Protein Alignment CG6454 and LOC1281699

DIOPT Version :10

• Sequence 1: NP_651249.2
• Gene: CG6454 / 42904
• FlyBaseID: FBgn0039187
• Length: 1569
• Species: Drosophila melanogaster
• Sequence 2: XP_061503267.1
• Gene: LOC1281699 / 1281699
• VectorBaseID: AGAMI1_009815
• Length: 1068
• Species: Anopheles gambiae
• Alignment Length: 1609
• Identity: 612/1609 - (38%)
• Similarity: 781/1609 - (48%)
• Gaps: 582/1609 - (36%)

  Fly     1 MPGKVGVKIKAARNLPVMDKSSETTDAFVEIKLASVTHKTDVFRKSLNPTWNTDWFRFEVDDAEL 65
            |||||.||:.|.|||||||:||:||||||||||.:||:||||.||:|||.||::|:.|||:||||
Mosquito     1 MPGKVKVKVLAGRNLPVMDRSSDTTDAFVEIKLGNVTYKTDVCRKTLNPHWNSEWYTFEVEDAEL 65

  Fly    66 QDEPLQIRLMDYDTYSANDAIGKVNISLNPLCLESSSQAVHGKGTVLSGWIPVFDTMHGIRGEIN 130
            |||||||||||||||:||||||||.|:|:|| |.|::::..|||:::|||:||:||:||:|||||
Mosquito    66 QDEPLQIRLMDYDTYTANDAIGKVYINLSPL-LHSTTKSRTGKGSIMSGWLPVYDTIHGVRGEIN 129

  Fly   131 VIVKVDLFSDVNKFRQSSCGIPFFHSQCVPFGYRAQVIHGFVEELVVNDDPEYQWIDKIRTPRAS 195
            ||||||||:|.|||||||||:.||||..:|:||...:.|||||||||||||||||||||||||||
Mosquito   130 VIVKVDLFTDFNKFRQSSCGVLFFHSSNIPYGYSIAMYHGFVEELVVNDDPEYQWIDKIRTPRAS 194

  Fly   196 NEARQVVFLKLSGQVQRRMGLKAINMGANAVIGYTQCFDLEGDVGVVARGIGTAVTLIKDTSTSQ 260
            |||||:.|:|||.||||::|:|||.|||||||||.||:|||||||||||||||||:|.|...:..
Mosquito   195 NEARQLAFMKLSAQVQRKIGIKAIEMGANAVIGYMQCYDLEGDVGVVARGIGTAVSLTKINESFS 259

  Fly   261 PNSADVALIEELTQKYLDFLNCAGASNSSLPLSGRTPQYRLNIYREPSSSAPSSAAAAAAATMFY 325
            .:..:..|:||
Mosquito   260 QHIGEEILVEE------------------------------------------------------ 270

  Fly   326 LESASSDTEDAELMQNLIRQEDERGDRNREKKLRHRMRRLTLSSSKIFSQKYATLIRRIEPKIPE 390
                                              |:
Mosquito   271 ----------------------------------HK----------------------------- 272

  Fly   391 NATQSLSSIFGGATAATSSFRRRRKSRFAASTSKSSIPPFITRSISSDSNVRPGRMPIKSFLTVP 455
                                                                             
Mosquito   273 ----------------------------------------------------------------- 272

  Fly   456 GLMEYQENTRSAPDLPGDEFQARTRPTSNYSTESEDSLQLDLEIGPPESNAEDSPEEEEDLQDNW 520
                                                                             
Mosquito   273 ----------------------------------------------------------------- 272

  Fly   521 IKPGETRSCENSQQDLGPSHHNLLDDLKGFSRRLQKMMHLSPKSSDIEKKLPFVPSLERKPYYSS 585
                                                                             
Mosquito   273 ----------------------------------------------------------------- 272

  Fly   586 QPELPSCSNDCLVSNLSGSSSMLQLNFLPSYGKTMQRSASLNHLVAPDTPVPPNTLLLKAPELRV 650
                           |||||
Mosquito   273 ---------------LSGSS--------------------------------------------- 277

  Fly   651 CPSTPTPTQSNLVVFDYNNSPCLTQLDQSVNISNSTNHSNHNNESSLLAPFAIRQQQPPRVIRSS 715
                           |:.:                                      |||
Mosquito   278 ---------------DFGD--------------------------------------PPR----- 284

  Fly   716 SELQQQPCSTGAAASTGPSNIPTTVEGSSPNLKRFASPVSSSRLKLTPSPSKSGISATTNADSAS 780
                      .|.|..|.||...|  |:||.  :..:|:.:|.|
Mosquito   285 ----------RALAIGGESNNHAT--GNSPT--KLGTPIVNSLL--------------------- 314

  Fly   781 TSTASTATTMVPATVGEICRRSSDSDLSVTPKGNSICVASERLVAATAMMRLTQPTVGAKPGTAA 845
                :..|..||     |||||||||||:||||:| |...:.:    .::|    ..||..|.|.
Mosquito   315 ----TKDTVCVP-----ICRRSSDSDLSITPKGSS-CPLDKSI----GIVR----NYGANNGNAK 361

  Fly   846 -------DSLDMLEYPFLTMTKYPTGFILHLGATVAARSVKLLERVPNPDEPEVRDSWWTELRME 903
                   |.|:||||||.||||||.|.|.::||||.|||||||||||||:|||.|||||.|:|.|
Mosquito   362 SIMIMNYDMLEMLEYPFFTMTKYPPGIIRYIGATVTARSVKLLERVPNPNEPETRDSWWNEIRTE 426

  Fly   904 IRSHARSLGCNVVLGYAETTTISDDVCVLSATGTAAVINMVFNRSVSQTDIFTMSKATASVAA-- 966
            :|||||||||||:|||.|.|||.||:|||||||||||||:.|...:...|....:.|.....:
Mosquito   427 VRSHARSLGCNVILGYVEQTTIDDDICVLSATGTAAVINLQFGSDMWMADASLNASADGGADSSQ 491

  Fly   967 ----MTNSVE--------DGNGSTAGDTSIGKDS--GSLGTGNSSGGKRYGLPPLNGPRNACAIC 1017
                ||:|::        .|:.....:|..|:.:  |..|:|||.                |.:|
Mosquito   492 AKEHMTSSLDRQDFDRECSGSREQTPNTIEGEGTYDGPSGSGNSK----------------CTMC 540

  Fly  1018 HIPYNLSSVPFNVKMKKCAVCRKGRVPDVLLATLEVPEFMQVTGRGCFMQAQVVRAKRDLRAELN 1082
            |:||:|.||.|.:...||.:|:.|.|||||:.|:|:|:.:.|:|||..:||...|.||||:.|.|
Mosquito   541 HVPYSLGSVNFRINAVKCFMCKNGIVPDVLITTIEIPDGVPVSGRGSLIQAHTCRQKRDLKGEAN 605

  Fly  1083 AKEISDGLPFLEYELHRVLINKLKAKGMNAIFGLRTQVAIGERMIALIATGTALFLTALPVPQVP 1147
            .|||||.|||||||||::|:||||.||||||||||:.:.|||:.|||||||||::|||||.|.:|
Mosquito   606 GKEISDALPFLEYELHKLLVNKLKIKGMNAIFGLRSNITIGEKTIALIATGTAVYLTALPKPLLP 670

  Fly  1148 KIVAGNSWTDKQKLNELQKKLQETFERNQEIYQLKSL-DPDLAANVGGVPSTGASGDKQSDTDDS 1211
            :||..:|:.|::|:.||||.:|...|:|.:.|||:.: |.|......|  :||.:..:
Mosquito   671 QIVDSSSFPDERKIQELQKMVQNIVEQNIQAYQLQCVYDSDTEQAPAG--ATGVASSR------- 726

  Fly  1212 DEEEMNEIDLNCGNKELCVLEVDDIEDLEIISLLMEP-YPPEGFHVVNTQQVPGMLE--MDTVKN 1273
            :|.:..|:||.|..|..||||:|||.||::::...|| ..|:||:|.|.|.:||:..  :|.||.
Mosquito   727 EERDGKELDLVCMQKSACVLELDDIIDLDLLTFEKEPEIAPDGFYVANLQTMPGISTDVLDNVKQ 791

  Fly  1274 LQMFTQVWRARL--EVGQSVNGFPKHFQRLLQTIYFKLRTMIPCAICDLRFRLDLPETDQIQLLV 1336
            .|||||||||:|  .:..:.....|.||.||:.||:|||:|.||.:||||::||.||||:||::|
Mosquito   792 FQMFTQVWRAKLPYTLQHTTRNLNKRFQGLLKLIYYKLRSMRPCVLCDLRYKLDFPETDEIQIVV 856

  Fly  1337 TGMAMGLSD-ANRMKYRGRGRPAQQQQAPQQQNGYHDGTVHATQSQPELNGKRMLQEEDYIFPLD 1400
            :||.:.|.| ..|:|   |....|....|......|..:|           .|...:::.:|.||
Mosquito   857 SGMTLALGDGTTRLK---RKCSTQNHHTPGPSPSVHSSSV-----------ARSSNDDEMMFSLD 907

  Fly  1401 EDQMVDTP----TPTSTAIPPFGMSSFKMRKTSPSRLNNLVSGLPSTGVKPLNVGS-----VQRS 1456
            ||.| ||.    .|.||.:|.. :.|||.|                 |.|.:...|     :.||
Mosquito   908 EDSM-DTSGPPVAPASTPVPSI-VKSFKSR-----------------GTKAMTAASSYHSKINRS 953

  Fly  1457 -RYFPLRDRYGVDVTPLSFIPGGRIDKYLGNLNFFFIRESTSIRENGGISGFVHGFITELLAVVR 1520
             :..||:|.||||:|.||:||||:|:|||||||||||||.|||||:|||.||||.||:|:|::||
Mosquito   954 GKMIPLKDGYGVDITTLSYIPGGKIEKYLGNLNFFFIRECTSIRESGGICGFVHSFISEVLSIVR 1018

  Fly  1521 AHIASLGGNAMVSFYITELMLFDNQHKNQGQCLISIGGDAVYVSYHADD 1569
            ||:.|||||||::||:.:|.|.||.||||||||||:|||.|:||:|.|:
Mosquito  1019 AHVTSLGGNAMIAFYLNDLTLLDNVHKNQGQCLISVGGDVVFVSFHKDE 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6454	NP_651249.2	C2_KIAA0528-like	5..121	CDD:176070	81/115 (70%)
LOC1281699	XP_061503267.1	None