Protein Alignment CG6178 and SLC27A2

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_003636.2
• Gene: SLC27A2 / 11001
• HGNCID: 10996
• Length: 620
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 100/476 - (21%)
• Similarity: 183/476 - (38%)
• Gaps: 71/476 - (14%)

  Fly    72 LGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFAS---KI 133
            ||::|.|.|.|...|...:.......:.:|..:|.||.....:.:.|.......|::..|   :.
Human    99 LGLRQGDCVALLMGNEPAYVWLWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQA 163

  Fly   134 TIDRVAKVASKNK----FVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVS 194
            .::.:.....|:.    :|.......|.......:.::......|.::::..|::||
Human   164 AVEEILPSLKKDDVSIYYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPA-------- 220

  Fly   195 LIVCSSGTTGLPKGVQLTQMNLL----ATLDSQIQPTVIPMEEVTLLTVIPWFHA-------FGC 248
            |.:.:||||||||...:|...:.    .|..|.::     .::|..:| :|::|:       .||
Human   221 LYIYTSGTTGLPKAAMITHQRIWYGTGLTFVSGLK-----ADDVIYIT-LPFYHSAALLIGIHGC 279

  Fly   249 LTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLC 313
            :.      .||.|....||....|.....||.|.:...:..|:.:|...|  .|.:.....|.|.
Human   280 IV------AGATLALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSP--QKPNDRDHKVRLA 336

  Fly   314 GAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVG----VLKVGIYAKVID 374
            ....|..:...|..:|.|...|.:.|..:|..:..:   :...|.|:||    :.|..|...:|.
Human   337 LGNGLRGDVWRQFVKRFGDICIYEFYAATEGNIGFM---NYARKVGAVGRVNYLQKKIITYDLIK 398

  Fly   375 PDTGKLLGANERGELCF---KGD-GIM----------KGYIG-----DTKSTQTAIKDG--WLHT 418
            .|..|.....:....|.   ||: |::          .||.|     :.|..:...|.|  :.::
Human   399 YDVEKDEPVRDENGYCVRVPKGEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNS 463

  Fly   419 GDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIG--KPDEEAGELPLA 481
            ||:...|.:...:..||:.:..::||..|...|:...:...|.:::..|.|  .||.| |.:.:|
Human   464 GDLLMVDHENFIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE-GRIGMA 527

  Fly   482 FVVKQANVQLTENEVIQFVND 502
            .:..:.|.:....::.|.:.|
Human   528 SIKMKENHEFDGKKLFQHIAD 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	100/476 (21%)
SLC27A2	NP_003636.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	100/476 (21%)