KAMRCVPHSVNIFSNYSRM--------DILIHSGGMQISYHSML 670
                                 || .|:....:.|:.|::.        :.:...||::::|::..
  Rat   625 YDRSGNLLHWWTEASYSRFLHKA-ECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYYAYQ 688

  Fly   671 SLT---GPIKGMARLPGLNLTPTQIFFLVSAQELC----AESNYLGI--DTNAPE 716
            ...   ||...:.|   |..|..|:||:..||..|    ::|.||.:  |.:|||
  Rat   689 KWVREHGPEHPLHR---LKYTHNQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPE 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	136/678 (20%)
Ecel1	XP_063123735.1	None