Protein Alignment: Pli and PELI3

• Sequence 1: NP_001097890.1
• Gene: Pli
• FlyBaseID: FBgn0025574
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_659502.2
• Gene: PELI3
• HGNCID: 30010
• Length: 469
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 223/449 (50%)
• Similarity: 292/449 (65%)
• Gaps: 36/449 (8%)

  Fly    10 SPILAEDGGDGH--DKPRLRYGELVILG------------------------YNGYLPQGDRGRR 48
            |.:|:..|.|..  ::| ::||||::||                        |||.|..||:|||
Human    25 SCVLSSPGEDAQPGEEP-IKYGELIVLGCCEEGGEETEAQRGEVTGPRAHSCYNGCLASGDKGRR 88

  Fly    49 RSKFVLHKRTEASGVKRSKHYIVQSPQTSKAILDANQHSISYTLSRNQAVIVEYKEDTETDMFQV 113
            ||:..|.:|:.|:|||....:.:.:|..|||:.:..||||||||||:.:|||||..|::|||||:
Human    89 RSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQI 153

  Fly   114 GRSSESPIDFVVMDTLP-GDKKDAKVMQSTISRFACRILVNRCEPAKARIFAAGFDSSRNIFLGE 177
            |||:|:.|||||.||.| |...:....||||||:|||||.:|..|..|||:|||||:|.||||||
Human   154 GRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGE 218

  Fly   178 KATKWQ--DNVEIDGLTTNGVLIMHPKGSFCGGNAKCGLWRECSVGGDVFSLRESRSAQQKGQPI 240
            :|.||:  |.: :|||||||||:|||.|.|...:|. |:|||.||.|:|::||:||||||:|:.:
Human   219 RAAKWRTPDGL-MDGLTTNGVLVMHPAGGFSEDSAP-GVWREISVCGNVYTLRDSRSAQQRGKLV 281

  Fly   241 YDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEKLIDAINAGRPQCPVGLNTLVI--PRK 303
            .:|.|:||||:||||||||||||:..||..:||...||......||.||||||||:||..  |.:
Human   282 ENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPAR 346

  Fly   304 VNIGDQVNQPYVYLNCGHVQGHHDWG--QDENTGARRCPMCLELGPVVTLCMGLEPAFYVDVGAP 366
            ........||:||:.||||.|:|.||  ::.....|.||:|..:||.|.|.:|.|....:|.|.|
Human   347 GRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPP 411

  Fly   367 TYAFNPCGHMATEKTVKYWANVEIPHGTNGFQAVCPFCATPLDGATGYIKLIFQDNLD 424
            ::||.||||:.:|||.:|||...:||||:.|.|.||||...|.|..|.::||||..||
Human   412 SHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pli	NP_001097890.1	Pellino	21..424	CDD:282553	218/436 (50%)
PELI3	NP_659502.2	Pellino	37..469	CDD:309722	218/435 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C26115281
eggNOG	1	0.900				E1_KOG3842
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	502	1.000	Inparanoid score	I1341
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D251367at33208
OrthoFinder	1	1.000				FOG0000914
OrthoInspector	1	1.000				T608706
orthoMCL	1	0.900				OOG5_129859
Panther	1	1.100			O	PTHR12098
Phylome	1	0.910		0.857	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R4716
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	13	12.800