Protein Alignment Nepl16 and Nepl5

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 703
• Identity: 127/703 - (18%)
• Similarity: 244/703 - (34%)
• Gaps: 223/703 - (31%)

  Fly   144 RCSPAVSAPPECSDPICEAVASSIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSV 208
            |.:|...........:.|.:|..:|:.::....||..|.:::|               ||.|...
  Fly    17 RTTPTACRQTNAPQSVQEMLAEQLQSYMDTKARPCENFYQYAC---------------GNWQIQQ 66

  Fly   209 DSQMLYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIAKI 273
            ..|                 |:|.:   :..|.....::     |..||..::|
  Fly    67 QEQ-----------------HSLRD---RDWTRDRQRYQ-----GQMLPTDTLG----------- 95

  Fly   274 YDLGPSPLVDLYHDLSYGRRPHILLIISGPS---TSSTILE------RKIRWMSP--------KA 321
                   |:|  |  |..|:..:||.....|   :.|:|||      |..:.:.|        ..
  Fly    96 -------LID--H--SVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYNLKKYLQLL 149

  Fly   322 PPS------------------------RIR-QGVPKLLADLIENFLP-------YFVSYAQRVSE 354
            |||                        |:| .|:..:|  |.|..||       |.: |..:.|.
  Fly   150 PPSNSTQWPSVGRGWRPERFDWITTLGRLRLHGLNGVL--LREEVLPRWDDSRNYSI-YVNKPSR 211

  Fly   355 KDT-------IFEFIKDLNKL---------QVEHSRRGFWDSTVLYNVSSLQD------------ 391
            ::|       :.|.:.|:.:.         ||:...|      .|:.:..|:|
  Fly   212 QETQPMGEGAMIELLLDIGQTKRTANALARQVDDFER------KLHRLQELEDDEGPREMQLGYL 270

  Fly   392 --LYPVLNWTLLIPQ-------NWSGPIVVRNSDYLKALEYFL-TKYPTRVAHNSLLLLSALQIL 446
              ..|.|.|...:.|       :....:::.|..||:||...: ::.|..|.  |.::|..|..|
  Fly   271 DSYLPQLRWLSFMRQVRIDSELDLRSTLIIENIPYLRALSDLMESESPDTVC--SYIMLKWLAFL 333

  Fly   447 PRDYP---SPEVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKA---------HL 499
            .:..|   |...|..:...|:| |:||..:.|..|:  .::......:|:.||.         .:
  Fly   334 KQQGPADISRGECVAALRRAMP-LASSWLVGQQFSD--PESESYVSSLFQRLKVRFGQILAENRM 395

  Fly   500 KRAPSLKGAALVKLSALKIQSQTWEGFSNTTDLLKSLQ---PLNITSECWFQNILEIYKKNKLEP 561
            :.:|.|......||.|:::|.    ||..|.::....|   .::::...::.|.| :..:.::|.
  Fly   396 RLSPPLVHILQQKLRAVRLQM----GFFQTEEIEDVEQYHVRIDLSGHSFYGNQL-VLLRQRVEA 455

  Fly   562 N---------DISLNGGSH-----DAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLH 612
            |         :.:.:.||:     ::|.....|.: |....:.::||..::.:|.::..:.....
  Fly   456 NHDLLYINVTNFANSTGSNLSYLSESWEASNSSPL-YVRPRNLVLVPHGLLQLPIWHRNISALQQ 519

  Fly   613 YASVGVSIAKEILRS---ITKSFD------------------EKAMRCVPHSVNIFSNYSRMDIL 656
            :|.:|..:|.|:...   :...:|                  .:.::|:...:...|.:.. :.|
  Fly   520 HAVMGFVLAHELAHGFDMLGMDYDAMGNIMGPVEEIGASRQFRQGLQCLQQQMATGSKWID-EKL 583

  Fly   657 IHSGGMQISYHSMLSLTGPIKGMARLPGL-NLTPTQIFFLVSAQELCAESNYL 708
            .....::::|.:...:..  |...|.|.| ..:..|:||:..||..|..:..|
  Fly   584 ADFVALRLAYETFFGVRD--KREPRDPLLPQFSQRQLFFITFAQFFCGRTPVL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	122/671 (18%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	122/672 (18%)