Protein Alignment Nepl16 and Nepl9

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 716
• Identity: 140/716 - (19%)
• Similarity: 224/716 - (31%)
• Gaps: 269/716 - (37%)

  Fly   172 NWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSVDSQMLYLFQNK-IMN------GSF---- 225
            |.:.|||.:|...:|..          .:....:.|.|....||:..: .||      |:|
  Fly    58 NDSMDPCDDFYAHACGN----------FDQTKEENSDDFLPPYLYNKQDRMNFFTAEVGNFETIP 112

  Fly   226 -GILHNLFESCLQQ------TTNSTVMH--RIFDS---LGGYLPVGSVGP--------------- 263
             .::..|:..|.::      |......|  |:.|.   |..:..|.|..|
  Fly   113 GRLISQLYTECRKREERNVFTPTRLTSHWERMLDEIPFLARHKEVLSSWPFLKHQWERRRLYGQL 177

  Fly   264 ------SSIA----PLIAKIY----DLGPSPLVDL-----------YHDLSYGRRPHILLIISGP 303
                  :.:|    |.:..||    .:..||:.:|           ..|:..||...:..||
  Fly   178 NWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEELPCPSIADFQSSLSDVLEGRHHQVSRII--- 239

  Fly   304 STSSTILERK-------IRWMSPKAPPSRIRQGVPKLLADLIENFLPYFVSY--AQRVSEKDTI- 358
            |....:|.|:       :|.:|.....:..|.|..:||.|  ||.:.||..|  |...||:..:
  Fly   240 SHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLD--ENTMDYFQQYFAALNFSEERLVG 302

  Fly   359 -FEFIKDLNKLQVEHSRRGFWDSTVLYNVSSLQDLYPVLNWTLLIPQNWSGPIVVRNSDYLKALE 422
             .:|..|:.|                                  |.|.|.   |:|:::
  Fly   303 ARKFPLDVEK----------------------------------ITQAWE---VLRHTE------ 324

  Fly   423 YFLTKYPTRVAHNSLLLLSALQILPRDYPSPEVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKR 487
                   ||:.:|.::..:..|:   .||.   |.|.:    .|....|:........|:....|
  Fly   325 -------TRIVYNYVMWQAREQL---RYPD---CYRVS----EEFERLLHAEYWQWHVLRRHLSR 372

  Fly   488 AEIIFKSLKAHLKRAPSLKGAALVK----------------LSALKIQSQTWEGFSNTTDLLKSL 536
             |:...|.:.|..|...|:.:.|.:                |...:|.....|.:.|.|:|.::.
  Fly   373 -EVALASYQLHTTRFQKLRRSKLSRRDWYGHLWPASVEKKELQVARILQNHAENYLNITELNENY 436

  Fly   537 QPLNITSECWFQNILEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPL------ 595
            :.|.:....::.|:|.:.:..                             |.||.|.|.
  Fly   437 EGLKLEKNSFYANLLILRRAQ-----------------------------LRHSFVSPYVDEEDV 472

  Fly   596 ---SVILIPYFNAVL-----PPYLHYASVGVSIAKEILRSITKSFDEKAMRCVPHSVNIFSNYSR 652
               :..|..:.:.||     |.|.:||:.|:.:.:|....:.......||.|:..  ..|.:|..
  Fly   473 NQPAYFLRHFLHFVLLSLHRPTYHYYATHGLELWRESRLLLDTDGHYTAMDCLER--QSFQHYDA 535

  Fly   653 MDILIHS--GGMQIS---------------YHSMLSLTGPIKGMAR---LPGLNLTPTQIFFLVS 697
            ....|:.  |..:|:               ||..|.  |.....|.   |....|.|.::.|...
  Fly   536 KLAPIYRPLGSHEIAEIFQFYRSFQYSLTDYHFWLQ--GERFAFAETFVLDYFGLNPHRVLFYAV 598

  Fly   698 AQELC--------AESN--YLGIDTNAPEFDNILGWLVAQGGSATEVFKC--------PSGSMIN 744
            ||:||        |:.|  |:    |.|||.              |.|||        ||..|||
  Fly   599 AQQLCNRQTEIFAAQLNRGYM----NLPEFQ--------------EAFKCGAEKAMNPPSRCMIN 645

  Fly   745 V 745
            :
  Fly   646 M 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	139/712 (20%)
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	136/706 (19%)