Protein Alignment DZIP1 and Dzip1l

DIOPT Version :10

• Sequence 1: NP_651263.1
• Gene: DZIP1 / 42921
• FlyBaseID: FBgn0039201
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: XP_006243688.1
• Gene: Dzip1l / 315952
• RGDID: 1311430
• Length: 777
• Species: Rattus norvegicus
• Alignment Length: 855
• Identity: 160/855 - (18%)
• Similarity: 303/855 - (35%)
• Gaps: 276/855 - (32%)

  Fly    16 FKLRQYRDGPLDWRLMGSYETERILREQNFELVDKALTHLSEAPLGTVLETHI---LDSGIAKYF 77
            ||.:..|:. :|||.:.:.:.:|:.||.:...:.:.:..::...|...:..|.   :|..:.|..
  Rat    24 FKFQPRRES-IDWRRISAVDVDRVARELDVATLQENIAGVTFCNLDREVCNHCRQPVDPVLLKVL 87

  Fly    78 VMSQYAIQYLMCCRTYLDECVTDLKEAHTTAQEEIATLRKSLSESNNEVVQLHKRITQIEAIRE- 141
            .::|..|:||:.|:..|...|..|:          |.|:.||.:......:|.::..:::.:||
  Rat    88 RLAQLIIEYLLHCQDCLSASVAQLE----------ARLQASLGQQQRGQQELGRQADELKGVREE 142

  Fly   142 ---------------------VVYPCHLCTKNFISNEALNVHIGRKHRVASPPSLTSATGKEKDR 185
                                 ..:.||||.|.|::...|..||.|:|      :..:..||:|..
  Rat   143 SRRRRKMISTLQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRH------AGMAEVGKQKQE 201

  Fly   186 DKATDV--HLINTIKM---ELEIKQLKERLNAAE--RNIKERSTGSKRVSPRQEQRH-------- 235
            .:..:|  .|...:|.   |||.::..||...|:  ..|::|...:|:.....:::.
  Rat   202 QQLGEVLEELRAKLKWTQGELEAQREAERQRQAQELEMIRQREIEAKKKFDEWKEKERSKLYGEI 266

  Fly   236 -------------VGIQSNLAEPKEK--------DEDSGEARQSEASER---KEQLTGLAERLS- 275
                         |..|::..|.|.|        :...|..|..|:.||   .::|..|.|::.
  Rat   267 DKLKQLFWDEFKTVANQNSTLEEKLKVLQSYSMTESHLGSLRDEESEERLKHAQELQALREKMDI 331

  Fly   276 NFEEWQTQLKQSNEQ------FIQDINKRLEGLSHALEQSKQASASTPPLEDRVATPCLEDLERI 334
            ...||:.::|..:|:      .:|:.|:||. ::.:.:|.|.|:.|...:....|.  |::..|:
  Rat   332 QKTEWKRKMKALHEERAAERRQLQEENERLH-VTLSQDQKKAAAQSQRHINALRAQ--LQEQARL 393

  Fly   335 LTEKVAEIGKVSAHRLEEVVYHLEEGYKEKLGALERELKQLSVQKVQPEPVQTVPVASKIPKPVV 399
            :..:...|..:|..|:|||                                      .::||.||
  Rat   394 IESQEETIQTLSFRRMEEV--------------------------------------QEVPKAVV 420

  Fly   400 RKEETNIDRIRKQVESE---------------FLKQKHD--DDTYSIEE-----APRKGSEKPFP 442
            .:|:::.:.:...:|.:               :|||...  :||  :||     ..::|::....
  Rat   421 TEEDSSEEELEASLEEQQEQRKVLAALRNNPAWLKQFRPILEDT--LEEKLEGMGIKRGTKGISA 483

  Fly   443 QLVTQVQVVEKEQPSAGSSDSNPTYTKSPREPAPNKQETKEATDVSDSLSQEETENEEERSLTEE 507
            |.|.::                        ||....|..:.|....:.||..|..|:|..|..::
  Rat   484 QTVRRL------------------------EPLLRTQREQTARSFREFLSLREKLNQEVSSRAKK 524

  Fly   508 --EGT----------DVPTSGSEAAREDPTPKTIKPSGRIIKSPQKPLTRKDARKMVNRKLMSHG 560
              |||          .|.:..:..|..:..|||...:..:...|.:|.|      ...|...|||
  Rat   525 RWEGTAVVPQPDGQPPVKSQRTTLATREVRPKTRTLTVALPSKPAEPST------STPRGHSSHG 583

  Fly   561 FDMKSKGISHNSLKRVNSELTEHRNKLKLQHPHFYATRNRIRKFVEKLCSAKFSERAEMLLKHKS 625
                      ..|.:|::.:                .|.|:                     |..
  Rat   584 ----------PGLTQVSTPI----------------PRPRV---------------------HGP 601

  Fly   626 PLKPMEVPGKGI---PRSAISEKSEEDI--------------ASSQGEEQ---TDEQTDSSEQQT 670
            ...|:. ||.|:   |..:..|:.|.|:              ::.|.|:.   :|.:|  ||:..
  Rat   602 SSTPVS-PGPGLSSTPPFSSEEEPEGDVVQRVSLQPPKVLPRSAPQPEDNWGWSDSET--SEESA 663

  Fly   671 RSP--------SPQRLVS---RDFKARLEEILVKPAATIRGASKSSLSSRPVPLPRKRVMFNTTE 724
            :||        |...||.   ::.:.:||....||:..:....:.:.:.:....|.::...:..|
  Rat   664 QSPGKGSDGLASSATLVQSMVKNLEKQLETPAKKPSGGVNMFLRPNTALQRSSTPARKTQLSEDE 728

  Fly   725 DGKSFNDSDD 734
            .....:..:|
  Rat   729 SDLEISSLED 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DZIP1	NP_651263.1	Dzip-like_N	16..133	CDD:433498	26/119 (22%)
		SMC_N	182..>457	CDD:481474	63/342 (18%)
Dzip1l	XP_006243688.1	Dzip-like_N	24..144	CDD:433498	28/130 (22%)
		Smc	<110..>392	CDD:440809	61/300 (20%)
		PTZ00249	<511..>667	CDD:140276	39/211 (18%)