Protein Alignment Nepl16 and Nep6

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_572831.2
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 724
• Identity: 142/724 - (19%)
• Similarity: 247/724 - (34%)
• Gaps: 226/724 - (31%)

  Fly   162 AVASSIQARLNWNKD----PCTEFKKFSC--WRNTPNKNI---------------TNLIEMGNSQ 205
            |.|...|.:|:.:.|    ||..|.:::|  |.:..::.|               ..||......
  Fly    23 AAAQDCQQQLDNDTDAEVKPCENFHQYACGNWYSNTSQRILGAHDMRSKWVANLKLQLIRYLEES 87

  Fly   206 KSVDSQMLYLFQNKIMNGSFGILHNLFESCLQQ----TTNSTVMHR--------------IFDSL 252
            .|.||    ...|..:..|...|..|:..||..    .|.:..:.|              .||.:
  Fly    88 SSTDS----FSANTSVTTSTAQLGTLYRCCLLSGQSIRTYTDALSRSGANFPLLANHTGGSFDWV 148

  Fly   253 GGYLPVGSVGPSSIAPLIAK---------IYDLGPSPLVDL------YHDLSYGRRPHILLIISG 302
            .....:.:.|...:..|:.|         |:.:.| |..||      .::..|.|...|||:..|
  Fly   149 LANAALRTYGAQGLWRLLVKDNWQSADQRIFYMLP-PKFDLLGRDDELNEFLYQRYLKILLLELG 212

  Fly   303 PSTSSTIL--------ERKIRWMSPKAPPSRIRQGVPKLLADLIENFLP------YFVSYAQRVS 353
            .......|        |:.::.:.|......:....|:.|.|| |:.||      ||
  Fly   213 LRVRRAALLAEKLVAFEKSLQKLLPNDAEQTLVLRKPQSLKDL-ESQLPRLELKRYF-------- 268

  Fly   354 EKDTIFEFIKDLNKLQVEHSRRGFWDSTVLYNVSSLQDLYPVLNWTLLIPQNWSGPIVVRNSDYL 418
              :||.|.|.              |||..|..|:.|..|..:..   |:.::.|.|:|:.....|
  Fly   269 --ETILEGID--------------WDSKTLLLVADLDYLQGLQR---LLAEHTSDPMVLSTWLLL 314

  Fly   419 KALEYFLTKYPTRVAHNSLLLLS----ALQILPRDYPSPEVCTRSTMWALPELSSSLYIAQHSSE 479
            :...||..:     .|:...|.:    .|:.|.:..|.          .|..|...|.:.: |.:
  Fly   315 QLPAYFELR-----LHDDDKLGNQRNHCLEQLRKLMPG----------QLGRLQMQLVLGE-SYQ 363

  Fly   480 DLKDTT-KRAEIIFKSLKAHLKRAPS----------LKGAALVKLSALKIQSQTWEGFSNTTDLL 533
            |:.||. ::..::|:.||...:...:          .:..|..||.|:::             |.
  Fly   364 DVYDTAIQQIAVLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRL-------------LT 415

  Fly   534 KSLQ-PLN-------ITSECWFQNILEI-YKKNKLEPNDISLNGGSHDAWAYPIVS--------T 581
            ..|| |:|       :...| ..|:|:: ..:.|||...:         :..|:.|        .
  Fly   416 PRLQDPINGGPGTPQLGGNC-DANLLQLSLSQAKLEYRQV---------FGEPVTSVPADPLSVN 470

  Fly   582 IFYDTLSHSIVVPLSVILIPYF----------NAVLPPYLHYASVGVSIAKEILRSITKSFDEKA 636
            .:|....:.|.:||.::..|..          .|.|.     |.:|..:|.|::.    :||...
  Fly   471 AYYRLKLNRIELPLGLMATPLIQQQCSKEADTRAKLS-----AGLGYILAHEMVH----AFDLDG 526

  Fly   637 MRCVPHSVNIFSNYSRMDIL---IHSG---GMQISYHSMLSLTGPIKGMARLPGLNL-------- 687
            :............:|...|:   :.:|   |::.| ::.|::.   :.:|...||.|
  Fly   527 LNYDATGQLANGQWSARAIIRFGLRAGCYLGVRYS-NATLTVN---ENIADTEGLRLALDTYRHR 587

  Fly   688 ---TPTQIFFLVSAQELCAE-------SNYLGIDTNAPEFDNILGWLVAQGGSATEVFKCPSGSM 742
               |..:.||:..||..|..       |.:.|   :|...:|::|.:...|    :.|:|.:.|.
  Fly   588 SGATNLRTFFVAFAQNWCGTVASTSGLSQHAG---HAERVNNVVGNMPEFG----DTFECKATSQ 645

  Fly   743 INVQKTCNV 751
            :|....|::
  Fly   646 MNPVNKCHI 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	137/707 (19%)
Nep6	NP_572831.2	M13	40..653	CDD:341056	136/704 (19%)