Protein Alignment: Nmnat and NMA2

• Sequence 1: NP_651315.2
• Gene: Nmnat
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_011524.1
• Gene: NMA2
• SGDID: S000003242
• Length: 395
• Species: Saccharomyces cerevisiae
• Alignment Length: 263
• Identity: 100/264 (38%)
• Similarity: 146/264 (55%)
• Gaps: 27/264 (10%)

  Fly    39 TKSL-----LPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLA 98
            ||.|     ||.| .:|||.|||.|.:||||||:|.|....|....||||..||..|:|.|:|||
Yeast   149 TKKLQDPEKLPLI-IVACGSFSPITYLHLRMFEMALDDINEQTRFEVVGGYFSPVSDNYQKRGLA 212

  Fly    99 SALDRCAMVKLATQ-SSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHL 162
            .|..|..|.:||.: :|:|:.:..||..|:.:.||..||.|..:.||  |..||....|||
Yeast   213 PAYHRVRMCELACERTSSWLMVDAWESLQSSYTRTAKVLDHFNHEIN--IKRGGIMTVDGE---- 271

  Fly   163 PGWLPRGLHDSRDPVHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFD 227
                       :..|.:.||.|.||:||...|.:||::|:..|:.|:|.:::.|.||:...|:..
Yeast   272 -----------KMGVKIMLLAGGDLIESMGEPHVWADSDLHHILGNYGCLIVERTGSDVRSFLLS 325

  Fly   228 SDILTKYQSNITLITNWVPNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLFNFKS---KYI 289
            .||:.:::.||.:|...:.|::|||.:|..:.||.||:|||.:.|:.||:...|:..:|   |.:
Yeast   326 HDIMYEHRRNILIIKQLIYNDISSTKVRLFIRRGMSVQYLLPNSVIRYIQEYNLYINQSEPVKQV 390

  Fly   290 TDA 292
            .|:
Yeast   391 LDS 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	92/237 (39%)
NMA2	NP_011524.1	NMNAT_Eukarya	160..380	CDD:185681	92/238 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C18251770
eggNOG	1	0.900				E1_COG1057
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I1031
Isobase	1	0.950		0	Normalized mean entropy	S1288
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0001264
OrthoInspector	1	1.000				T634767
orthoMCL	1	0.900				OOG5_128044
Panther	1	1.100			O	PTHR12039
Phylome	1	0.910		0.833	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R815
TreeFam	1	0.960
	12	11.730