Protein Alignment DZIP1 and dzip1l

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_012826036.1
• Gene: dzip1l / 780329
• XenbaseID: XB-GENE-991168
• Length: 798
• Species: Xenopus tropicalis
• Alignment Length: 747
• Identity: 155/747 - (20%)
• Similarity: 281/747 - (37%)
• Gaps: 229/747 - (30%)

  Fly    16 FKLRQYRDGPLDWRLMGSYETERILREQNFELVDKALTHLS------------EAPLGTVLETHI 68
            |:.:..||| :|||...:.:||||.||.:...:.:::..::            :.|:..||
 Frog    51 FRFQPRRDG-IDWRRFSAIDTERITREVDINTLQESINSITFCNLEGEKCPYCQQPVDPVL---- 110

  Fly    69 LDSGIAKYFVMSQYAIQYLMCCRTY-------LDECVTDLKEAHTTAQEEIATLRKSLSESNNEV 126
                 .|...|:|..|:||:.|:.:       |:|.:.:.:..|...::|:|...:.:.:...|.
 Frog   111 -----LKVLKMAQMIIEYLLYCQEHIHSREAQLEERLGEAEAEHERTKDELAKQAEEMKKVKEES 170

  Fly   127 VQLHKRI-TQ---IEAIREVVYPCHLCTKNFISNEALNVHIGRKHRVASPPSLTSATGKEKDRDK 187
            .:..|.| ||   ::|.....:.|.||.|.|::...|..||.|:|     |.:|     |.:|.|
 Frog   171 KRRKKMIATQQMLLQAGANNYHKCQLCDKAFMNYSYLQGHIQRRH-----PEIT-----EIERQK 225

  Fly   188 ATDVHLINTIKMELEIKQLKERLNAAERNIKERSTGSKRVSPRQEQRHVGIQSNLAEPKEKDEDS 252
            ...|.     :||..|::||.:|...:..::|          .:|..|          |::.:::
 Frog   226 KKQVE-----QMEDGIEELKSKLLKTQAILEE----------EREMEH----------KKRLQEA 265

  Fly   253 GEARQSEASERKEQLTGLAERLSNFEEW--------QTQLKQSNEQF---IQDI---NKRLEGLS 303
            .|||..|.:.:::           ||.|        |.::.:..:||   :|::   |...|...
 Frog   266 EEARHREETLKRD-----------FERWREEERSKRQDEMDKIMQQFHSQLQEVTLKNSTYESRF 319

  Fly   304 HALEQSKQASASTPPLEDRVATPCLEDLERILTEKVAEIGKVSAHRLEEVVYHLEEGYKEKLGAL 368
            |.||.......|...|.|        :.||:..:::.:    ....|:|.:...:.|:|:||..:
 Frog   320 HNLESKNSMVPSLGNLAD--------EEERLELKRLQQ----GMRNLKEELEQQQSGWKKKLKEV 372

  Fly   369 ERELKQLSVQKVQPEPVQTVPVASKIPKPVVRKEETNIDRIRKQVESEFLKQKHDDDTYSIEEAP 433
            :|:                         ..|.|:|.       |.|:|.||.....|..::::
 Frog   373 QRD-------------------------HGVEKQEL-------QYENERLKASMTRDQQAVDQ-- 403

  Fly   434 RKGSEKPFPQLVTQVQVVEKEQPSAGSSDSNPTYTKSPREPAPNKQETKEATDV---SDSLSQEE 495
                     |:..|:|.::.:.........|...|   .|.....:|..:...|   :.::..|.
 Frog   404 ---------QVTKQMQSLKSQIKEKNKLIQNYELT---IEDLSRSREVPQVAQVVLPAGAIKDEA 456

  Fly   496 TENEEERSLTEEEGTDVPTSGSEAAREDPTPKTIKPSGRIIKSPQKPLTRKDARKMVNRKLMSHG 560
            :|:|.:.||::...|      .:..|.:|.         .||.     .|....:.:..||.|.|
 Frog   457 SEDELDYSLSQNLKT------IDDLRRNPD---------FIKQ-----FRPILEQTLIEKLESLG 501

  Fly   561 FDMKSKGISHNSLKRVNSEL-TEHRNKLKLQHPHFYATRNRIRKFVEKLCSAKFSERAEMLLKHK 624
            ....:|||:.::.|.:.:.| |:...|:: :||.....|   .|.|:||
 Frog   502 VKKGAKGINSSAHKNLIAVLQTQLEQKIR-KHPEIQTIR---AKMVKKL---------------- 546

  Fly   625 SPLKPMEVPGKGIPRSAISEKSEEDIASSQGEEQTDEQTDSSEQQTRSPSPQRLV----SRDFKA 685
                                  .:.:...|..|:|: |..||:..::.||.||:|    ....:|
 Frog   547 ----------------------TQKVKQWQKNEETN-QYKSSQLSSQKPSNQRIVPPSEEETSQA 588

  Fly   686 RLEEILVKPAATIRGASKSSLSSRPVPLPRKR 717
            |...:|:.       .|:.|.:..|||.||.:
 Frog   589 RSRNVLMV-------GSQQSPNRAPVPFPRTK 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	30/135 (22%)
		SMC_N	182..>457	CDD:481474	54/288 (19%)
dzip1l	XP_012826036.1	Dzip-like_N	51..171	CDD:433498	29/129 (22%)
		Smc	<128..>451	CDD:440809	82/426 (19%)
		Pneumo_att_G	<543..737	CDD:114270	24/117 (21%)