Protein Alignment Stt3B and Stt3b

DIOPT Version :10

• Sequence 1: NP_524494.1
• Gene: Stt3B / 43005
• FlyBaseID: FBgn0011336
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: NP_077184.2
• Gene: Stt3b / 68292
• MGIID: 1915542
• Length: 823
• Species: Mus musculus
• Alignment Length: 771
• Identity: 552/771 - (71%)
• Similarity: 642/771 - (83%)
• Gaps: 16/771 - (2%)

  Fly    10 SKVAGYSSLITFAILLIAWLAGFSSRLFAVIRFESIIHEFDPWFNYRATAYMVQNGWYNFLNWFD 74
            |:.||:.||::|.||.:||||||||||||||||||||||||||||||:|.::..:|:|.||||||
Mouse    60 SQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHLASHGFYEFLNWFD 124

  Fly    75 ERAWYPLGRIVGGTVYPGLMITSGGIHWLLHVLNIPVHIRDICVFLAPIFSGLTSISTYLLTKEL 139
            ||||||||||||||||||||||:|.|||:|:.|||.|||||:||||||.|||||||||:|||:||
Mouse   125 ERAWYPLGRIVGGTVYPGLMITAGLIHWILNTLNITVHIRDVCVFLAPTFSGLTSISTFLLTREL 189

  Fly   140 WSAGAGLFAASFIAIVPGYISRSVAGSYDNEGIAIFALQFTYFLWVRSVKTGSVFWSAAAALSYF 204
            |:.||||.||.||||||||||||||||:||||||||||||||:|||:|||||||||:....||||
Mouse   190 WNQGAGLLAACFIAIVPGYISRSVAGSFDNEGIAIFALQFTYYLWVKSVKTGSVFWTMCCCLSYF 254

  Fly   205 YMVSAWGGYVFIINLIPLHVFVLLIMGRYSPRLLTSYSTFYILGLLFSMQIPFVGFQPIRTSEHM 269
            ||||||||||||||||||||||||:|.|||.|:..:||||||:||:.||||||||||||||||||
Mouse   255 YMVSAWGGYVFIINLIPLHVFVLLLMQRYSKRVYIAYSTFYIVGLILSMQIPFVGFQPIRTSEHM 319

  Fly   270 AALGVFVLLMAVATLRHLQSVLSRNEFRKLFIVGGLLVGVGVFVAVVVLTMLGVVAPWSGRFYSL 334
            ||.|||.||.|.|.|::|:..|::.||:.||.:|..|....||::|:.||..|.:||||||||||
Mouse   320 AAAGVFALLQAYAFLQYLRDRLTKQEFQTLFFLGVSLAAGAVFLSVIYLTYTGYIAPWSGRFYSL 384

  Fly   335 WDTGYAKIHIPIIASVSEHQPTTWFSFFFDLHILVCAFPVGVWYCIKQINDERVFVVLYAISAVY 399
            ||||||||||||||||||||||||.|||||||||||.||.|:|:|||.||||||||.||||||||
Mouse   385 WDTGYAKIHIPIIASVSEHQPTTWVSFFFDLHILVCTFPAGLWFCIKNINDERVFVALYAISAVY 449

  Fly   400 FAGVMVRLMLTLTPVVCMLAGVAFSGLLDVFLQEDSSKRMGTAISAATEVDEAEDSIEKK---TL 461
            |||||||||||||||||||:.:|||.:.:.:|.:|..:.       ...|:::.|..:|:   .|
Mouse   450 FAGVMVRLMLTLTPVVCMLSAIAFSNVFEHYLGDDMKRE-------NPPVEDSSDEDDKRNPGNL 507

  Fly   462 YDKAGKLKHRTKHDAQQDTGVSSNLKSIVILAVLMLLMMFAVHCTWVTSNAYSSPSIVLAFHNSQ 526
            ||||||::.......:.:.|:..|:||||.:.:|||||||||||||||||||||||:|||.:| .
Mouse   508 YDKAGKVRKHVTEQEKPEEGLGPNIKSIVTMLMLMLLMMFAVHCTWVTSNAYSSPSVVLASYN-H 571

  Fly   527 DGSRNILDDFREAYYWLSQNTADDARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMS 591
            ||:|||||||||||:||.|||.:.|||||||||||||||||||||||||||||||||||||||||
Mouse   572 DGTRNILDDFREAYFWLRQNTDEHARVMSWWDYGYQIAGMANRTTLVDNNTWNNSHIALVGKAMS 636

  Fly   592 STEEKSYEIMTSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIKESDYFTDRGEFRV 656
            |.|..:|:||.||||||||||||||||||||||||||||||||||||||||:|.||||.:|||||
Mouse   637 SNETAAYKIMRSLDVDYVLVIFGGVIGYSGDDINKFLWMVRIAEGEHPKDIREGDYFTQQGEFRV 701

  Fly   657 DAEGAPALLNCLMYKLSYYRFGELKLDYRGPSGYDRTRNAVIGNKDFDLTYLEEAYTTEHWLVRI 721
            |..|:|.||||||||:|||||||::||:|.|.|:||||||.|||||....:||||:|:|||||||
Mouse   702 DKAGSPTLLNCLMYKMSYYRFGEMQLDFRTPPGFDRTRNAEIGNKDIKFKHLEEAFTSEHWLVRI 766

  Fly   722 YRVKKPHEFNRPSLKTKERT---IPPANFISRKNSKRRKGYIRNRPVVVKGKRTLK 774
            |:||.|.  ||.:|..|.|.   :|...::|:|.:||::||::|:.|..|||:|.|
Mouse   767 YKVKAPD--NRETLGHKPRVTNIVPKQKYLSKKTTKRKRGYVKNKLVFKKGKKTSK 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Stt3B	NP_524494.1	STT3	18..514	CDD:396873	356/498 (71%)
Stt3b	NP_077184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58
		STT3	68..560	CDD:396873	356/498 (71%)
		DXD motif 1. /evidence=ECO:0000250|UniProtKB:Q5HTX9	98..100		1/1 (100%)
		DXD motif 2. /evidence=ECO:0000250|UniProtKB:P39007	218..220		1/1 (100%)
		SVSE motif. /evidence=ECO:0000250|UniProtKB:Q5HTX9	399..402		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	487..526		10/45 (22%)
		WWDYG motif. /evidence=ECO:0000250|UniProtKB:P39007	601..605		3/3 (100%)
		Interacts with target acceptor peptide in protein substrate. /evidence=ECO:0000250|UniProtKB:B9KDD4	601..603		1/1 (100%)
		DK motif. /evidence=ECO:0000250|UniProtKB:P39007	668..675		6/6 (100%)