Protein Alignment: Nmnat and Nmnat2

• Sequence 1: NP_651315.2
• Gene: Nmnat
• FlyBaseID: FBgn0039254
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_780669.1
• Gene: Nmnat2
• MGIID: 2444155
• Length: 307
• Species: Mus musculus
• Alignment Length: 310
• Identity: 102/311 (33%)
• Similarity: 152/311 (49%)
• Gaps: 74/311 (24%)

  Fly    37 EETKSLLPRIAFIACGCFSPPTPMHLRMFEIAKDHFEMQGTHRVVGGIISPTHDSYGKKGLASAL 101
            |.||:   .:..:|||.|:|.|..|::|||.|:|:....|...|:|||:||.||||||:||.|:.
Mouse     3 ETTKT---HVILLACGSFNPITKGHIQMFERARDYLHKTGRFIVIGGIVSPVHDSYGKQGLVSSR 64

  Fly   102 DRCAMVKLATQSSNWIRLSDWEVHQNQWMRTQAVLQHHQNYINNHINSGGGGGDDGENTHLPGWL 166
            .|..|.:||.|:|:|||:..||.:|:.|..|.:||:||::.:....      |....|.:.|...
Mouse    65 HRLIMCQLAVQNSDWIRVDPWECYQDTWQTTCSVLEHHRDLMKRVT------GCILSNVNTPSMT 123

  Fly   167 P---RGLHDSRDPVH-------------------------------------------------- 178
            |   :..|::..|::
Mouse   124 PVIGQPQHENTQPIYQNSNVPTKPTAAKILGKVGESLSRICCVRPPVERFTFVDENANLGTVMRY 188

  Fly   179 ------LKLLCGADLLESFAVPGLWAEADIEDIVANHGLVVITRAGSNPGKFIFDSDILTKYQSN 237
                  :.||||:||||||.:||||.|||:|.||.:.|:||:.|..::..:.:..|.||.||::|
Mouse   189 EEIELRILLLCGSDLLESFCIPGLWNEADMEVIVGDFGIVVVPRDAADTDRIMNHSSILRKYKNN 253

  Fly   238 ITLI---TNWVPNEVSSTLIRRLL--GRGQSVKYLLDDLVLEYIKRQRLF 282
            |.::   .|...:.||||..|..|  |.|..|.| |...|::||.:.:|:
Mouse   254 IMVVKDDINHPMSVVSSTKSRLALQHGDGHVVDY-LSQPVIDYILKSQLY 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmnat	NP_651315.2	NMNAT_Eukarya	46..282	CDD:185681	99/300 (33%)
Nmnat2	NP_780669.1	NMNAT_Eukarya	9..302	CDD:185681	99/300 (33%)
		Substrate binding. {ECO:0000250|UniProtKB:Q96T66}	55..57		2/2 (100%)
		Substrate binding. {ECO:0000250|UniProtKB:Q96T66}	92..95		1/3 (33%)
		Substrate binding. {ECO:0000250|UniProtKB:Q96T66}	212..213		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG1057
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR12039
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R815
TreeFam	1	0.960
	5	4.990