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Protein Alignment Nepl16 and nep-20

DIOPT Version :10

Sequence 1:	NP_001097912.1	Gene:	Nepl16 / 43014	FlyBaseID:	FBgn0039277	Length:	752	Species:	Drosophila melanogaster
Sequence 2:	NP_001317749.1	Gene:	nep-20 / 188176	WormBaseID:	WBGene00020293	Length:	834	Species:	Caenorhabditis elegans

Alignment Length:	842	Identity:	158/842 - (18%)
Similarity:	297/842 - (35%)	Gaps:	267/842 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 NLITTANPSGGSSASLLQKQLSFKTPVGSKQMGKSDEIEMID-SANIENFNTRYNKNSIIGWICC 90
            |.:..|||...:..::.:|.   |.....|:..|:::....: :|||        |:.||.  |.
Worm   138 NPVNPANPVIPAKQNMEKKN---KRKEKEKERKKAEKFSADEKTANI--------KDRIIN--CV 189

  Fly    91 APCI-----WLRTSAAVHKMAITSATLLVTTLLVASPILFLISTAPSPLPRDCYMDGDRCSPAVS 150
            .|.|     ||                          :||:               |.|..   .
Worm   190 YPVILIILFWL--------------------------LLFI---------------GARQD---E 210

  Fly   151 APPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC-----------WRNTPNKNITNLIEMGNS 204
            .|..|..|.|..:|..:.|..:.:...|..|.|.:|           .|:...|.:.
Worm   211 KPSLCESPQCITLAFELSAYQDTSVSKCHNFYKATCGKYKHHQALDKHRDAKKKEVV-------- 267

  Fly   205 QKSVDSQMLYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPL 269
             |.:..:.|...::.|.:.....:..:|..|.:.:.|.|           ||.:
Worm   268 -KRIVREFLRRNESSITSKFEPAIRLMFGKCNKFSQNKT-----------YLDI----------- 309

  Fly   270 IAKIYDLGPSPLVDL-YHDLSYGRRPHILLIISGPSTSSTILERKIRWMS----PKAPPSRIRQG 329
            ...|..:||.|::.. :.|:.:....::|.::....|...:.:.:.|.::    |...||..:||
Worm   310 FKDIEKIGPWPVLKSDWVDVMFNLNDYLLSLVELGFTDFGLFKLEFRQLAFGQFPVIAPSEQKQG 374

  Fly   330 --VPKLLADLIENFLPYFVSYAQRV-SEKDTIFEFIKDLN--KLQVEH-SRRGFWDSTVLYNVSS 388
              :.|::.:::|         |..| :::..:.:::::.:  |.|:.| |..|.....:.||.|:
Worm   375 NQLEKIILEILE---------ANGVQADRQKLSKYLREYSEFKSQLRHMSLEGTSVKYIRYNAST 430

  Fly   389 L--------QDLYPVLNWTLLIPQNWSGPIVVRNSD-------------------------YLKA 420
            |        |.:.|:...:.|:.:..||.::..:|.                         ::.|
Worm   431 LSVNISALVQKMAPMSTSSGLVRRIQSGILITNSSSFFGKNLDAIIQQTHKRTLANYLIFHFIDA 495

  Fly   421 LEYFLTKYPTRVAHNSLLLL--SALQILPRDYPSPEVCTRSTMWALPELSSSL------YIAQHS 477
            :.:.||.......|..:.||  .:||:|.:|:...|     ....:.|::..|      .|::.|
Worm   496 VTFDLTSGAKHSEHTLIDLLPRGSLQVLSQDFVDEE-----DQGVMVEMAKDLKKHVVEMISEGS 555

  Fly   478 SEDLKDTTKRAEIIFKSLKAHLKRAPSLKGAALVKLSALKIQSQTWEGFSNT--TDLLKSLQPL- 539
            |.|      :..::|:. |...|....::...:|....|:|.:|.:|..:.|  ..|.|.:|.|
Worm   556 SLD------KGHLVFEE-KERRKLIRKVQDILVVTKYPLEILNQNFEKLNLTYSDSLHKIIQKLR 613

  Fly   540 NITSECWFQNILEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLSVILIPYFN 604
            ...||    .::| |....|:|.|..:.|.:|            |:..::.:::...:|..|||:
Worm   614 RFRSE----QLIE-YLGGDLDPTDKGMWGSAH------------YEQATNDLIIIAPIIDGPYFD 661

  Fly   605 AVLPPYLHYASVGVSIAKEILRSITK---SFDEKAMRCVPHSVNIFSNYS--RMD---------- 654
            ...|.|::...:|..|::|:.||:..   ..|||.     |:.|...:.|  |.|
Worm   662 TSYPNYVNIFFMGFIISRELGRSLDSVRIRKDEKG-----HTENWLKSESLKRFDNNVKCWRKKI 721

  Fly   655 --------ILIHSGGMQISYHSMLSLTGPIKG--MARLPGL-NLTPTQIFFLVSAQELC------ 702
                    :|....|.:.|:.::......:.|  :.::.|. ::|..||||.:.|...|
Worm   722 TGTRFLNEMLADHVGHEASFMALKKWEKEMNGTIVEKIRGYESMTMEQIFFHLQALYFCRPPGGS 786

  Fly   703 --------AESNYLGIDT-------NAPEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTC 749
                    |..:|   .|       |.|:|              .:.|.|.|...:|.:..|
Worm   787 TGELTAKDARQHY---STRVNEAFKNMPQF--------------AKAFGCSSNQNMNSKTKC 831

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.