Protein Alignment Atg6 and Becn2

DIOPT Version :10

• Sequence 1: NP_651209.1
• Gene: Atg6 / 42850
• FlyBaseID: FBgn0264325
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001385797.1
• Gene: Becn2 / 289269
• RGDID: 1563293
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 151/434 - (34%)
• Similarity: 228/434 - (52%)
• Gaps: 43/434 - (9%)

  Fly    11 FACQRCLQPIVLDEQ----LEKISVHAMAELSLPIYG------------DNGNTLDPQDASSFDH 59
            |.|.||.:|:.|.:|    || :..||.....:|:.|            |.|.|.......:
  Rat     6 FLCHRCNEPLKLLQQQGGPLE-VQHHANLPTEMPVSGQSRVRTSHRAHSDGGRTCQGGACCT--- 66

  Fly    60 FVPPYRLTDSINGTGFMLVSDGRDNKKMSAAFKLKAELFDCLSSNSEIDHPLCEECADSMLEIMD 124
                           |.|:.:....:.:........|:|:.||....:|||||.:|.|::|..:|
  Rat    67 ---------------FTLLGESVSVRTLHTVQNTTIEIFEILSEQKVVDHPLCVDCTDNLLVQLD 116

  Fly   125 RELRIAEDEWDVYKAYLDE----LEQQRVAPNVEALDKELDELKRSEQQLLSELKELKKEEQSLN 185
            .:|.:...:...|:.:|:.    .|::..|.:.| |..||..|::.|.:|:.||::|......:.
  Rat   117 DQLTLVASDNQSYQGFLERQSLVSEEETEALHAE-LRAELSGLEQEEARLVQELEDLDGHHARVA 180

  Fly   186 DAIAEEEQEREELHEQEESYWREYTKHRRELMLTEDDKRSLECQIAYSKQQLDKLRDTNIFNITF 250
            ..:...:.|.:||::|.|.:...|:..:.|.:...|...|:|.|:.|:..||..||.|:||:.||
  Rat   181 AELRAAQAESKELYQQNEEHRASYSVLKMEQLELTDQLSSVENQLQYALGQLCHLRKTSIFDATF 245

  Fly   251 HIWHAGHFGTINNFRLGRLPSVSVDWSEINAAWGQTVLLLSALARKIGLTFERYRVVPFGNHSYV 315
            .|...|..|.|||||||.||:|.|.|:|||||||||.|||.:|::..||.|:||::||.|:|||:
  Rat   246 TISDDGPLGMINNFRLGCLPAVRVGWTEINAAWGQTALLLFSLSKMAGLQFQRYQLVPLGDHSYL 310

  Fly   316 EVLGENRELPLYGSGGFKFFWDTKFDAAMVAFLDCLTQFQKEVEKRDTEFLLPYKME--KGKIID 378
            :.|..:..|||:..|....|.:..||.||.||||||.||.:|.||.:....|||::.  :|.:.|
  Rat   311 KSLTADEVLPLFSDGNHSVFLNNTFDCAMKAFLDCLQQFVEETEKDERYPCLPYRIHPLEGVMED 375

  Fly   379 -PSTGNSYSIKIQFNSEEQWTKALKFMLTNLKWGLAWVSSQFVS 421
             ..:|:...|:...|:||:|::||||||.:||..:||.||...|
  Rat   376 IGDSGDCCPIRTHLNTEEEWSRALKFMLADLKLIVAWASSSSTS 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg6	NP_651209.1	APG6_N	110..237	CDD:465452	34/130 (26%)
		APG6	243..417	CDD:461178	86/176 (49%)
Becn2	NP_001385797.1	APG6_N	102..232	CDD:465452	34/130 (26%)
		APG6	238..415	CDD:461178	86/176 (49%)