Protein Alignment DZIP1 and Dzip1

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_063130566.1
• Gene: Dzip1 / 364475
• RGDID: 1307701
• Length: 885
• Species: Rattus norvegicus
• Alignment Length: 807
• Identity: 164/807 - (20%)
• Similarity: 273/807 - (33%)
• Gaps: 224/807 - (27%)

  Fly    24 GPL------------DWRLMGSYETERI--------LREQNF-----ELVDKALTHLSEAPLGTV 63
            |||            |||.:.:.:.:::        |:|...     :|.|:...|....
  Rat    75 GPLPFFQFRPRLESVDWRRLSAIDVDKVAGAVDVLTLQENIMNITFCKLEDEKCPHCQSG----- 134

  Fly    64 LETHILDSGIAKYFVMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLSESNNEVVQ 128
                 :|..:.|...::|..|:|||..:.:|...:..::|          .||.||.:.......
  Rat   135 -----VDPVLLKLIRLAQLTIEYLMHSQEFLTSQLNLVEE----------RLRLSLMDYEQSKQL 184

  Fly   129 LHKRITQIEAIRE--------------------VVYPCHLCTKNFISNEALNVHIGRKHRVASPP 173
            |.|:..:|:.::|                    ..|.||||.|.|::...|..||.|:|
  Rat   185 LTKQAGEIKLLKEECKRRKKMLSTQQLMIEAKASYYQCHLCDKAFMNQAFLQSHIQRRH------ 243

  Fly   174 SLTSATGKEKDRDKATDVHL-----INTIKMELEIKQLKERLNAAERNIKERSTGSKRVSPRQEQ 233
                          ..|.||     ..|.:::.||..|||:|......::.          .|..
  Rat   244 --------------TEDSHLEYNTKAQTDRLQKEIDMLKEQLQLTRTQLES----------AQHS 284

  Fly   234 RHVGIQSNLAEPKEKDEDSGEARQSEASERKEQLTGLAERLSNFEEWQTQLKQSNEQFIQDINKR 298
            ..|....:....|.|:||..:.......|.||:|         .||    :::..|.|:::. |:
  Rat   285 HAVRFSKDYEMQKIKEEDFLKLFDRWKEEEKEKL---------LEE----MEKVKEMFMREF-KK 335

  Fly   299 LEGLSHALEQSKQASASTPPLEDRVATPCLEDLERILTEKVAEIGKV-SAHRLEEVVYHLEEGYK 362
            |...:.|||..                  |.:::|...:..:.||.: .||.|.|......:.::
  Rat   336 LTSKNSALEYQ------------------LLEIQRSNIQIKSNIGTLRDAHELREDHLPYPQDFQ 382

  Fly   363 EKLGALERELKQLS--VQKVQPEPVQTVPVASKIPKPVVRKEE----TNIDRIRKQVESEFLKQK 421
            ..|..|:.:..:.|  .|.:..|.               .||:    ::|:::|    |..:|..
  Rat   383 NMLQLLDSQASKWSDRFQVLNEEH---------------SKEKGQLLSHIEKLR----SSMMKDL 428

  Fly   422 HDDDTY---SIEEAPRKGSEKPFPQLVTQVQVV----EKEQPSAGSSDSNP--TYTKSPREPAPN 477
            ..|:.:   .:||..:|..|:. ..::||.|.:    .|...|.......|  ..|..|:..|..
  Rat   429 SADNVFYKRRVEELGQKLQEQN-EVIITQKQQIREFASKPYHSVNEMKGTPLTRQTLEPKSAALT 492

  Fly   478 KQETKEATDVSDSLSQ-----------------EETENEEERSLTEEEGTDVPTSGSEAAREDPT 525
            ......||...|..|.                 .|..:|||:....|:.|:..|...:....:||
  Rat   493 TPMNASATQNLDGTSNLTMVHEQVFSSHILEPIAELSSEEEKGRENEQKTNKKTHVRKTPNTNPT 557

  Fly   526 PKTIKPSGRIIKSPQKPLTRKDARKMVNRKLMSHGFDMKSKGISHNSLKRVNSELTEHRNKLKLQ 590
            ||.:               |.:..|.:..||.|.|.....:||....|.|....:...|:.|..|
  Rat   558 PKEL---------------RTNLEKELGNKLRSFGISENIQGIPCEILNRSLKAMQVARHDLAKQ 607

  Fly   591 HPHFYATRNRIRKFVEKLCSAKFSERAEML--LKHKSPL---KPMEVPGKGI---PRSAISEKSE 647
            .|..    .:||:.:|.....|..|||...  .:|..|:   .|.||| |..   |||....:.:
  Rat   608 VPDI----QQIRENLEHQLICKMGERASHSSDRRHAPPMASFPPEEVP-KATQLPPRSRPLVRQK 667

  Fly   648 EDIASSQGEEQTDEQTDSSEQQTRSPSPQRLVSRDFKARLEEILVKPAATIRGASKSSLSSRPVP 712
            ..........:..:.|..|....|.|:.:.......:...||..::     ...|...|.::|..
  Rat   668 TMFTDKASAPKLKKNTKESHFLRRFPATKTPPFSSEEEPEEEGFMR-----AHRSPDVLPTQPPK 727

  Fly   713 LPR----KRVMFNTTE--DGKSFNDSD 733
            ..|    :|.:.:.|:  :|...:|||
  Rat   728 NKRSNFGRRAVRSDTDWTEGSEMDDSD 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	26/133 (20%)
		SMC_N	182..>457	CDD:481474	57/293 (19%)
Dzip1	XP_063130566.1	None