Protein Alignment Nepl16 and frma

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 682
• Identity: 126/682 - (18%)
• Similarity: 220/682 - (32%)
• Gaps: 205/682 - (30%)

  Fly   167 IQARLNWNKDPCTEFKKFSC--WRNTPNKNITNLIEMGNSQKSVDSQMLYLFQNKIMN------- 222
            :|.:.:...|||..|.|.:|  |         :.....:|.:|...::.|.:|.|:.:
  Fly    17 VQVKSHPQADPCQNFYKVACGNW---------SASHATDSYESFMDRLDYNYQEKLADLLDNERE 72

  Fly   223 ----GSFGILHNLFESCLQQTTNSTVMHRIFDSL-------GGYLPVGSVGPSSIAPLIAKIYDL 276
                .....|.|.:.:|.:..:...|: ||.:.|       ...|.||......:..||    ||
  Fly    73 DDEPHFLQQLRNFYTACRKPLSQDQVL-RILEHLIVMENIQNEELSVGLTAAFRLQVLI----DL 132

  Fly   277 GPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLLADLIENF 341
            ..|...|::..| ...|.|     ..|:|::            :.|.:  |:...||.|.|.:..
  Fly   133 NDSNTYDIWKQL-MSHRKH-----WDPNTTN------------REPLT--REMFDKLWASLPKIP 177

  Fly   342 LPYFVSYAQRVSEKDTIFEFIKDLNKLQVEHSRRGFWDSTVLYNVSSLQDLYPVLNWTLLIPQNW 406
            .|:...|.:.:||.:         .|:....|....:||..|               ...||..|
  Fly   178 FPFKEYYWRELSELE---------EKIMSYGSEDDGFDSGDL---------------VTRIPPFW 218

  Fly   407 SGPIVVRNSDY-----------LKALEYFLTKYPTRVAHNSLLLLSALQI----LPRDY---PSP 453
            ..|....|..|           :||.|:.||....|:.    |:...:..    :.||.   .|.
  Fly   219 MMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLK----LVAEGVSTESWHIDRDQCAEQSR 279

  Fly   454 EVCTRSTMWALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKAHLKR-------------APSL 505
            ::.:....|          :.:.:...||:     |.:.:.:.|.||:             ..|.
  Fly   280 QILSHPAAW----------LVEKNHPRLKE-----EPVLQDIFAELKQRFGQKLLANRNNFTRST 329

  Fly   506 KGAALVKLSALKIQSQTWEGFSNTTDLLKSLQPLNITSECWFQNILEIYKKNKLEPND------I 564
            :...|.||..::::              .|:.|.|.:::...:.|...|:...:..:|      |
  Fly   330 QHFLLGKLKRMRLR--------------LSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHI 380

  Fly   565 SLN-GGSH----DAWA------------------------YPIVSTIFYDTLSHSIVVPLSVILI 600
            .|| ..||    ..||                        |...::.||....:.::||||::..
  Fly   381 GLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEP 445

  Fly   601 PYFNAVLPPYLHYASVGVSIAKEILRSITKSFDEKAMRCVPHSVNIFS----------------- 648
            |::....|..|.|:::|..:..|    ::..||.:.|....|.|...:
  Fly   446 PFYTHGQPSILTYSALGFILGHE----LSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGC 506

  Fly   649 -----NYSRMDILIHSGGMQISYHSMLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCAESNYL 708
                 ...|.:....:.|::::|.:............|.....:|..|.||...||..|::...|
  Fly   507 LRRRFGRKRYEKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQFFCSDKELL 571

  Fly   709 GIDTNAPEFDNILGWLVAQGGSATEVFKC-PS 739
            ....:..:...: ...||......|.|.| ||
  Fly   572 QAHDHGSDRKRV-NDAVAHFEPFREAFSCGPS 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	125/673 (19%)
frma	NP_572226.2	GluZincin	25..601	CDD:472708	123/671 (18%)