Protein Alignment: Nepl16 and Ece2

• Sequence 1: NP_001097912.1
• Gene: Nepl16
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_006521754.2
• Gene: Ece2
• MGIID: 1101356
• Length: 787
• Species: Mus musculus
• Alignment Length: 718
• Identity: 149/719 (21%)
• Similarity: 252/719 (35%)
• Gaps: 186/719 (26%)

  Fly   108 TSATLLVTTLLVASPILFLISTAPSPLPRDCYMDGDRCSPAVSAPPECSDPICEAVASSIQARLN 172
            |...|::..|::....|.|.......:.||         ||.|.   |....|..||..|...|:
Mouse    57 TQLELVLAGLILVLAALLLGCLVALWVHRD---------PAHST---CVTEACIRVAGKILESLD 109

  Fly   173 WNKDPCTEFKKFSC--W-RNTPNKNITNLIEMGNSQKSVDSQML-YLFQNKIMNGSFGI---LHN 230
            ....||.:|.:|||  | |..|..|..:.....||....:..:| :|.:|...|.|...   ..:
Mouse   110 RGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRS 174

  Fly   231 LFESCLQ----QTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIAKIYDLGPSPLVDLYHDLSYG 291
            .:.||||    :...:..:..:.|.:||:...|.....|...::..:..             :|.
Mouse   175 FYLSCLQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAG-------------TYR 226

  Fly   292 RRPHILLIISGPSTS--STILERKIRWMSPKAPPSR----IRQGVPKLLADLIENFLPYFVSYAQ 350
            ..|...:.:|..|.|  |.|::..   .|....|||    .|....|:|.    .:|.|.|....
Mouse   227 ATPFFTVYVSADSKSSNSNIIQVD---QSGLFLPSRDYYLNRTANEKVLT----AYLDYMVELGV 284

  Fly   351 RVSEKDT--------IFEFIKDLNKLQVEHSRRGFWDSTVLY---NVSSLQDLYPVLNWT----- 399
            .:..:.|        :.|....|..:.|...:|.  |...:|   ::|.||.|.|.::|.
Mouse   285 LLGGQPTSTREQMQQVLELEIQLANITVPQDQRR--DEEKIYHKMSISELQALAPAVDWLEFLSF 347

  Fly   400 LLIPQNW--SGPIVVRNSDYLKALEYFLTKYPTRVAHNSLL------LLSAL---------QILP 447
            ||.|...  |.|:||..::||:.:...:.:....:.:|.|:      ..|:|         ::|.
Mouse   348 LLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLE 412

  Fly   448 RDY-------PSPEVCTRSTMWALPELSSSLYI-------AQHSSEDLKDTTKRA------EIIF 492
            ..|       |..:.|..:|..||.....||::       ::..:|.:.:..:.|      ::::
Mouse   413 TLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVW 477

  Fly   493 KSLKAHLKRAPSLKGAALVKLSAL-------------KIQSQTWEGFSNTTDLLKSLQPLNITSE 544
            ...|..|        ||..|..|:             |.....::|:             .::.:
Mouse   478 MDEKTRL--------AAKEKADAIYDMIGFPDFILEPKELDDVYDGY-------------EVSED 521

  Fly   545 CWFQNILEIYKKNKLEPNDISLNGGSHDAWAY-PIVSTIFYDTLSHSIVVPLSVILIPYFNAVLP 608
            .:|||:|.:|..:.....|......|.|.|:. |.....:|....:.||.|..::..|::....|
Mouse   522 SFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHP 586

  Fly   609 PYLHYASVGVSIAKEILRSITKSFD------EKAMRCVP----HSVNIFSNYSRMDILIHSGGMQ 663
            ..|::..:||.:..|    :|.:||      :|.....|    .|:..|.|        |:..|:
Mouse   587 KALNFGGIGVVMGHE----LTHAFDDQGREYDKEGNLRPWWQNESLTAFQN--------HTACME 639

  Fly   664 ISYHSMLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCAESNYLGIDTNAPEFDNILGWL---V 725
            ..| |...:.|     .||.||......|     |.....::.|           |:.||:   |
Mouse   640 EQY-SQYQVNG-----ERLNGLQTLGENI-----ADNGGLKAAY-----------NVSGWVPQTV 682

  Fly   726 AQG 728
            ::|
Mouse   683 SKG 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	133/651 (20%)
Ece2	XP_006521754.2	M13	112..673	CDD:189000	128/638 (20%)
		PKc_like	<670..>706	CDD:304357	6/28 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000