Protein Alignment CG31109 and KMT2D

DIOPT Version :8

• Sequence 1: NP_001262946.1
• Gene: CG31109 / 43001
• FlyBaseID: FBgn0051109
• Length: 198
• Species: Drosophila melanogaster
• Sequence 2: XP_011537072.1
• Gene: KMT2D / 8085
• HGNCID: 7133
• Length: 5556
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 30/164 (18%)
• Similarity: 60/164 (37%)
• Gaps: 35/164 (21%)

  Fly    26 HIYSDHGQRLCLVEKINGYLPITISPTDPLPK--TICKSCLHRVEQ--------HYSLLMRLTRM 80
            |:.:..||     |:..|      .|:.|.|.  |..:..::..:|        |...|:::...
Human  3476 HVAAGSGQ-----ERSAG------DPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLK 3529

  Fly    81 ---------REERKFKLIKYKAQRNPSISSVESEEDVINSSSVHEFPNRNEEDQATR-RSESTST 135
                     |:.||....|.:..:.......|::.:.:...:..:...:.:.||..: :.|.|:.
Human  3530 VLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNL 3594

  Fly   136 QAE----TGPQTQESQSPKSTKTAVSTPNSSES 164
            .||    ...|.|:.|..:...:||...:.|:|
Human  3595 MAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQS 3627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31109	NP_001262946.1	zf-AD	13..76	CDD:214871	12/60 (20%)
KMT2D	XP_011537072.1	ePHD1_KMT2D	134..217	CDD:277165
		PHD1_KMT2C_like	228..273	CDD:276984
		PHD_SF	275..320	CDD:304600
		PHD3_KMT2D	1378..1428	CDD:277072
		PHD5_KMT2C_like	1429..1475	CDD:276988
		PHD5_KMT2D	1506..1556	CDD:277074
		HMG	2024..2075	CDD:197700
		ePHD2_KMT2D	5035..5141	CDD:277168
		FYRN	5185..5235	CDD:283589
		FYRC	5243..5330	CDD:197781
		SET	5416..5538	CDD:214614

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG4443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900