DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17111 and cutl-17

DIOPT Version :9

Sequence 1:	NP_651119.2	Gene:	CG17111 / 42727	FlyBaseID:	FBgn0039048	Length:	792	Species:	Drosophila melanogaster
Sequence 2:	NP_001379101.1	Gene:	cutl-17 / 185474	WormBaseID:	WBGene00009541	Length:	912	Species:	Caenorhabditis elegans

Alignment Length:	920	Identity:	158/920 - (17%)
Similarity:	297/920 - (32%)	Gaps:	308/920 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 IVGFRPPLEYLNADNRIYGPEMVSNFKTRNGQ---------QELPVSQVCWRICNEDPDCIAYVH 102
            ::||..|:  |.|.:|...|...:..::...:         :::.::: |...|:..
Worm     6 LLGFLVPI--LQASSRCSAPNATTYLRSEGTRLMEFSTKVMKDVTLNE-CANACSNS-------- 59

  Fly   103 LLDTDECHGYSYFERTSRYLAIS---------GELPLVADGEAV-FYEKTCLRVPDACRGRLWAL 157
             |.|:||..:.|   .:..|..|         |...|....:.: |:::.||.....|:.. ::.
Worm    60 -LSTEECLSFEY---DASILQCSHHSDDGQPFGASVLAKASQTISFFQQICLLEEAVCKAP-YSF 119

  Fly   158 TKIPGSTLVYHSKKTISTLVTRRECAERCFFETQ---FRCLSASFAPSYRNNRERFRGEAGPGQR 219
            .:.|.|.|:.|:.|.: |:....:|..:|....:   |.|.||.:   |...
Worm   120 ERYPQSILIGHAMKVL-TVDGLSDCLSKCALSQRSYDFLCKSAIY---YYET------------- 167

  Fly   220 PSPRLGRCMLSDRDKTVQPDAFRAAPYDE--EYMENQCHERAIESDNCSY------ELYANSSFI 276
                 |.|:::..:|.:.|..|:....|.  :|.||.|.:.:.:.:...:      .|...|..:
Worm   168 -----GECIMNRDNKFIYPKLFKTNILDTLVDYFENNCADVSCKPEETLHWVRTEEYLIDESKDV 227

  Fly   277 YAEARYLGLSQKECQAMCSH----EAKFYCQGVSFYYVNQLSLSECLLHSED--IVSLGPRSLKL 335
            ..|:.    ..:||..:|.:    |..|.|:  :|.|.|  |..||.|.:|.  :...|.:...|
Worm   228 IVESS----DAQECNQLCQNNKIGEENFPCK--AFAYSN--SKQECHLTAESSYVGHKGDKRFNL 284

  Fly   336 R--ENSVYMRRVKCLDVRVFCTRDEMTIKYNPKDWFVGKIYASMHSKDCLARGSGNGSVLLTLQI 398
            .  .:..|..:. ||...:.|......:..|.......|..:::...:||::...:|:
Worm   285 APLNSGEYFEKY-CLPTNLQCIEASFELVANRMMTSAYKTISALSQHECLSQCMNDGA------- 341

  Fly   399 GSEVKENRCGILRAYEMTQEYQRTFISAL-----------------------------------V 428
                   ||.....:.|..|.|.:.||..                                   .
Worm   342 -------RCSSATYFYMDDECQLSDISQFSRPNEFVVANFTDYFDKICDPADPKPMLTTPETPPE 399

  Fly   429 VIQNN-------------------------PNVQTQGDRLIK----VGCIQS-NATTSLG----- 458
            :|||:                         .:|:.:.|.|:|    |..:.. ..||::|
Worm   400 LIQNSVDEEETTSERSIAQGAANFEVATTGTSVEFEDDNLLKDNQAVDAVHGVTTTTNIGEKRET 464

  Fly   459 -VSVRDSSV-----------DSSEPVPSAIALES-------------------SLEYTEHMFPHE 492
             |.:.::.:           ||.|..|...:.||                   ||::..   |..
Worm   465 KVEIEETVIDDADEFSREIDDSHEESPLTSSEESEGRVKARLSTECRMSGISVSLKFAT---PTS 526

  Fly   493 GVV----HYNSSTGPHPHPSIS-LQI-------------------LDLSHQHETNDVQ-----IG 528
            |.:    |::|......:.|.: |.|                   .|.:...|.||::     ..
Worm   527 GTIYIKDHFSSCRQSFSNTSFAELHIPFPTEDDSKCGGIESEPHKWDYNVVVERNDMKTPSLVTT 591

  Fly   529 QNLELQIVAEYSPQQLAEHMELQLAPLP-----DFRATSLVAKTADNENFV-------------L 575
            ::...|:..::|  ::|:  :.|||.|.     |.::..::.:...|...|             .
Worm   592 KDKTFQVSCDFS--KIAD--KNQLAALKPKVEGDVKSEKVLMEIVRNGQAVTTVPLGAEVSLRWT 652

  Fly   576 LIDE------------------------------RGCPTDASVFPALERVHTASRSMLRARFHAF 610
            :|||                              :|||.:......|......:..:...:...|
Worm   653 VIDETDKLGFFINECIAERVGGQPPYPEPLKIIYQGCPEEKVRNRLLHDPVVKNGEVYSTKMKVF 717

  Fly   611 KFSGTANVSFDVKIRFCVERCSPSNCIS------SSWQRRRRQAD-----QPDRRPEDLRVQNPV 664
            :|.|:..|.....|..|||:|.|..|..      .|:.|::|.::     :...:.|..:.:...
Worm   718 RFDGSRRVRIKCSIDVCVEKCPPVICDDLEIRNVDSFGRKKRNSNVEKWLKAGNKKETRKRRMVT 782

  Fly   665 YISTVVD-------VAPQPDNFTRSQEELPLNYNIRVHGPDQSNTNSYLYGERGVLLIAGIDDPL 722
            ...|:.|       |.|:|:..|.|.......|.:      |.:...:|.....:|::..|...|
Worm   783 GTLTITDEEETNTTVKPRPEFSTSSSSSSQQQYCV------QKDRIEFLIVIVVLLILLQIGLAL 841

  Fly   723 HLDNVCINQS 732
            .....|:::|
Worm   842 FFYRKCVSRS 851

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17111	NP_651119.2	PAN_1	159..255	CDD:278453	22/100 (22%)
CG17111	NP_651119.2	PAN_AP_HGF	270..344	CDD:238532	19/81 (23%)
cutl-17	NP_001379101.1	PAN_1	26..106	CDD:394981	12/92 (13%)
		PAN_AP_HGF	114..199	CDD:238532	21/107 (20%)
		PAN_AP	208..295	CDD:214680	20/94 (21%)
		PAN_AP_HGF	308..380	CDD:238532	12/85 (14%)
		Zona_pellucida	509..744	CDD:421542	40/241 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D200714at33208
OrthoFinder	1	1.000	-	-		FOG0005301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.980