Protein Alignment twin and Angel1

DIOPT Version :10

• Sequence 1: NP_732964.1
• Gene: twin / 42880
• FlyBaseID: FBgn0011725
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: XP_017449718.1
• Gene: Angel1 / 362765
• RGDID: 1306238
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 606
• Identity: 130/606 - (21%)
• Similarity: 215/606 - (35%)
• Gaps: 200/606 - (33%)

  Fly    96 LTSLRTLDLSSNKLRSLPAELGELIQLRELLLNNN--FLRVLPYEIGKLF---HLVILGLMGNPL 155
            |:.||..|   |..:..|..|||     |.|..:.  ....:|.:.|..:   .::.:|.|....
  Rat   137 LSDLRAAD---NLDQPFPEVLGE-----EPLAEDEGPLWAAVPVQTGPQYADCAVLPMGAMAAEQ 193

  Fly   156 QKE-----FMNIYNEPNGTQKLLTYMLDNLSFTVNPPPQ---------RPWLPLAKPNKTR---- 202
            .:|     ..:|..||...::...:..:.|. .:.|||.         |.|...:.....:
  Rat   194 WEEDPAMVAWSIAPEPMPQEETSMWPFEGLE-QLQPPPMEIPYHEILWREWEDFSTQPDAQGLEA 257

  Fly   203 ---PACIFTVMCYNVLCD--KYATRQMYGYCPSWALCWEYRKKSIIDEIRHYAADIISLQEIETE 262
               |...||:|.||:|..  ...:.::|.:|....|.|.||..:::.|.:|:..||:.|||::.:
  Rat   258 GDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQED 322

  Fly   263 QFYHFFLPELKNDGYEGIFSPKSRAKTMSELERKYVDGCAIFFRASKFTLIKESLIEFNQLAMAN 327
            .::....|.|:..|:...:..::..||         ||||:.::.::|.|:..|.:|:.:..:
  Rat   323 HYWEQLEPSLRMMGFTCFYKRRTGCKT---------DGCAVCYKPTRFRLLCASPVEYFRPGL-- 376

  Fly   328 AEGSDNMLNRVMPKDNIGLAALLKVKENAWEPM--SEVTQIS-QPLLVCTAHIHWDPEFCDVKLI 389
                 .:|||    ||:||..||       :|:  ..:.|:| .||.|...|:.::|...||||.
  Rat   377 -----ELLNR----DNVGLVLLL-------QPLVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLA 425

  Fly   390 QTMMLSNELKTI--IDEASHSFRPGHKNDSNAVQLLLCGDFNSLPDSGVVEFLGKGRVSMDHL-- 450
            |..:|..|:..:  :.:.||            ..::||||.||:|||.:..|:..|.:..:.:
  Rat   426 QMAILLAEVDKVARLSDGSH------------CPIILCGDLNSVPDSPLYNFIRDGELQYNGMPA 478

  Fly   451 -------DF---------------KDMGYKSCLQRLLS--------------------------- 466
                   ||               ..:|...|.|.:.|
  Rat   479 WKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDFLLRFRFCDLACQ 543

  Fly   467 -----------NDT----------------------------NEFTHSFKLASAYNEDIMPH--- 489
                       .||                            ....|...|.|.|...:..|
  Rat   544 RPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIGTIQHCLHLTSVYTHFLPQHGRP 608

  Fly   490 --TNYTFDFKGIIDYIFYT---------------KTGMVPLGLLGPVSNDWLRENKVV----GCP 533
              |.........:||||::               :.|  .|.|||.:|   |...:::    |.|
  Rat   609 EVTTMPLGLGMTVDYIFFSAESCENENRSDHRLDRDG--TLKLLGRLS---LLSEEILWAANGLP 668

  Fly   534 HPHIPSDHFPLLVELELMHTA 554
            :|...|||..||....:..||
  Rat   669 NPFYSSDHLCLLASFGMEVTA 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twin	NP_732964.1	LRR	<52..>155	CDD:443914	15/63 (24%)
		leucine-rich repeat	76..98	CDD:275378	1/1 (100%)
		leucine-rich repeat	99..121	CDD:275378	8/21 (38%)
		leucine-rich repeat	122..144	CDD:275378	4/26 (15%)
		leucine-rich repeat	145..156	CDD:275378	2/10 (20%)
		Deadenylase_CCR4	209..550	CDD:197331	100/461 (22%)
Angel1	XP_017449718.1	EEP	268..683	CDD:469791	100/458 (22%)