Protein Alignment Nepl16 and nep-10

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 794
• Identity: 151/794 - (19%)
• Similarity: 275/794 - (34%)
• Gaps: 249/794 - (31%)

  Fly   106 AITSATLLVTTLLVASPILFLISTAP-----SPLPRDCYMDGDRCSPA--------VSAPPE-CS 156
            |:....|:|...||...|...|..||     .||||.   |.|: .||        |..|.. |.
 Worm    18 ALNLLLLIVFLALVTVHIKMTIDVAPVFKSDDPLPRG---DPDQ-KPATIDSETQTVDEPRNVCE 78

  Fly   157 DPICEAVASSIQARLNWNKDPCTEFKKFSCWRNTPNKNITNLIEMGN--SQKSVDSQML--YLFQ 217
            .|.|..:|..:....:.:.|||.:|.:..|.:...:    :.|..|.  :::|..|:::  :|.:
 Worm    79 SPECITLAHELHNYKDPSVDPCQDFYQHFCGKFYEH----SAIGQGRMATKRSTLSKLIREFLLK 139

  Fly   218 NKIMNG-SFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIAKIYDLGPSPL 281
            ||.... |...:..::..|.:       :.:|.|       :.|:.|.::..:.:.|..:|..|:
 Worm   140 NKTSTSKSENTMKQVYAKCRE-------LQKISD-------LNSIPPQALLDIFSDIKKIGAWPV 190

  Fly   282 VD--------------------------LYHDLSYGRRPHILLIISGPSTSSTILERKIRWMSPK 320
            :|                          .:| ..:..||::|:
 Worm   191 LDKDWDGSKFNLNEMLRQLVNLGETHLGFFH-FDFIARPYVLI---------------------- 232

  Fly   321 APPSRIRQGVPKLLADLIENFL--PYFVSYAQRVSEK-DTIFEFIKDLNKLQVEHSRRGFWDSTV 382
            .||  ::|||.|.:.:.:...:  ...:...|..||. |..||.   .|:::::...|     |.
 Worm   233 KPP--LKQGVQKSVLEKVVKMILEANEIKMDQGFSEDLDEYFEL---SNRIKIDKLPR-----TS 287

  Fly   383 LYNVSSLQDLYPVLNWTLLI----PQN---------------WSGPIVVRNSDYLKALEYFLTKY 428
            ...|..|.|:..: |:..||    |::               :..|:.||::: ...|:..:...
 Worm   288 RSIVGLLPDVRRI-NFRGLILEMMPRSKMNRFLGTLFQKVVTYHHPLFVRDNE-TNHLDTIIRST 350

  Fly   429 PTRVAHNSLL---LLSALQILPRDYPSP-EVCTRSTMWALPELSSSLYIAQ-----HSSEDLKDT 484
            ..|...|.|:   :.|:::.|.....|. |.|.:..:..||..|..:::..     :..|..|.|
 Worm   351 SNRALANYLIFNFIHSSIKFLTFGLKSDRERCEKIVVQELPRPSLRVFMRNCVDKGNREEVAKLT 415

  Fly   485 TKRAEIIFKSLKAHLKRAPSLKGAALVKLSAL------------------KIQSQTWEGFSNTTD 531
            ....|.:.:.::......||:|...|.|:.|:                  :.::.|.:...:...
 Worm   416 ETVKENVLEMIRESDSFTPSVKKRVLKKVEAIGAIIGYPDHFDPPGTLDKEYENLTLDASDSYYK 480

  Fly   532 LLKSLQPLNITSECWFQNILEIYKKNKLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHSIVVPLS 596
            :.:.|..|.:..:..|     :..:..|.|:|..|...:|            ||:..:::.|...
 Worm   481 MSQKLHQLRLQHQMEF-----LAGQTPLSPSDQVLEVNAH------------YDSKDNALTVLAP 528

  Fly   597 VILIPYFNAVLPPYLHYASVGVSIAKEILRSI------------TKSFDE--KAMRCVPHSVNIF 647
            .:..|:|::..|.|::....|..|..|...||            |:...|  |..:|:   ::.:
 Worm   529 FLDDPFFDSTYPEYVNLIFTGFLIGHEFGHSIDPKILRRDGWYKTEDMTEYGKRAQCL---IDQY 590

  Fly   648 SNYSRMDILIHSGGMQISYHSMLSLTGPIKG-------------------MARLPGL---NLTPT 690
            .||...|   |...|..:|     ..|.|.|                   |.:|.|.   ||  .
 Worm   591 DNYDDPD---HGKQMNGTY-----CIGEIVGDWVGRDVTWRAFKKMDLSKMQKLIGFEDKNL--D 645

  Fly   691 QIFFLVSAQELCAESNYL------------------GIDTNAPEFDNILGWLVAQGGSATEVFKC 737
            |::|.:.:...|...:..                  ||.:|.|:|              .:.|.|
 Worm   646 QLYFRIQSLFFCGPRSMKSLEQLLSDPHPTEVFRVNGIYSNMPQF--------------AKAFNC 696

  Fly   738 PSGSMINVQKTCNV 751
            |.||.:|.:|.|.:
 Worm   697 PIGSPMNPEKKCKM 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	127/707 (18%)
nep-10	NP_494532.2	M13	97..709	CDD:341056	127/708 (18%)