Protein Alignment: CHORD and ITGB1BP2

• Sequence 1: NP_651226.1
• Gene: CHORD
• FlyBaseID: FBgn0029503
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_036410.1
• Gene: ITGB1BP2
• HGNCID: 6154
• Length: 347
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 143/341 (42%)
• Similarity: 194/341 (57%)
• Gaps: 23/341 (7%)

  Fly     4 CYNRGCGQLFDPQTNNDESCRHHPGEPFFHDAYKGWSCCNKKSVDFTEFLNIKGCTLAKHSNVKP 68
            |.|:||||.|||.||..:||.||||.|.||||.||||||.|::|||:|||||||||:..|...|.
Human     5 CRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTMGPHCAEKL 69

  Fly    69 PE---PEKPVKDES-DKDEVIEVRAPIREAL--PRPPIDSPLTVIQPTVAPALKDMVFAVK---- 123
            ||   ||.|....| .:.:.:.|.....|.|  .||..:.||.::...::.|| :|....|
Human    70 PEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQAL-EMALEQKELDQ 133

  Fly   124 TPAAQKSSDAIEVGTTCKNNGCTYSFTGNSSDFGECTYHPGVPIFHEGMKFWSCCQKRTSDFSQF 188
            .|.|...| .|..|::|:|.||...:.|..||...||||||.|.||||||.||||..:|.||..|
Human   134 EPGAGLDS-LIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAF 197

  Fly   189 MAQKGCTYGEHKWVKENDDKKVVQCRYDWHQTATNVVMAIYAKKYDYSQSVIELNPIRLHVNLVF 253
            :||.||..|.|.|.|:    ....||:|||||.:.||:.:|.:....:.:.::.:...|||::||
Human   198 LAQPGCRVGRHDWGKQ----LPASCRHDWHQTDSLVVVTVYGQIPLPAFNWVKASQTELHVHIVF 258

  Fly   254 PEQDNARFDLDLELRGIVNVSNASAHMYGTKVEIKLPKLEPGSWSNLNFPNKKLPVVKKSQ--VE 316
              ..|..|...::|.|::||..:|..:..::|||.|.|.:||||:.|..|:   .:.||::  |.
Human   259 --DGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSWAQLEHPD---ALAKKARAGVV 318

  Fly   317 EKKKQEESDEEFFDL 331
            .:..:||||:...||
Human   319 LEMDEEESDDSDDDL 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHORD	NP_651226.1	CHORD	3..63	CDD:282781	41/59 (69%)
		CHORD	138..199	CDD:282781	33/61 (54%)
		p23_melusin_like	213..301	CDD:107238	32/88 (36%)
ITGB1BP2	NP_036410.1	CHORD	3..64	CDD:282781	41/59 (69%)
		SH3-binding. {ECO:0000255}	28..31		2/3 (67%)
		SH3-binding. {ECO:0000255}	70..78		4/8 (50%)
		CHORD	148..208	CDD:282781	33/60 (55%)
		SH2-binding. {ECO:0000255}	158..161		1/3 (33%)
		SH3-binding. {ECO:0000255}	172..175		2/3 (67%)
		p23_melusin_like	218..304	CDD:107238	32/88 (36%)
		SH2-binding. {ECO:0000255}	234..237		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C179617156
eggNOG	1	0.900				E1_KOG1667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1163528at2759
OrthoFinder	1	1.000				FOG0002103
OrthoInspector	1	1.000				T609652
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR12621
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	8	7.810