Protein Alignment Nmnat and Nmnat1

DIOPT Version :10

• Sequence 1: NP_651315.2
• Gene: Nmnat / 42987
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_006239491.1
• Gene: Nmnat1 / 298653
• RGDID: 1310996
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 125/299 - (41%)
• Similarity: 175/299 - (58%)
• Gaps: 47/299 - (15%)

  Fly    25 RRSKSKKM--------SAFIEETKSLLP-------RIAFIACGCFSPPTPMHLRMFEIAKDHFEM 74
            |||.|:.:        ...:::...|||       .:..:|||.|:|.|.||||:||:|||:...
  Rat     4 RRSSSEMLDDNNIGIRGLHLDQQLQLLPMDSSKKTEVVLLACGSFNPITNMHLRLFELAKDYLNA 68

  Fly    75 QGTHRVVGGIISPTHDSYGKKGLASALDRCAMVKLATQSSNWIRLSDWEVHQNQWMRTQAVLQHH 139
            .|.::|:.|||||..|:|.||||..|..|..|.:|||::|:|:.:..||..|.:|:.|..||:||
  Rat    69 TGEYKVIKGIISPVGDAYKKKGLIPAHHRIIMAELATKNSHWVEVDTWESLQKEWVETVKVLRHH 133

  Fly   140 QNYINNHINSGGGGGDDGENTH--------LPG----WLPRGLHDS----RDP-----VHLKLLC 183
            |..:..           |..:|        .||    |..:....|    ::|     ..:||||
  Rat   134 QEKLAT-----------GSRSHPQSSPVLERPGRKRKWADQKQDSSPQKPQEPKPTGVPRVKLLC 187

  Fly   184 GADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDILTKYQSNITLITNWVPNE 248
            ||||||||:||.||...||..||||.||:.:|||||:..|||::||:|.::||||.|:|.|:.|:
  Rat   188 GADLLESFSVPNLWKMEDITQIVANFGLICVTRAGSDAQKFIYESDVLWRHQSNIHLVTEWITND 252

  Fly   249 VSSTLIRRLLGRGQSVKYLLDDLVLEYIKRQRLFNFKSK 287
            :|||.|||.|.||||::||:.|||.|||:...|:|.:|:
  Rat   253 ISSTKIRRALRRGQSIRYLVPDLVQEYIEEHDLYNSESE 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	115/256 (45%)
Nmnat1	XP_006239491.1	NMNAT_Eukarya	40..286	CDD:185681	115/256 (45%)