Protein Alignment Hsp68 and Hspa14

DIOPT Version :10

• Sequence 1: NP_524474.1
• Gene: Hsp68 / 42852
• FlyBaseID: FBgn0001230
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 508
• Identity: 179/508 - (35%)
• Similarity: 291/508 - (57%)
• Gaps: 8/508 - (1%)

  Fly     1 MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVF 65
            |.|||:.||.|.:||.|::.|:.:::|||.|:|.||:.||:::.|:::|.|||.....:..::|.
Mouse     1 MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSEREQVVGLAAKQSRIRHVSSTVV 65

  Fly    66 DAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEA 130
            ..|:::||...|.:.|:.|......||..|||.:..::.....|..:||:::.::.:||||||.:
Mouse    66 KVKQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHS 130

  Fly   131 YLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDK-NLKGERNVLI 194
            .||:...|.|:|||..|.:.|:.|..:|...||.||||:|:||:||.||||:.: :..|:.|||:
Mouse   131 VLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLV 195

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALR 259
            |.|||.:..:|::.::.| ::.|.||....::||..|.:.|..:.|.||:|.:|.|:|.|.||:.
Mouse   196 FKLGGTSLSLSVMEVNSG-MYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMM 259

  Fly   260 RLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKM 324
            :|..:||.||.:||:...|:..:|:||||.||...|||||||.||..||....|.:.:.|:....
Mouse   260 KLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGF 324

  Fly   325 DKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDV 389
            ....|:.:||.|||:||||:|.|:::.|....|..||.|||.:..||||:|.||.|.:|:...|.
Mouse   325 TADDINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDS 389

  Fly   390 LLVDVAP---LSLGIETAGG-VMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGE-RALTK 449
            ::::.:.   |..|::.:|. ..|.|....:.:|.::..|... .....:|.::::|.| :...|
Mouse   390 VMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQA-PGRVSSVCLELYESEGKNSAK 453

  Fly   450 DNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIK 502
            :........|..:.....|:..|.....:..:|.|.||..:|.||..:.||::
Mouse   454 EEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp68	NP_524474.1	PTZ00009	2..635	CDD:240227	178/507 (35%)
Hspa14	NP_056580.2	ASKHA_NBD_HSP70_HSPA14	2..378	CDD:466836	150/376 (40%)