back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nmnat and Nmnat2

DIOPT Version :9

Sequence 1:	NP_651315.2	Gene:	Nmnat / 42987	FlyBaseID:	FBgn0039254	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_780669.1	Gene:	Nmnat2 / 226518	MGIID:	2444155	Length:	307	Species:	Mus musculus

Alignment Length:	310	Identity:	102/310 - (32%)
Similarity:	152/310 - (49%)	Gaps:	74/310 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 EETKSLLPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLASAL 101
            |.||:   .:..:|||.|:|.|..|::|||.|:|:....|...|:|||:||.||||||:||.|:.
Mouse     3 ETTKT---HVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSR 64

  Fly   102 DRCAMVKLATQSSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHLPGWL 166
            .|..|.:||.|:|:|||:..||.:|:.|..|.:||:||::.:....      |....|.:.|...
Mouse    65 HRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVT------GCILSNVNTPSMT 123

  Fly   167 P---RGLHDSRDPVH-------------------------------------------------- 178
            |   :..|::..|::
Mouse   124 PVIGQPQHENTQPIYQNSNVPTKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRY 188

  Fly   179 ------LKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDILTKYQSN 237
                  :.||||:||||||.:||||.|||:|.||.:.|:||:.|..::..:.:..|.||.||::|
Mouse   189 EEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNN 253

  Fly   238 ITLI---TNWVPNEVSSTLIRRLL--GRGQSVKYLLDDLVLEYIKRQRLF 282
            |.::   .|...:.||||..|..|  |.|..|.| |...|::||.:.:|:
Mouse   254 IMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDY-LSQPVIDYILKSQLY 302

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.