Protein Alignment mah and SLC38A5

DIOPT Version :10

• Sequence 1: NP_651316.1
• Gene: mah / 42988
• FlyBaseID: FBgn0285912
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: XP_054184094.1
• Gene: SLC38A5 / 92745
• HGNCID: 18070
• Length: 541
• Species: Homo sapiens
• Alignment Length: 544
• Identity: 115/544 - (21%)
• Similarity: 203/544 - (37%)
• Gaps: 169/544 - (31%)

  Fly    22 ALPKRR-----------PPVQLTPSHQHD-----QLPF----LRRSRFSALP-----------HF 55
            |:|.|:           ||.|.|.....|     .||.    .|:.|...||           .|
Human    24 AVPTRQGLQARVGIAETPPPQETRMELQDPKMNGALPSDAVGYRQEREGFLPSRGPAPGSKPVQF 88

  Fly    56 RAYEDEPE-NLSLF-----------IAILYVVDLFGIFPFVTLPALLVKLGYFGILLVLSIIILQ 108
            ..:|.:.. .:|:|           :.:.|.:...|:.              |.:.|:|.|.:|.
Human    89 MDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVI--------------FFLALLLCIALLS 139

  Fly   109 IYTSFLLSQCWTMAELLDPSIQQKRNYPYAALAELAYGPYMSLLVSVLLDL-SIFAMA------- 165
            .|:..||..|..:|.:          ..|..|.:.|:||...::|:.::.| ::.||:
Human   140 SYSIHLLLTCAGIAGI----------RAYEQLGQRAFGPAGKVVVATVICLHNVGAMSSYLFIIK 194

  Fly   166 --VPSVVMAAQNLEGVVLRMS-AGQYNFSYCYWAIIVG-LVICPLMWLGSPKHM------RGLAI 220
              :|.|:       |..|.|. .|.:........|||. |:|.||..:   ||:      .||::
Human   195 SELPLVI-------GTFLYMDPEGDWFLKGNLLIIIVSVLIILPLALM---KHLGYLGYTSGLSL 249

  Fly   221 IAVCVMIVIVALLW--FCLFAA-----------PAIGTPFEGISLELPGFLTVLN---SYS--IL 267
              .|::..:|::::  |.|..|           ..:|.|.:|::......:..::   ||:  |:
Human   250 --TCMLFFLVSVIYKKFQLGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVDSQMSYTVPIM 312

  Fly   268 AFQFDIHPVLLTLQIDMKQKSQVSWAALIGIAITCSVAIFGSIIAAY---KFGSMIADNLLQSLP 329
            ||.|..||.:|.:..::.:.|:....|:..::|.....::| :.|.:   .|.|.:...:|....
Human   313 AFAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYG-LTATFGYLTFYSSVKAEMLHMYS 376

  Fly   330 TSVPFYVMLILMALQLCFSVTVASSAMFMQIE----------NYFKLPESLSFKRMLIRSSVLAL 384
            ...|   :::.:.|.:..:||:....:...|.          ..|..|..::...:|:    :.:
Human   377 QKDP---LILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIALILL----VLV 434

  Fly   385 EVLVAEFVPSFDALMDVVGGTITGPLVFILPPLLYRRIRRMERVHQRIAAEASYGSLPLDLNYDP 449
            .|||. .||:...:..|:|.|....|:||||.:.|.||
Human   435 NVLVI-CVPTIRDIFGVIGSTSAPSLIFILPSIFYLRI--------------------------- 471

  Fly   450 VDLEMEPLLVISPPTTPRGC--WL 471
            |..|:||.|  |.|.. :||  |:
Human   472 VPSEVEPFL--SWPKI-QGCQAWI 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:444915	80/364 (22%)
SLC38A5	XP_054184094.1	SLC5-6-like_sbd	93..484	CDD:444915	95/464 (20%)