Protein Alignment: Nepl16 and PHEX

• Sequence 1: NP_001097912.1
• Gene: Nepl16
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_000435.3
• Gene: PHEX
• HGNCID: 8918
• Length: 749
• Species: Homo sapiens
• Alignment Length: 795
• Identity: 151/796 (19%)
• Similarity: 270/796 (34%)
• Gaps: 253/796 (32%)

  Fly   118 LVASPILFLISTAPSPLPRDCYMDGDRCSPAVSAPPE-CSDPICEAVASSIQARLNWNKDPCTEF 181
            ||...||||:|.....|               .|..| |..|.|...|::|.:::|.:.|||..|
Human    31 LVLGTILFLVSQGLLSL---------------QAKQEYCLKPECIEAAAAILSKVNLSVDPCDNF 80

  Fly   182 KKFSC--------------------W-RNTPNKNITNLIEMGNSQKSVDSQMLYLFQNKIMNGSF 225
            .:|:|                    | |:..:..:..|:|...|::. |::.:.  :.||:..|.
Human    81 FRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRR-DTEAIQ--KAKILYSSC 142

  Fly   226 GILHNLFESCLQQTTNSTVMHRIFDSLGGYLPV--GSVGPSSIAPLIAKIYDLGPSPLVDLYHDL 288
                 :.|..:::.....::|.:..|...: ||  .::||..:
Human   143 -----MNEKAIEKADAKPLLHILRHSPFRW-PVLESNIGPEGV---------------------- 179

  Fly   289 SYGRRPHILL----IISGPSTSSTILERKIRWMSPKAPPS-----RIRQGVPKLLA--DLIENFL 342
             :..|...||    ...|..::|..:.   .::||....|     ::.|....|..  |.::|
Human   180 -WSERKFSLLQTLATFRGQYSNSVFIR---LYVSPDDKASNEHILKLDQATLSLAVREDYLDN-- 238

  Fly   343 PYFVSYAQRVSEKDTIFEFIKD-------------------------LNKLQVEHSRRGFWDSTV 382
                 ..:..|.:|.:::|:.|                         :.::.:.|..|   .|..
Human   239 -----STEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENR---TSEA 295

  Fly   383 LY---NVSSLQDLYPVLNW---------TLLIPQ----NWSGPIVVRNSDYLKALEYFLTKYPTR 431
            :|   |:|.|..:.|..:|         |.|.|.    :.|..:|||...|.|.|...|.....:
Human   296 MYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKK 360

  Fly   432 VAHNSL---LLLSALQILPRDY------------------PSPEVCTRSTMWALPELSSSLYIAQ 475
            ...|.|   ::.|.:..|.|.:                  |..:.|......|||.:...:::..
Human   361 TIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDV 425

  Fly   476 HSSEDLKDTTKR---------AEIIFKS---LKAHLKRAPSLKG-AALVKLSALKIQSQTWEGFS 527
            :..||.|:..:.         .:::.|.   :.|..||....|. |.|.|:...       |...
Human   426 YFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYP-------EFIM 483

  Fly   528 NTTDLLKSLQPLNITSECWFQNILEIYK---------KNKLEPNDISLNGGSHDAWAYPIVSTIF 583
            |.|.:.:.|:.:..:...:|.|:|:..|         ..|..|..        :.:..|.....|
Human   484 NDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKT--------EWFTNPTTVNAF 540

  Fly   584 YDTLSHSIVVPLSVILIPYF-NAVLPPYLHYASVGVSIAKEILRSI------------------T 629
            |...::.|..|...:..|:| ....|..|.|.::||.:..|.....                  |
Human   541 YSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWST 605

  Fly   630 KS---FDEKAMRCVPHSVNIFSNY----SRMDI---------LIHSGGMQISYHS--------ML 670
            :|   |.||. :|:   :|.:|||    :.:::         :..:||::.::.:        ..
Human   606 ESEEKFKEKT-KCM---INQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQ 666

  Fly   671 SLTGPIKGMARLPGLNLTPTQIFFLVSAQELC------AESNYLGIDTNAPEFDNILGWLVAQGG 729
            .|..|:     |||:..|..|:|||..|...|      |....:.|..::|....:.| .::...
Human   667 GLEEPL-----LPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNG-AISNFE 725

  Fly   730 SATEVFKCPSGSMIN 744
            ...:.|.||..|.:|
Human   726 EFQKAFNCPPNSTMN 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	135/737 (18%)
PHEX	NP_000435.3	M13	74..747	CDD:189000	135/738 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000