Protein Alignment: Pli and Peli1

• Sequence 1: NP_001097890.1
• Gene: Pli
• FlyBaseID: FBgn0025574
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_075813.2
• Gene: Peli1
• MGIID: 1914495
• Length: 418
• Species: Mus musculus
• Alignment Length: 409
• Identity: 247/410 (60%)
• Similarity: 309/410 (75%)
• Gaps: 9/410 (2%)

  Fly    23 KPRLRYGELVILGYNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHYIVQSPQTSKAILDANQHS 87
            |..::||||::|||||.||.||||||:|:|.|.||.:|:|||.|..:|..:||.:|||.:.:|||
Mouse    12 KAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHS 76

  Fly    88 ISYTLSRNQAVIVEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDK--KDAKVMQSTISRFACRI 150
            |||||||.|.|:|||..|:.|||||:|||:||||||||.||:||.:  .|.:.:|||||||||||
Mouse    77 ISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRI 141

  Fly   151 LVNRCEPAKARIFAAGFDSSRNIFLGEKATKWQ-DNVEIDGLTTNGVLIMHPKGSFCGGNAKCGL 214
            :..|..|..|||:|||||||:||||||||.||: .:.::|||||||||:|||:..|. .::|.|:
Mouse   142 ICERSPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFT-EDSKPGI 205

  Fly   215 WRECSVGGDVFSLRESRSAQQKGQPIYDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEK 279
            |||.||.|:||||||:|||||:|:.:..|.|.||||:||||||||||||:||||.|:||...||.
Mouse   206 WREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEA 270

  Fly   280 LIDAINAGRPQCPVGLNTLVIP--RKVNIGDQVNQPYVYLNCGHVQGHHDWG-QDENTGA-RRCP 340
            |...|||.|||||||.|||..|  ::.::.|: .||:||||||||.|:|:|| ::|..|. |.||
Mouse   271 LRQEINAARPQCPVGFNTLAFPSMKRKDVVDE-KQPWVYLNCGHVHGYHNWGNKEERDGKDRECP 334

  Fly   341 MCLELGPVVTLCMGLEPAFYVDVGAPTYAFNPCGHMATEKTVKYWANVEIPHGTNGFQAVCPFCA 405
            ||..:||.|.|.:|.|..||||.|.||:||:||||:.:|||..||:.:.:||||:.|.|.|||||
Mouse   335 MCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCA 399

  Fly   406 TPLDGATGYIKLIFQDNLD 424
            ..|.|..|||:||||..||
Mouse   400 HQLAGEQGYIRLIFQGPLD 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pli	NP_001097890.1	Pellino	21..424	CDD:282553	246/408 (60%)
Peli1	NP_075813.2	Pellino	10..418	CDD:282553	246/408 (60%)
		Ring-like domain, necessary for ubiquitination of RIPK3. {ECO:0000250|UniProtKB:Q96FA3}	311..399		49/88 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C26113490
eggNOG	1	0.900				E1_KOG3842
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	498	1.000	Inparanoid score	I1356
Isobase	1	0.950		0	Normalized mean entropy	S2993
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000914
OrthoInspector	1	1.000				T615536
orthoMCL	1	0.900				OOG5_129859
Panther	1	1.100			O	PTHR12098
Phylome	1	0.910		0.857	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4716
TreeFam	1	0.960
	13	12.740