Protein Alignment CG17121 and dhrs3b

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001006070.1
• Gene: dhrs3b / 450050
• ZFINID: ZDB-GENE-041010-172
• Length: 302
• Species: Danio rerio
• Alignment Length: 299
• Identity: 97/299 - (32%)
• Similarity: 148/299 - (49%)
• Gaps: 38/299 - (12%)

  Fly    54 NLKVIVFLLLLPLVLLAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCK 118
            :||.:..::|||:.:|...:|..:.:.  |..:.:|::|.|.|:||||.|:||.:..|.|.||.|
Zfish     2 DLKALGCVVLLPIQILYYTVKATVCWF--LPSRRRDLTGDVVLITGGGRGIGRHLAKEFAVRGAK 64

  Fly   119 LAVVDVNSKGCY-ETVELLSKI-PRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNA--- 178
            ..::...::.|. ||.|.::.: ..|  ..:..||::..|:...|..|.:::|.|.||||||
Zfish    65 KLILWGRTEKCLKETCEEITLMGTEC--HYFVCDVANREEVYKQAKVVREKVGDVTILVNNAAVV 127

  Fly   179 ---SLMPMTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAG 240
               ||:.......|||..|:|:.|      ..|||.|||:|:..::||:|.||::..|.|:|||.
Zfish   128 HGKSLLDSDDDALLKSQHINTMGQ------FWTTKAFLPRMLELQNGHVVCVNSILSLSPIPGAI 186

  Fly   241 IYTATKYGIEGFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDA----GIAKSYPGLPT 301
            .|..::.....|||||  .|.|.||..|..|..          ||..::.    |:...:|.|..
Zfish   187 DYCTSEASSLAFMESL--TLGLLDCPGVACTTV----------LPFHTNTEMFQGMRVRFPQLFP 239

  Fly   302 P----YVAEKIVKGVLLNERMVYVPKIFALSVWLLRLLP 336
            |    .||::.|..|..|...||:|......|.|..:||
Zfish   240 PLKPEVVAQRTVDAVRTNTAFVYLPWTMNALVILKSMLP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	87/259 (34%)
dhrs3b	NP_001006070.1	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	78/246 (32%)