Protein Alignment DZIP1 and Dzip1l

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_006511535.1
• Gene: Dzip1l / 72507
• MGIID: 1919757
• Length: 800
• Species: Mus musculus
• Alignment Length: 760
• Identity: 157/760 - (20%)
• Similarity: 290/760 - (38%)
• Gaps: 207/760 - (27%)

  Fly     6 KYPQMVRE------------TGFKLRQYRDGPLDWRLMGSYETERILREQNFELVDKALTHLSEA 58
            :||....|            ..||.:..|:. :|||.:.:.:.:|:.||.:...:.:.:..::..
Mouse    28 QYPAATAEGLSGPLSGAYTLPAFKFQPRRES-IDWRRISAVDVDRVARELDVATLQENIAGVTFC 91

  Fly    59 PLGTVLETHI---LDSGIAKYFVMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLS 120
            .|...:..|.   :|..:.|...::|..|:||:.|:..|...|..|:          |.|:.||.
Mouse    92 NLDGEVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQDCLSASVAQLE----------ARLQASLG 146

  Fly   121 ESNNEVVQLHKRITQIEAIRE----------------------VVYPCHLCTKNFISNEALNVHI 163
            :......:|.::..:::.:||                      ..:.||||.|.|::...|..||
Mouse   147 QQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQTSAHSYHTCHLCDKTFMNATFLRGHI 211

  Fly   164 GRKHRVASPPSLTSATGKEKDRDKATDV--HLINTIKM---ELEI-------KQLKERLNAAERN 216
            .|:|      :..:..||:|......:|  .|...:|.   |||.       :|::|...|.:|.
Mouse   212 QRRH------AGMADVGKQKQEQPLGEVLEELRAKLKWTQGELEAQREAERQRQVQELEMARQRE 270

  Fly   217 I-----------KERSTGSKRVSPRQ-----EQRHVGIQSNLAEPKEK--------DEDSGEARQ 257
            :           ||||.....:...:     |.:.|..|::..|.|.|        :...|..|.
Mouse   271 MEAKKKFDEWKEKERSKLYGEIDKLKQLFWDEFKTVANQNSTLEEKLKALQSYSMTESHLGSLRD 335

  Fly   258 SEASER---KEQLTGLAERLS-NFEEWQTQLKQSNEQ------FIQDINKRLEGLSHALEQSKQA 312
            .|:.||   .:::..|.|::. ...||:.::|..:|:      .:|:.|:||. :|.:.:|.|.|
Mouse   336 EESEERLKHAQEVQALQEKMEVQKTEWKRKMKALHEERAAERRQLQEENERLH-VSLSQDQKKAA 399

  Fly   313 SASTPPL-----------------EDRVATPCL---------------------EDLERILTEKV 339
            :.|...:                 |:.:.|..|                     |:||..|.|:.
Mouse   400 AQSQRHINALRAQLQEQARLIESQEETIQTLSLRKVEEVQEMPKAVATEEDSSEEELEASLEERQ 464

  Fly   340 AEIGKVSAHR-----LEEVVYHLEEGYKEKLGAL--ERELKQLSVQKVQP-EPV---QTVPVASK 393
            .:...::|.|     |::....||:..:|||..|  :|:.|.:|.|.|:. ||:   |...:|..
Mouse   465 EQRKVLAALRKNPTWLKQFRPILEDTLEEKLEGLGIKRDTKGISAQTVRRLEPLLRTQREQIARS 529

  Fly   394 IPK-PVVRKEETNIDRIRKQVESEFLKQKHDDDTYSIEEAPRKGSE--------KPFPQLVTQVQ 449
            ..: |.:|      :::.|:|.|. :||:.:..|....:.|.|...        :|..:.:|...
Mouse   530 FREFPSLR------EKLNKEVSSR-VKQRWESTTQPDGQPPVKSQRVTLATREVRPKTRTLTVAL 587

  Fly   450 VVEKEQPSA----GSSDSNPTYTK------SPREPAPNKQETKEATDVSDS---LSQEETENEEE 501
            ..:..:||.    |.|...|..|:      .||...|:.......:.:|.:   .|:||.|.:..
Mouse   588 PSKPAEPSTPTLQGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGSGLSSTPPFSSEEEPEGDVV 652

  Fly   502 RSLTEEEGTDVPTSG-----------SEAAREDPTPK-----TIKPSGRIIKSPQKPLTRK---D 547
            :.::.:....:|.|.           ||.:.|...|.     .:..||.:::|..|.|.::   .
Mouse   653 QRVSLQPPKVLPRSAAKPEDNWGWSDSETSEESAQPPGKGSGGLASSGTLVQSIVKNLEKQLETP 717

  Fly   548 ARKMVNRKLMSHGFDM---KSKGISHNSLKRVNSELTEHRNKLKL 589
            |:|      .|.|.:|   .:..:...|.....|:|:|..:.:::
Mouse   718 AKK------PSGGVNMFLRPNAALQRASTPARKSQLSEDESDVEI 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	26/119 (22%)
		SMC_N	182..>457	CDD:481474	79/378 (21%)
Dzip1l	XP_006511535.1	Dzip-like_N	50..170	CDD:433498	28/130 (22%)
		PTZ00121	<142..505	CDD:173412	77/369 (21%)
		PTZ00249	<537..>690	CDD:140276	31/159 (19%)