DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Pli and Peli1

Sequence 1:NP_001097890.1 Gene:Pli FlyBaseID:FBgn0025574 Length:424 Species:Drosophila melanogaster
Sequence 2:NP_075813.2 Gene:Peli1 MGIID:1914495 Length:418 Species:Mus musculus

Alignment Length:409 Identity:247/410 (60%)
Similarity:309/410 (75%) Gaps:9/410 (2%)


  Fly    23 KPRLRYGELVILGYNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHYIVQSPQTSKAILDANQHS 87
            |..::||||::|||||.||.||||||:|:|.|.||.:|:|||.|..:|..:||.:|||.:.:|||
Mouse    12 KAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHS 76

  Fly    88 ISYTLSRNQAVIVEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDK--KDAKVMQSTISRFACRI 150
            |||||||.|.|:|||..|:.|||||:|||:||||||||.||:||.:  .|.:.:|||||||||||
Mouse    77 ISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRI 141

  Fly   151 LVNRCEPAKARIFAAGFDSSRNIFLGEKATKWQ-DNVEIDGLTTNGVLIMHPKGSFCGGNAKCGL 214
            :..|..|..|||:|||||||:||||||||.||: .:.::|||||||||:|||:..|. .::|.|:
Mouse   142 ICERSPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFT-EDSKPGI 205

  Fly   215 WRECSVGGDVFSLRESRSAQQKGQPIYDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEK 279
            |||.||.|:||||||:|||||:|:.:..|.|.||||:||||||||||||:||||.|:||...||.
Mouse   206 WREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEA 270

  Fly   280 LIDAINAGRPQCPVGLNTLVIP--RKVNIGDQVNQPYVYLNCGHVQGHHDWG-QDENTGA-RRCP 340
            |...|||.|||||||.|||..|  ::.::.|: .||:||||||||.|:|:|| ::|..|. |.||
Mouse   271 LRQEINAARPQCPVGFNTLAFPSMKRKDVVDE-KQPWVYLNCGHVHGYHNWGNKEERDGKDRECP 334

  Fly   341 MCLELGPVVTLCMGLEPAFYVDVGAPTYAFNPCGHMATEKTVKYWANVEIPHGTNGFQAVCPFCA 405
            ||..:||.|.|.:|.|..||||.|.||:||:||||:.:|||..||:.:.:||||:.|.|.|||||
Mouse   335 MCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCA 399

  Fly   406 TPLDGATGYIKLIFQDNLD 424
            ..|.|..|||:||||..||
Mouse   400 HQLAGEQGYIRLIFQGPLD 418

Known Domains:


GeneSequenceDomainRegion External IDIdentity
PliNP_001097890.1 Pellino 21..424 CDD:282553 246/408 (60%)
Peli1NP_075813.2 Pellino 10..418 CDD:282553 246/408 (60%)
Ring-like domain, necessary for ubiquitination of RIPK3. {ECO:0000250|UniProtKB:Q96FA3} 311..399 49/88 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C26113490
eggNOG 1 0.900 E1_KOG3842
Hieranoid 1 1.000
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 498 1.000 Inparanoid score I1356
Isobase 1 0.950 0 Normalized mean entropy S2993
OMA 1 1.010
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 FOG0000914
OrthoInspector 1 1.000 T615536
orthoMCL 1 0.900 OOG5_129859
Panther 1 1.100 O PTHR12098
Phylome 1 0.910 0.857 Consistency score
RoundUp 1 1.030 avgDist Average_Evolutionary_Distance R4716
TreeFam 1 0.960
1312.740

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