Protein Alignment Nepl16 and mme

DIOPT Version :10

• Sequence 1: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 753
• Identity: 154/753 - (20%)
• Similarity: 265/753 - (35%)
• Gaps: 213/753 - (28%)

  Fly   155 CSDPICEAVASSIQARLNWNKDPCTEFKKFSC--W---RNTPNKNITNLIEMGNSQKSVDSQMLY 214
            |:...|.:.|:.|.|.::...|||.:|.:::|  |   ...|:.||     :.|:...:.:.:..
 Frog    50 CTSQACISTAARIIANMDAATDPCNDFYQYACGGWLKKNRIPDNNI-----VSNTFDILRTDIEV 109

  Fly   215 LFQNKIMNGS------FGILHNLFESCLQQTTNS--------TVMHRIFDSLGGYLPV------- 258
            :.::.:...|      ...:...::||:.:|..:        ..:..::|     .|:
 Frog   110 VLKDALEKESADDIPAIKKVKTFYKSCIDETIKNLRKGGPLIKTLPALYD-----WPIAVDNWET 169

  Fly   259 --GSV--GPSSIAPLIAKIYDLGPSPLVDLYHDLSYGRRPHILLIISGPSTSSTILERK----IR 315
              |.|  ...|||..|.|   .|.|.|:::|...........:|.|..|...   |..|    .:
 Frog   170 RYGLVWSAQESIAGFITK---YGQSGLINVYVSEDLTNSSTYILHIDQPGLG---LPSKDYYDCK 228

  Fly   316 WMSPKAPPSRIRQGVPKLLADLIENFLPYFVSYAQRVSEKDTIFEFIKDLNKLQV-EHSRRGFWD 379
            ..|..|..:.:.|.|.  :|.||.......::..:.:||.:.:|:..:::.|.:. |..|....|
 Frog   229 GTSEIACLAYMEQMVS--VAMLIRKERNLTINEDKILSEMEKVFKLEREIAKAEASEEIRENLND 291

  Fly   380 STVLYNVSSLQDLYPV------LNWTLLIPQNWS--GPIVVRN-------SDYLKALEYFLTKYP 429
            ......:|.:...||:      :||..||....|  |..:..|       |||||.|. ||.||.
 Frog   292 IYKKMTLSGIAKTYPLKMNDQNINWLKLINAIISPGGVSIEENEQVALICSDYLKKLR-FLNKYK 355

  Fly   430 TRVAHNSL---LLLSALQILPRDYPSPEVCTRSTMWA------------------LPELSSSLYI 473
            .|...|.|   .:|||:..|..:|.:..:..:..::.                  :.:....||:
 Frog   356 ARELQNYLGWRYILSAINDLSLEYKNTGIHLKKALYGNAAEGSDWQTCVTYLNDNMEDAIGRLYL 420

  Fly   474 AQHSSEDL-----KDTTKRAEIIFKSLKAHLKRAPSL-------KGAALVKLSALKIQSQTWEGF 526
            .:..|.|:     ||..|  |||.:..:|.|:....:       |..|..|::::..:....|..
 Frog   421 KETLSADIEHVKVKDKVK--EIIAEIRRAFLEMLEEMDWMDEDTKKRAARKVASINERIAFSEDI 483

  Fly   527 SNTTDLLKSLQPLNITSECWFQN---------------ILEIYKKNKLEPNDISLNGGSHDAWAY 576
            .:...|.:....|....:..|:|               :.:...||:..|....:|.
 Frog   484 MDDFKLNEGYSELEFRVDELFENKQKYIEFVQKKMTSRLRKQVNKNEWVPGPAHVNA-------- 540

  Fly   577 PIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKSFDEKAMRCVP 641
                  ||....:.||.|..::..|:|::..|..|:|..:|:.|..|    ||..||.:......
 Frog   541 ------FYSLTYNEIVFPAGILQTPFFSSSQPSALNYGGIGMIIGHE----ITHGFDNRGCNFDE 595

  Fly   642 HS---------------------VNIFSNYSRMDILIHSGGMQISYHSML----SLTGPIKGMAR 681
            |.                     ||.:.|||..:    :||..::..|.|    |..|.|:|..|
 Frog   596 HGNLVNWWTNASMMNFSNLSQCFVNQYGNYSWDE----AGGQYLNGISTLGENISDNGGIRGAYR 656

  Fly   682 --------------LPGLNLTPTQIFFLVSAQELCA--ESNY-----------------LGIDTN 713
                          |||::|...|:||:...|..|.  ...|                 :|...|
 Frog   657 AFKNYVKSHKEDDLLPGIDLDSDQLFFISFGQIWCGMHRPEYAATLIKTGSHTPGIFRVIGTLQN 721

  Fly   714 APEFDNILGWLVAQGGSATEVFKCPSGSMINVQKTCNV 751
            :|||              ::.|.|.:.:.:|....|.:
 Frog   722 SPEF--------------SKAFSCCNNAYMNPAVKCKL 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	148/729 (20%)
mme	XP_031758820.1	M13	71..744	CDD:341056	148/729 (20%)