Protein Alignment DZIP1 and dzip1

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_073808864.1
• Gene: dzip1 / 402875
• ZFINID: ZDB-GENE-040526-1
• Length: 907
• Species: Danio rerio
• Alignment Length: 826
• Identity: 180/826 - (21%)
• Similarity: 332/826 - (40%)
• Gaps: 215/826 - (26%)

  Fly    16 FKLRQYRDGPLDWRLMGSYETERILREQNFELVDK---ALT---------HLSEAPLGTVLETHI 68
            :|.|..|:. :|||.:.:.:.:|:..|.:|:.:.:   |:|         |..::|
Zfish    65 YKFRSRREN-VDWRRINAVDVDRVACEMDFQALQEHINAVTFCSVEGERCHRCQSP--------- 119

  Fly    69 LDSGIAKYFVMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLSESNNE---VVQLH 130
            :|..:.|.|.::|..::||:    :..:|::...:|   |:|.:      |:|:...   .|||.
Zfish   120 VDPALIKLFRLAQLTVEYLL----HSQDCLSISLQA---AEERL------LAEAREREQICVQLQ 171

  Fly   131 KRITQIEAIREVV----------------------YPCHLCTKNFISNEALNVHIGRKHRVASPP 173
            |:....:|::|.:                      :.|..|.|.|::...|..|:.|:|     |
Zfish   172 KKTQDAKALKEELKQRKKIIASQQAMFSAGISANYHKCQHCEKAFMNASFLQSHMQRRH-----P 231

  Fly   174 SLTSATGKEKDRDKATD-VHLINTIKMELEIKQLKERLNAAERNIKERSTGSKRVSPRQE----Q 233
            |       |.|....|| ...|.|:|::.||.:|:|:|...   ..:..|..|..:.:||    |
Zfish   232 S-------EFDMKLMTDNQKKIQTVKLQDEINKLQEQLTLV---TSQMETQQKDYTAKQEKELIQ 286

  Fly   234 RHVGIQSNLAEPKEKDEDSGEARQSEASER-KEQLTGLAERLSNFEEWQTQLKQSNEQFIQDINK 297
            |....:..|...||:::....::..|..:. :..:..:.:|..|.|....:|:|.|.|
Zfish   287 RQEEFKRQLEIWKEEEKMRMNSKIDEVKQACQRDMDSMHQRNRNLETELLKLQQKNIQ------- 344

  Fly   298 RLEGLSHALEQSKQASASTPPLEDRV----------------ATPCLEDLERILTEKVAEIGKVS 346
              |.: .:::....||||....::.|                .....||.:|   ||.....::|
Zfish   345 --ESM-QSVQTQPNASASNEHWQEVVKLQQKLHKQEVKWTGKMQKMKEDHDR---EKSLSPTRLS 403

  Fly   347 AHR-LEEVVYHLEEGYKEKLGALERELKQLSVQKVQPEPVQTVPVASKIPKPVVRKEETNIDRIR 410
            .|| |:|.:..:.....|.:....|::::|| .::| |..|.:               |:.::..
Zfish   404 VHRQLQEELCKVSSAVSEGMEESRRQVQELS-HRLQ-EQQQII---------------TSQNKQM 451

  Fly   411 KQVESEFLKQKHDDDTYSIEEAPRKGSEKPFPQLVTQVQVVEKEQPSAGSSDSNPTYTKSPREPA 475
            ||:.|:       ..|.:::   |:|...|.|:  |:.:||..||       ||..:...|  ..
Zfish   452 KQISSK-------PPTITVQ---REGVSTPSPE--TKAKVVVSEQ-------SNSVHKLDP--IV 495

  Fly   476 PNKQETKEATDVSDSLSQEETENEEERSLTEEEG--TDVPTSGSEAAREDPTPKTIKPSGRIIKS 538
            ...:|.|:::.:|:|.::..:..:|.:.|.:..|  .|:..:......:......||....:.|:
Zfish   496 ELSEEDKDSSSISESPTENRSWQKEVQELLKNPGLRRDMRLAAQHNLDDRLQSLGIKGVSGLSKN 560

  Fly   539 PQK-PLTR--KDARKM-----VNRKLMSHGFDMKSKGISHNSLKRVNSELTEHRNKLKLQHPHFY 595
            ..| .:|:  .|.||.     |.|:.:        |.|||...:||....||...|.|| |....
Zfish   561 LYKSSMTQIISDRRKKLEEDPVYRRAL--------KEISHKLEQRVKERNTEQPVKPKL-HEQVV 616

  Fly   596 ATRNRIRKF---VEKLCSAKFSE---------RAEMLLKHK--SPLKPMEVPGKGIPRSAISEKS 646
            .:|.|...|   |.::.|...|:         |:...:.||  :||:....|    |.|     |
Zfish   617 QSRPRSSSFPSTVTRVMSGPASKQQRTPQPVPRSRSNVPHKTSTPLQHRRTP----PFS-----S 672

  Fly   647 EEDIASSQGEEQTDEQTDSSEQQTRSPSPQR---LVS-------RDFKARLEEILVKPAATIRGA 701
            :||  ||:.||:.:|:.:||:::  ||..|:   ||:       ...|.:.....|:||..:..|
Zfish   673 DED--SSEEEEEEEEEEESSDEE--SPQMQKKTVLVNSSTAKAQNTAKTQSTAQSVRPAVALTSA 733

  Fly   702 SKSSLS----------SRPVPLPRKRVMFNTTEDGKSFNDSDDNLK 737
            ..::::          |....:...::..:|.::|...|.:..|:|
Zfish   734 EPTNVTTLSDSDWSDGSEMEEINLSQLHKHTDQNGNLKNVTHSNVK 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	29/131 (22%)
		SMC_N	182..>457	CDD:481474	66/297 (22%)
dzip1	XP_073808864.1	None