Protein Alignment Nmnat and NMA1

DIOPT Version :10

• Sequence 1: NP_651315.2
• Gene: Nmnat / 42987
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_013432.1
• Gene: NMA1 / 851039
• SGDID: S000004320
• Length: 401
• Species: Saccharomyces cerevisiae
• Alignment Length: 261
• Identity: 96/261 - (36%)
• Similarity: 143/261 - (54%)
• Gaps: 24/261 - (9%)

  Fly    23 FKRRSKSKKMSAFIEETKSLLPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISP 87
            |.....|||:   ::..|  || :..:|||.|||.|.:||||||:|.|....|....|:||..||
Yeast   149 FPSHRLSKKL---LDPNK--LP-LVIVACGSFSPITYLHLRMFEMALDAISEQTRFEVIGGYYSP 207

  Fly    88 THDSYGKKGLASALDRCAMVKLATQ-SSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGG 151
            ..|:|.|:|||.:..|..|.:||.: :|:|:.:..||..|..:.||..||.|..:.||  |..||
Yeast   208 VSDNYQKQGLAPSYHRVRMCELACERTSSWLMVDAWESLQPSYTRTAKVLDHFNHEIN--IKRGG 270

  Fly   152 GGGDDGENTHLPGWLPRGLHDSRDPVHLKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITR 216
            .....||               :..|.:.||.|.||:||...|.:||:||:..|:.|:|.:::.|
Yeast   271 VATVTGE---------------KIGVKIMLLAGGDLIESMGEPNVWADADLHHILGNYGCLIVER 320

  Fly   217 AGSNPGKFIFDSDILTKYQSNITLITNWVPNEVSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRL 281
            .||:...|:...||:.:::.||.:|...:.|::|||.:|..:.|..||:|||.:.|:.||:..||
Yeast   321 TGSDVRSFLLSHDIMYEHRRNILIIKQLIYNDISSTKVRLFIRRAMSVQYLLPNSVIRYIQEHRL 385

  Fly   282 F 282
            :
Yeast   386 Y 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	88/236 (37%)
NMA1	NP_013432.1	NMNAT_Eukarya	166..386	CDD:185681	88/236 (37%)