Protein Alignment CG17121 and dhs-4

DIOPT Version :10

• Sequence 1: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Sequence 2: NP_492563.1
• Gene: dhs-4 / 172810
• WormBaseID: WBGene00000968
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 88/300 - (29%)
• Similarity: 157/300 - (52%)
• Gaps: 17/300 - (5%)

  Fly    55 LKVIVFLLLLPLVLLAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKL 119
            |::::.|..|.:..|...:|:.|.|..   |.:||:..|..|:||.|:|||:.:..:.|.||..|
 Worm     6 LEIVILLFNLLIQNLISLIKYALPYSL---LPKKDLYRKKVLITGAGNGLGKLLAQKFAARGATL 67

  Fly   120 AVVDVNSKGCYETVELLSKI--PRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNASLMP 182
            .:.|:|.:   ...||.::|  .:..|.:|:.::..|.::..:..:|..::|.||||||||.:..
 Worm    68 ILWDINLQ---SVDELKNEIRGNQGEAHSYEVNLCDPGKIAQVGQQVINDIGKVDILVNNAGIAT 129

  Fly   183 MTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKY 247
            .........:||:....:|:.::..|.::|||.|:...:||:|.:.:.||.:...|...|::||:
 Worm   130 AKMILDSSENEINRSFDVNVKAHFYTVQQFLPAMLKDNNGHIVTIASAAGKMGSSGLADYSSTKH 194

  Fly   248 GIEGFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKSYPG----LPTPYVAEKI 308
            ...||.:||.||:..|:.:.|:||:...|.:.||    :....|.|..:|.    |.|.||.:||
 Worm   195 AAVGFHDSLVAEIMESEKNGVKTTLVCPYYVHTS----MFDATGAATRFPWIFPILDTDYVVQKI 255

  Fly   309 VKGVLLNERMVYVPKIFALSVWLLRLLPTKWQDYMLLRFY 348
            .:.:...:..:..|:.|.|....:::||.|.| .|:.:|:
 Worm   256 FEAIETEQEFLVTPRAFYLVFAGIQILPYKAQ-AMVAQFF 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	73/249 (29%)
dhs-4	NP_492563.1	17beta-HSDXI-like_SDR_c	43..286	CDD:187598	73/249 (29%)