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Protein Alignment Mettl3 and mettl14

DIOPT Version :10

Sequence 1:	NP_651204.1	Gene:	Mettl3 / 42844	FlyBaseID:	FBgn0039139	Length:	608	Species:	Drosophila melanogaster
Sequence 2:	NP_996954.1	Gene:	mettl14 / 404603	ZFINID:	ZDB-GENE-040426-2328	Length:	455	Species:	Danio rerio

Alignment Length:	385	Identity:	102/385 - (26%)
Similarity:	156/385 - (40%)	Gaps:	92/385 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 LKAQQATAE------MAAKKKQERRDEKELRPDVDAGENVT--GKVPKTESAAED-GEIIAEVIN 293
            |.|||..||      .....|.|:::.:|.|....|..:::  |...|..:..|| .|.:.|...
Zfish    18 LLAQQLGAESPDSIGAVLNSKDEQKEIEETRETCRASFDISVPGAKRKCLNEGEDPEEDVEEQKE 82

  Fly   294 NCEAESQESTDGSDTCSSETTDKCTKLHFKKIIQAHTDESLGDCSFLNTCFHMATCKYVHYEVDT 358
            :.|.:.||.   |........|..|.|...:.:..|.|                   |..:.|||
Zfish    83 DVEPQHQEE---SGPYEEVYKDSSTFLKGTQSLNPHND-------------------YCQHFVDT 125

  Fly   359 LPHINTN---------KPTDVKTKLSLKRSVDS--SCTLYPPQWIQCDLRFLDMTVLG-KFAVVM 411
             .|...|         :..:...:..|.|..|.  |.|..||.::|.|....|:..|. ||.|::
Zfish   126 -GHRPQNFIRDGGLADRFEEYPKQRELIRLKDELISATNTPPMYLQADPDTFDLRELKCKFDVIL 189

  Fly   412 ADPP------------------WDIHMELPYGTMSDDEMRALGVPALQDDGLIFLWV-TGRAMEL 457
            .:||                  ||..|:|     :.:|:.::       ...:|||. :|..::|
Zfish   190 IEPPLEEYYRESGIIANERFWNWDDIMKL-----NIEEISSI-------RSFVFLWCGSGEGLDL 242

  Fly   458 GRDCLKLWGYERVDELIWVKTNQLQRIIRTGRTGHW-----LNHGKEHCLVGMKGNPTN------ 511
            ||.||:.||:.|.:::.|:|||:    ...|:|...     ....|||||:|:||....
Zfish   243 GRMCLRKWGFRRCEDICWIKTNK----NNPGKTKTLDPKAVFQRTKEHCLMGIKGTVRRSTDGDF 303

  Fly   512 LNRGLDCDVIVAE--VRATSHKPDEIYGIIERLSPGTRKIELFGRPHNIQPNWITLGNQL 569
            ::..:|.|:|:.|  ......||.||:.|||....|.|::.||||...|:|.|:|:|..|
Zfish   304 IHANVDIDLIITEEPEMGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTL 363

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.