Protein Alignment mah and AVT4

DIOPT Version :10

• Sequence 1: NP_651316.1
• Gene: mah / 42988
• FlyBaseID: FBgn0285912
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_014298.1
• Gene: AVT4 / 855622
• SGDID: S000005045
• Length: 713
• Species: Saccharomyces cerevisiae
• Alignment Length: 607
• Identity: 120/607 - (19%)
• Similarity: 227/607 - (37%)
• Gaps: 185/607 - (30%)

  Fly     4 FRRQNAKPAPRPSRAPSFALPKRRPPVQLT-------PSHQH--------------DQLPFLRRS 47
            |||:             |.:.|:|...||.       .||:.              |::|||.|:
Yeast   191 FRRE-------------FIVNKKRQEHQLNDSASSDFTSHESDSINQSSPSSNQDIDKVPFLTRN 242

  Fly    48 RFSAL---PHF--RAYEDE--PENLSLFI-------AILYVVDLFGIFPFV-----TLPALLVKL 93
            ....|   .||  .::||:  |::.::.|       |:|...|...:.|..     |....|:.|
Yeast   243 FLEFLYVFGHFAGESFEDDFIPDSSNMMIRGEDERSALLSRPDHMKVLPSAKGTTSTKKVFLILL 307

  Fly    94 GYF---GIL----------LVLSIIILQIYTSFLLSQCWTMAELLDPSIQQKRNYPYAALAELA- 144
            ..|   |:|          |..|:.:|..   |.:...|....|    :|.|.:...::..::.
Yeast   308 KSFIGTGVLFLPNAFHNGGLFFSVSMLAF---FGIYSYWCYYIL----VQAKSSCGVSSFGDIGL 365

  Fly   145 --YGPYMSLLVSVLLDLSIFAMAVPSVVMAAQNLEGV--------VLRMSAGQYNFSYCYWAIIV 199
              |||:|.:::...|.::....:...::..|:||:..        ||.:|         |..:..
Yeast   366 KLYGPWMRIIILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHVGVLPLS---------YLMVFQ 421

  Fly   200 GLVICPLMW------LGSPKHMRGLAIIAVCVMIVIVAL--LWFCLFAAPAIGTPFEGISLELPG 256
            .::..||.:      |..|..:....|:|..|:::|...  |:|.|...||:|..: |::.:.
Yeast   422 TIIFIPLSFIRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPAMGVVY-GLNADR-- 483

  Fly   257 FLTVLNSYSILAFQFDIHPVLLTLQIDMKQKSQVSWAALIGIAITCSVAIFGSI--IAAYKFGSM 319
             .|:....:|.||:    .:.|.:.:....::...:..::.:.|..:..:|.||  :....:||.
Yeast   484 -WTLFIGTAIFAFE----GIGLIIPVQDSMRNPEKFPLVLALVILTATILFISIATLGYLAYGSN 543

  Fly   320 IADNLLQSLPTS-------VPFYVMLILMA--LQLCFSVTVASSAMFMQIENYF----------- 364
            :...:|.:||.|       ..||.:.|:::  |||..::.:..:..|.:....:
Yeast   544 VQTVILLNLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKIIENKFFPKFTKIYVKHDDLTTRVE 608

  Fly   365 ------KLPESLSFKRMLIRSSVLALEVLVAEF-VPSFDALMDVVGGTITGPLVFILPPLLYRRI 422
                  ||...:.:.:..|||.::.:.|.:|.| ..:.|..:.|:|.....|||:|.|.:|:.|
Yeast   609 LRPNSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLR- 672

  Fly   423 RRMERVHQRIAAEASYGSLPLDLNYDPVDLEMEPLLVISPPTTPRGCWLRFVRLLHRLECDVSCT 487
                            |:                    |.|.|....| ||..:|..:
Yeast   673 ----------------GN--------------------SLPETKGEFW-RFKPMLDTI------- 693

  Fly   488 MAVLIFGLLATFLSTYLNIFSL 509
              ::.||:.:...::|.:||.:
Yeast   694 --LIFFGIASMLYTSYQSIFGV 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:444915	72/363 (20%)
AVT4	NP_014298.1	Aa_trans	295..711	CDD:279788	92/486 (19%)