Protein Alignment Nmnat and NMA2

DIOPT Version :10

• Sequence 1: NP_651315.2
• Gene: Nmnat / 42987
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_011524.1
• Gene: NMA2 / 852893
• SGDID: S000003242
• Length: 395
• Species: Saccharomyces cerevisiae
• Alignment Length: 263
• Identity: 100/263 - (38%)
• Similarity: 146/263 - (55%)
• Gaps: 27/263 - (10%)

  Fly    39 TKSL-----LPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLA 98
            ||.|     ||.| .:|||.|||.|.:||||||:|.|....|....||||..||..|:|.|:|||
Yeast   149 TKKLQDPEKLPLI-IVACGSFSPITYLHLRMFEMALDDINEQTRFEVVGGYFSPVSDNYQKRGLA 212

  Fly    99 SALDRCAMVKLATQ-SSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHL 162
            .|..|..|.:||.: :|:|:.:..||..|:.:.||..||.|..:.||  |..||....|||
Yeast   213 PAYHRVRMCELACERTSSWLMVDAWESLQSSYTRTAKVLDHFNHEIN--IKRGGIMTVDGE---- 271

  Fly   163 PGWLPRGLHDSRDPVHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFD 227
                       :..|.:.||.|.||:||...|.:||::|:..|:.|:|.:::.|.||:...|:..
Yeast   272 -----------KMGVKIMLLAGGDLIESMGEPHVWADSDLHHILGNYGCLIVERTGSDVRSFLLS 325

  Fly   228 SDILTKYQSNITLITNWVPNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLFNFKS---KYI 289
            .||:.:::.||.:|...:.|::|||.:|..:.||.||:|||.:.|:.||:...|:..:|   |.:
Yeast   326 HDIMYEHRRNILIIKQLIYNDISSTKVRLFIRRGMSVQYLLPNSVIRYIQEYNLYINQSEPVKQV 390

  Fly   290 TDA 292
            .|:
Yeast   391 LDS 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	91/236 (39%)
NMA2	NP_011524.1	NMNAT_Eukarya	160..380	CDD:185681	91/237 (38%)