Protein Alignment Nepl16 and Nepl11

DIOPT Version :9

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 128/688 - (18%)
• Similarity: 231/688 - (33%)
• Gaps: 230/688 - (33%)

  Fly   166 SIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQ-----KSVDSQMLYLFQNKIMNGSF 225
            :::..|:.:|.||.:|..:.|      .:..||.|.|..:     |..|...|...:.:::
  Fly    34 NLEPYLDTSKQPCQDFYGYVC------SHSANLSETGRQRFQSLLKETDVAQLMDMELQLI---- 88

  Fly   226 GILHNLFESC-----LQQTTNSTVMHRIFDSLGGYLPVGSVGPSSI------------APLIAKI 273
                |.|:||     ::....|    :::...||:   .|:.|:.:            ..|:...
  Fly    89 ----NFFKSCESGRGVEALKGS----QLYRQSGGW---PSLEPNKVNASQRTNQTQRWLGLLGYF 142

  Fly   274 YDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLLADLI 338
            :::|.....:....:...:|   |:::....|....|.:
  Fly   143 HEVGAPYFFETSVTMQSNKR---LVVLQPDGTRRNTLRK-------------------------- 178

  Fly   339 ENFLPYFVSYAQRVSEKDTIF------EFIKDLNKLQVEHSRR----------------GFWDST 381
                     :.|||.|....|      ..:..|..|.:|.|||                |.:...
  Fly   179 ---------FEQRVGEVLQSFGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRI 234

  Fly   382 VLYNVSSLQDLYPVLNW-----TLL---IPQNWSGPIVVRNSDYLKALEYFLTKYPTRVAHNSLL 438
            |..|.|.::     |:|     .||   .||. |..|||:....|  :|||     ..:.:.|::
  Fly   235 VFGNASLIR-----LDWDGYFRKLLGGKTPQA-SDTIVVKQLPRL--VEYF-----ALLQNTSMV 286

  Fly   439 LLSALQILPRDYPSPEV---CTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEI--IFKSL-KA 497
            .|  |..:..||....|   |.:.:.....:|.:  ::.|      :.|..|.|:  ::..| ||
  Fly   287 RL--LNWIWTDYLMDIVDADCHQLSETYAGDLYA--HVVQ------RVTANRVELAQMYSELGKA 341

  Fly   498 HLKRAPSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQNIL----EIYKK-N 557
            :   ...|.|:..:...:.:...|......:||  |...:.|:..    :.:||    .:|:. .
  Fly   342 Y---TDQLGGSVWIDEISRQSSRQFLGNIMHTT--LNGDERLDAA----YHSILLGRRSLYRNLE 397

  Fly   558 KLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAK 622
            ||.....:....||.|......:.:|         .|::..|..: |...|  |:|..:|...::
  Fly   398 KLRKFQRTRRLASHSAQQVRRYAQMF---------APVNAFLGQH-NLSTP--LNYLLLGEFFSR 450

  Fly   623 EILRSITKSFDEKAMR-------------CVPHSVNIFSNYSRMDILIHSGGMQISYHSMLSLTG 674
            .::.:.:.|..:.|.|             ||....|      .:|:|:    ..::....||..|
  Fly   451 SLVAAGSSSRTQGAWRSSDSERRFAIFQQCVGKQTN------AIDLLL----SLLAQRQALSAYG 505

  Fly   675 PIKGMARLPGL-------------NLTPTQIFFLVSAQELC-AESNYLGID----------TNAP 715
              :.:|...||             .::..::||:.|....| :|...|..|          .|:|
  Fly   506 --QWLATQAGLVERVDAVLAAGSSKMSLQRLFFVTSLLVDCRSELGALQQDRKRQVTHATLRNSP 568

  Fly   716 EFDNILGWLVAQGGSATEVFKCPSGSMINVQ-KTCNVL 752
            ||              .|.|:|..|.::..| :.||.|
  Fly   569 EF--------------LEAFRCRPGDVLYPQDQRCNPL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	123/673 (18%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	123/672 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910