DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and CG5568

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_647992.1	Gene:	CG5568 / 38658	FlyBaseID:	FBgn0035641	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	144/539 - (26%)
Similarity:	240/539 - (44%)	Gaps:	58/539 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SLGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLGVKQNDVVGLSSENSVNF 90
            |:|:.|..:.:.....|..:......|.:...:..:.:::|..::|||::|.|.||:....:.:.
  Fly    38 SIGEIIFQQMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHL 102

  Fly    91 ALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALS 155
            ....:|....|.....|:..|....::....::||::||......::| :.|:|...|: |:.:.
  Fly   103 TALAYACFFNGTPYHALHTEYEQSAIERLFGITKPRLIFCDGDEFEKV-QAATKGLQVQ-IVTMR 165

  Fly   156 GTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKD--EDVSLIVCSSGTTGLPKGVQLTQMNLL- 217
            ........|.|:.....:..|:       |...||  :.:..|:.||||:||||.|.::..:.:
  Fly   166 NHPAGILRIQDILTTPVEMNFR-------PVRLKDGTDQLLAILSSSGTSGLPKAVTISNSHQII 223

  Fly   218 ---ATLDS---QIQPTVIPMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAI 276
               ..:||   |..|..:.......:|:..   |...||.|...|         .|:.......|
  Fly   224 GSFLPVDSSIIQYNPNTLDWASGITMTINA---AVFSLTSIIEDC---------DFDPANLCGLI 276

  Fly   277 EKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGL 341
            ||||:.|.|:....:..|:..|.....||||:.....|.:..|.|.:::|:.|:....:...|.|
  Fly   277 EKYRISMVFVSSSQLAMLSNCPEFYAADLSSVKYFFYGGSNCSLEVQNKIRSRLSNECVNFSYTL 341

  Fly   342 SESTLSVLVQNDEFC-------KPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKG 399
            :|       .|...|       ||.|||....||..|::: :.|:..|.|..||:||.......|
  Fly   342 TE-------LNSPGCLNFNFDEKPNSVGRPVRGIQIKIVN-ELGEAQGPNVVGEICFNNGQKWPG 398

  Fly   400 YI---GDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDK 461
            |.   .:||..|.:  :.|.||||:||.|:|...||:||:|:::||:.....|:|||:::.....
  Fly   399 YYKNPEETKKMQDS--ENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYPSEIESVIAEMPN 461

  Fly   462 IKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASPA--KRLRGGVIFVDEIPKNP 524
            :.:|.|.|..|...|:...|.|||:...||...:|:::|.... ||  |:|.||.:.||.|.::.
  Fly   462 VVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKRI-PAKFKQLNGGALIVDHIIQSG 525

  Fly   525 SGKILR-----RILREMLK 538
            :.|..|     ..||.|.|
  Fly   526 NRKANRAATKAEFLRIMEK 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	142/536 (26%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	135/506 (27%)
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	140/533 (26%)
CG5568	NP_647992.1	Firefly_Luc_like	55..530	CDD:213279	135/506 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920