Protein Alignment: CHORD and CHORDC1

• Sequence 1: NP_651226.1
• Gene: CHORD
• FlyBaseID: FBgn0029503
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_036256.2
• Gene: CHORDC1
• HGNCID: 14525
• Length: 332
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 145/339 (43%)
• Similarity: 218/339 (64%)
• Gaps: 26/339 (8%)

  Fly     4 CYNRGCGQLFDPQTNNDESCRHHPGEPFFHDAYKGWSCCNKKSVDFTEFLNIKGCTLAKHSNVKP 68
            ||||||||.|||:||:|::|.:|||.|.||||.||||||.:::.||::||:|.|||..:|::.||
Human     5 CYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCTKGRHNSEKP 69

  Fly    69 PEPEKPVKDESDKDEVIEVRAPIR----------EALPRPPIDSPLTVIQPTVAPALKDMVFAVK 123
            |||.||....::|.|:.|::...:          ||:.||..|.|:|.::..::.:||..:..:|
Human    70 PEPVKPEVKTTEKKELCELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLELKISASLKQALDKLK 134

  Fly   124 TPAA------QKSSDAIEVGTTCKNNGCTYSFTGNSSDFGECTYHPGVPIFHEGMKFWSCCQKRT 182
            ..:.      ::.:|.|::||:|||.||:.::.|..|....|.||.||||||||||:||||:::|
Human   135 LSSGNEENKKEEDNDEIKIGTSCKNGGCSKTYQGLESLEEVCVYHSGVPIFHEGMKYWSCCRRKT 199

  Fly   183 SDFSQFMAQKGCTYGEHKWVKENDDKKVVQCRYDWHQTATNVVMAIYAKKYDYSQSVIELNPIRL 247
            |||:.|:||:|||.|:|.|.|::..||||.||:|||||...|.:::|||......|.:|.|...|
Human   200 SDFNTFLAQEGCTKGKHMWTKKDAGKKVVPCRHDWHQTGGEVTISVYAKNSLPELSRVEANSTLL 264

  Fly   248 HVNLVFPEQDNARFDLDLELRGIVNVSNASAHMYGTKVEIKLPKLEPGSWSNLNFPNKKLPVVKK 312
            :|::||  :....||.:::|.|:::|..:...|..||:||.:.|.||..|::|     :||..||
Human   265 NVHIVF--EGEKEFDQNVKLWGVIDVKRSYVTMTATKIEITMRKAEPMQWASL-----ELPAAKK 322

  Fly   313 SQVEEKKKQEESD 325
               :||:|...:|
Human   323 ---QEKQKDATTD 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHORD	NP_651226.1	CHORD	3..63	CDD:282781	37/59 (63%)
		CHORD	138..199	CDD:282781	36/61 (59%)
		p23_melusin_like	213..301	CDD:107238	33/88 (38%)
CHORDC1	NP_036256.2	Interaction with PPP5C. {ECO:0000250}	2..77		45/72 (63%)
		CHORD	3..64	CDD:309895	37/59 (63%)
		Interaction with HSP90AA1 and HSP90AB1. {ECO:0000250}	65..316		99/258 (38%)
		CHORD	155..216	CDD:309895	36/61 (59%)
		p23_melusin_like	230..316	CDD:107238	33/93 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG1667
Hieranoid	1	1.000
Homologene	1	1.000				H8111
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2593
Isobase	1	0.950		0	Normalized mean entropy	S3736
OMA	1	1.010
OrthoDB	1	1.010				D1163528at2759
OrthoFinder	1	1.000				FOG0002103
OrthoInspector	1	1.000				T609652
orthoMCL	1	0.900				OOG5_129434
Panther	1	1.100			LDO	PTHR12621
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3238
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.820