DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klg and ntm

DIOPT Version :9

Sequence 1:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	76/262 - (29%)
Similarity:	127/262 - (48%)	Gaps:	14/262 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 GDTLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLI----DGYNLEISDLEPQDAGDY 175
            ||:.:|.|.|:|....| .|...:.:|...|...:.|.||.|:    ..|::||.:::..|.|.|
Frog    51 GDSAILRCTVDNRVTRV-AWLNRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPY 114

  Fly   176 VC--QISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSGA 238
            .|  |..:.....:||.: :.|||  |.:..|..:...:|..::|.|..:|.|.|.:.|...|
Frog   115 TCSVQTDNHPKTSRVHLI-VQVPP--RIVDISSSIAVNEGSNVSLICIANGRPEPVVNWRYLS-- 174

  Fly   239 NKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGF 303
            .|:...:.:...|.:..:.|:|:|:|:|:|.|.|..|....::|.|.|||.| ::...|.:..|.
Frog   175 PKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYI-LDAQNIGAPLGH 238

  Fly   304 EAKLVCIVFADPVATVSWYQNSFPIQSTDRRI-MATRANRHMLTIRHIQQEDFGNYSCVADNSLG 367
            ...|.|...|.|.|...||:....:..:.|.: :..|.....:|..::.::|:|||:|:|.|.||
Frog   239 RGILQCEASAVPAADFFWYKEDKRLSDSWRGVKVENRETISRVTFLNVSEQDYGNYTCMAKNLLG 303

  Fly   368 RS 369
            .|
Frog   304 HS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klg	NP_524454.2	DUF1370	63..>124	CDD:284518	4/8 (50%)
		IG_like	109..195	CDD:214653	24/85 (28%)
		Ig	118..191	CDD:143165	22/78 (28%)
		IG_like	205..274	CDD:214653	19/68 (28%)
		IGc2	213..273	CDD:197706	17/59 (29%)
		IGc2	301..367	CDD:197706	18/66 (27%)
		FN3	392..486	CDD:238020
ntm	XP_004916061.1	Ig	45..133	CDD:299845	24/83 (29%)
		IG_like	45..133	CDD:214653	24/83 (29%)
		IG_like	143..220	CDD:214653	21/78 (27%)
		IGc2	150..209	CDD:197706	17/60 (28%)
		ig	227..311	CDD:278476	22/79 (28%)
		IG_like	230..311	CDD:214653	22/76 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000