Protein Alignment mah and SLC38A8

DIOPT Version :10

• Sequence 1: NP_651316.1
• Gene: mah / 42988
• FlyBaseID: FBgn0285912
• Length: 527
• Species: Drosophila melanogaster
• Sequence 2: NP_001073911.1
• Gene: SLC38A8 / 146167
• HGNCID: 32434
• Length: 435
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 71/383 - (18%)
• Similarity: 157/383 - (40%)
• Gaps: 84/383 - (21%)

  Fly    81 FPFV------TLPALLVKLGYFGILLVLSIIILQIYTSFLLSQCWTMAELLDPSIQQKRNYPYAA 139
            ||:.      .:||.||:|  ..::.::|.:::..|.:.:..|.                 .|..
Human    45 FPWAFSKAGGVVPAFLVEL--VSLVFLISGLVILGYAAAVSGQA-----------------TYQG 90

  Fly   140 LAELAYGPYMSLLVSVLLDLSIFAMAVPSVVMAAQNLEGVVLRMSAGQYNFSYCYWA-------I 197
            :.....||.:..|......|::..::|..:.:....||.:...:.:|.......::|       :
Human    91 VVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPL 155

  Fly   198 IVGLVICPLMWLGSP------KHMRGLAIIAVCVMIVIVAL---LWFCLFAAPAIGTPFEGI--- 250
            :..|||.|   |.:|      |:...|..:|.|.:.:::.:   ||           | :|:
Human   156 LSVLVILP---LSAPREIAFQKYTSILGTLAACYLALVITVQYYLW-----------P-QGLVRE 205

  Fly   251 ---SLELPGFLTVLNSYSILAFQFDIHPVLLTLQIDMKQKSQVSWA--ALIGIAITCSVAIFGSI 310
               ||....:.:|.:.:..:.|.|..|...:::...|:::|...||  :::.:...|.:.....:
Human   206 SHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGV 270

  Fly   311 IAAYKFGSMIADNLLQSLP-TSVPFYVMLILMALQLCFSVTVASSAMFM---QIENYFKL----- 366
            .....||:.::.::|.|.| ..:...|..:|.|:.:   |||....:|:   .::::::.
Human   271 YGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSI---VTVYPIVLFLGRSVMQDFWRRSCLGG 332

  Fly   367 --PESLS-----FKRMLIRSSVLALEVLVAEFVPSFDALMDVVGGTITGPLVFILPPL 417
              |.:|:     :.||.:....:.:.:.:|.|:|....::.::|| |:...:||.|.|
Human   333 WGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGG-ISSFFIFIFPGL 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mah	NP_651316.1	SLC5-6-like_sbd	110..426	CDD:444915	63/348 (18%)
SLC38A8	NP_001073911.1	SLC5-6-like_sbd	23..431	CDD:444915	71/383 (19%)