Protein Alignment CG17121 and Dhrs3

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_001032276.3
• Gene: Dhrs3 / 313689
• RGDID: 1305584
• Length: 302
• Species: Rattus norvegicus
• Alignment Length: 292
• Identity: 94/292 - (32%)
• Similarity: 147/292 - (50%)
• Gaps: 38/292 - (13%)

  Fly    61 LLLLPLVLLAVFLKHLLDYLFALGL----KEKDVSGKVALVTGGGSGLGREICLELARRGCKLAV 121
            |::|||.::.:..|      .|:||    |.:|:|.:..|:||||.|:||.:..|.|.||.:..|
  Rat     9 LVVLPLQMIYLVTK------AAVGLVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIV 67

  Fly   122 VDVNSKGCY-ETVELLSKI-PRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNA------ 178
            :...::.|. ||.|.:.:: ..|  ..:..||.:..|:..||..|.:::|.:.||||||
  Rat    68 LWGRTEKCLKETTEEIRQMGTEC--HYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGK 130

  Fly   179 SLMPMTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYT 243
            |||.......|||..::|     ||.: .|||.|||:|:..::||:|.:|::..|..:|||..|.
  Rat   131 SLMDSDDDALLKSQHVNT-----LGQF-WTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYC 189

  Fly   244 ATKYGIEGFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKSYPGLPTPY----V 304
            .:|.....|||||  .|.|.||..|..|....:  .||.::    ..|:...:|.|..|.    |
  Rat   190 TSKASAFAFMESL--TLGLLDCPGVSATTVLPF--HTSTEM----FQGMRVRFPNLFPPLKPETV 246

  Fly   305 AEKIVKGVLLNERMVYVPKIFALSVWLLRLLP 336
            |.:.|:.|..|:.::.:|....:.:.|..:||
  Rat   247 ARRTVEAVQQNQALLLLPWTMNILIILKSILP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	83/255 (33%)
Dhrs3	NP_001032276.3	17beta-HSDXI-like_SDR_c	53..281	CDD:187598	75/242 (31%)