Protein Alignment Nepl16 and nep-23

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_503004.2
• Gene: nep-23 / 178472
• WormBaseID: WBGene00013785
• Length: 714
• Species: Caenorhabditis elegans
• Alignment Length: 751
• Identity: 145/751 - (19%)
• Similarity: 243/751 - (32%)
• Gaps: 267/751 - (35%)

  Fly   155 CSDPICEAVASSIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGNSQKSVDSQMLYLFQNK 219
            |..|.|..:|..:....:.:.|||..|.:..|     .|...:.::.|.::|.:
 Worm    76 CQTPECITLAHQLHNYHDPSADPCDNFYQSVC-----GKQHEHSLKSGLAKKHL----------- 124

  Fly   220 IMNGSFGILHNLFESCLQQTTNSTV---------MHRIFDSLGGYLPVGSVGPSSIAPLIAKIYD 275
                   ||.||....:   ||..|         |.:.......|....|   ||         |
 Worm   125 -------ILRNLIRETI---TNRKVTPTSKSENEMRKFHGICSKYQRANS---SS---------D 167

  Fly   276 LGPSPLVDLYHDL-SYGRRPHILLIISGPSTSSTILERKIRWMSPKAPPSRIRQGVPKLLADLIE 339
            :....|.|::.|: |.|         |.|:.|....|...              .:.::|.:|::
 Worm   168 IAQQALRDIFRDVQSIG---------SWPAGSRNWNESDF--------------NLNEMLNNLVK 209

  Fly   340 ----NFLPYFVSYAQR----VSEKD-------------TIFE----------FIKDLN---KLQV 370
                ||..:.:|:..|    :|.::             .|||          .:|||.   .|:.
 Worm   210 LGQRNFGLFQISFKYRDQLLISAEEHRRNYSKLEPTILNIFETNGLVPDRIQLLKDLEGFASLEA 274

  Fly   371 EHSRRGFWDSTVLYNVSSLQDLYP----------------------------VLNWTLLIPQNWS 407
            ......:.|:......:.|.||.|                            |||.||...:|.:
 Worm   275 LLKNHYYLDNMDKMKPAVLDDLVPSVDFMGLVKAMISPGKEHLMPKIELKTSVLNQTLFNDENMN 339

  Fly   408 GPIVVRNSDYLKALEYFLTKYPTRVAHNSLL---LLSALQILPRDYPSPE--VCTRSTMWALPEL 467
                         ||..:...|.|...|.|:   :.|:|..|..:..|.:  .|....:..||..
 Worm   340 -------------LEAIILDTPKRTLANYLIFNFIDSSLDHLVFETTSQKGNTCEDKVITYLPRA 391

  Fly   468 SSSLYIAQHSSEDLKD-TTKRAEIIFKSLKAHLKRAPSLKG----AALVKLSALKIQSQTWEGFS 527
            |..::|..:..::.:| .|:.||....:|...::.:..||.    .||.|::|:.......:.|.
 Worm   392 SLRVFIRNYVDKENRDLITQLAEKTRIALHTLVQNSTWLKAESKQLALDKINAMGKMIGYPDFFE 456

  Fly   528 NTTDLLKSLQPLNITSECWFQNILEIYKKNKLE---------------PNDISLNGGSHDAWAYP 577
            ....|....:.||:.|...:...|     ||||               |.|..|.....:|:.|.
 Worm   457 PPGTLDGMFKNLNLDSSDTYYTAL-----NKLERYFVEQKMDYFAEETPLDPDLRVFEMNAYYYI 516

  Fly   578 IVSTI-----FYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKE---------ILRSI 628
            ..:.:     |:|.              |.|::..|.|::.|..|..|..|         |||::
 Worm   517 PGNQLNFLAPFFDD--------------PMFDSTYPDYVNIAMSGNIIGHEMGHAFGPHAILRTV 567

  Fly   629 -----------TKSFDEKAMRCVPHSVNIFSNYSRMD-------------ILIHSGGMQISYHSM 669
                       ...::.:| :|:   .|.:|.|...|             ::..:.|.::|:...
 Worm   568 RGREVWMKPEELAEYESRA-QCL---ANQYSEYDDPDFGRVFDGGKVIDELVADNIGREVSWKMF 628

  Fly   670 LSLTGPIKGMARLPGL-NLTPTQIFFLVSAQELCA-----------ESNY-------LGIDTNAP 715
            .||  .:....|:.|. :....|::|.|.|...|.           ||::       .|:..|.|
 Worm   629 KSL--DLTNATRIIGFEDYDIDQLYFRVGALTHCTPHAMRDLKGSIESSHPRKAFRVNGVYANLP 691

  Fly   716 EFDNILGWLVAQGGSATEVFKCPSGSMINVQKTCNV 751
            ||              ...|.||:||.:|.:|.|::
 Worm   692 EF--------------ARAFNCPTGSPMNPRKKCDM 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	140/727 (19%)
nep-23	NP_503004.2	M13	96..711	CDD:341056	140/727 (19%)