Protein Alignment CG17121 and Rdh10

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_598593.1
• Gene: Rdh10 / 98711
• MGIID: 1924238
• Length: 341
• Species: Mus musculus
• Alignment Length: 308
• Identity: 93/308 - (30%)
• Similarity: 146/308 - (47%)
• Gaps: 40/308 - (12%)

  Fly    57 VIVFLLLLPLVLLAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKLAV 121
            |:.|.:|...||.|.        .:.:..|||.|:|:|.|:||.||||||...||.|||...|.:
Mouse     9 VVTFKVLWAFVLAAA--------RWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVL 65

  Fly   122 VDVNSKGCYETVELLSKIPRCVAKA------------------------YKNDVSSPRELQLMAA 162
            .|:|::...||..::..|.|.:..|                        |..||.....:.|.|.
Mouse    66 WDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAE 130

  Fly   163 KVEKELGPVDILVNNASLMPMTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAV 227
            :|.||:|.|.:|||||.::..........:.|:..:.:|..::..|||.|||.|:....||:|.|
Mouse   131 RVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTV 195

  Fly   228 NALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGI 292
            .:..||....|...|.|:|:|:.||.|||..||:.::.|.::||:...||:    |..:.....|
Mouse   196 ASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLV----DTGMFRGCRI 256

  Fly   293 AKS----YPGLPTPYVAEKIVKGVLLNERMVYVPKIFALSVWLLRLLP 336
            .|.    .|.|...|..::.::.:|.::.||..|::..:..::..:||
Mouse   257 RKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILP 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	82/271 (30%)
Rdh10	NP_598593.1	17beta-HSDXI-like_SDR_c	38..307	CDD:187598	82/271 (30%)