DRSC/TRiP Functional Genomics Resources

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Protein Alignment nAChRalpha1 and LOC1275309

DIOPT Version :10

Sequence 1:NP_001262916.1 Gene:nAChRalpha1 / 42918 FlyBaseID:FBgn0000036 Length:597 Species:Drosophila melanogaster
Sequence 2:XP_314547.3 Gene:LOC1275309 / 1275309 VectorBaseID:AGAMI1_003422 Length:332 Species:Anopheles gambiae


Alignment Length:115 Identity:34/115 - (29%)
Similarity:47/115 - (40%) Gaps:36/115 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 ATGGLANPDA----------KRLYDDLLSNYNRLIRPVGNNSDRLTVKMGLRLSQL-IDVNLKNQ 69
            :|.|.|..|.          :||.|.|| ...|.|.|..|.|       |:::||: |...:.:|
Mosquito   197 STNGTALIDGNELEQEFDGKQRLLDHLL-GVPRWIDPPVNFS-------GVQISQMYIQGFVYDQ 253

  Fly    70 IMTTNVWVE------QEWNDYKLKWNPDDYGGV----DTLHVPSEHIWLP 109
              |||: ||      ..|.|.:.:||..|:...    |..|:    ||.|
Mosquito   254 --TTNL-VELSGAMGLSWKDPRYRWNASDFDNTTVVGDVCHL----IWTP 296

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
nAChRalpha1NP_001262916.1 LGIC_ECD_nAChR_proto_alpha-like 24..242 CDD:349832 31/107 (29%)
LIC 27..530 CDD:455710 30/94 (32%)
Cys-loop 149..163 CDD:349832
LOC1275309XP_314547.3 None
Blue background indicates that the domain is not in the aligned region.

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