DRSC/TRiP Functional Genomics Resources

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Protein Alignment klg and ntm

DIOPT Version :10

Sequence 1:NP_524454.2 Gene:klg / 42707 FlyBaseID:FBgn0017590 Length:545 Species:Drosophila melanogaster
Sequence 2:XP_004916061.1 Gene:ntm / 100492453 XenbaseID:XB-GENE-6045425 Length:374 Species:Xenopus tropicalis


Alignment Length:262 Identity:76/262 - (29%)
Similarity:127/262 - (48%) Gaps:14/262 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   115 GDTLVLPCQVENLGNFVLLWRRGTNVLTASNIMVTRDERVRLI----DGYNLEISDLEPQDAGDY 175
            ||:.:|.|.|:|....| .|...:.:|...|...:.|.||.|:    ..|::||.:::..|.|.|
 Frog    51 GDSAILRCTVDNRVTRV-AWLNRSTILYTGNDKWSIDPRVVLLANTKSQYSIEIQNVDIYDEGPY 114

  Fly   176 VC--QISDKINRDQVHTVEILVPPSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSGA 238
            .|  |..:.....:||.: :.|||  |.:..|..:...:|..::|.|..:|.|.|.:.|...|  
 Frog   115 TCSVQTDNHPKTSRVHLI-VQVPP--RIVDISSSIAVNEGSNVSLICIANGRPEPVVNWRYLS-- 174

  Fly   239 NKSTARIGDGPILTLEKLERQQAGVYQCTADNGVGDPVTVDMRLDVLYPPDIQVEKSWIHSGEGF 303
            .|:...:.:...|.:..:.|:|:|:|:|:|.|.|..|....::|.|.|||.| ::...|.:..|.
 Frog   175 PKARGFVSEDEYLEITGITREQSGIYECSASNDVSAPDVRRVKLTVNYPPYI-LDAQNIGAPLGH 238

  Fly   304 EAKLVCIVFADPVATVSWYQNSFPIQSTDRRI-MATRANRHMLTIRHIQQEDFGNYSCVADNSLG 367
            ...|.|...|.|.|...||:....:..:.|.: :..|.....:|..::.::|:|||:|:|.|.||
 Frog   239 RGILQCEASAVPAADFFWYKEDKRLSDSWRGVKVENRETISRVTFLNVSEQDYGNYTCMAKNLLG 303

  Fly   368 RS 369
            .|
 Frog   304 HS 305

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klgNP_524454.2 IG_like 109..195 CDD:214653 24/85 (28%)
Ig strand B 118..122 CDD:409353 1/3 (33%)
Ig strand C 131..135 CDD:409353 1/3 (33%)
Ig strand E 160..164 CDD:409353 1/3 (33%)
Ig strand F 174..179 CDD:409353 2/6 (33%)
Ig strand G 188..191 CDD:409353 2/2 (100%)
Ig_3 196..270 CDD:464046 20/73 (27%)
Ig_3 287..364 CDD:464046 21/77 (27%)
FN3 392..486 CDD:238020
ntmXP_004916061.1 Ig 45..133 CDD:472250 24/83 (29%)
Ig strand B 54..58 CDD:409353 1/3 (33%)
Ig strand C 66..70 CDD:409353 1/4 (25%)
Ig strand E 99..103 CDD:409353 1/3 (33%)
Ig strand F 113..118 CDD:409353 2/4 (50%)
Ig strand G 126..129 CDD:409353 0/2 (0%)
Ig_3 136..206 CDD:464046 20/73 (27%)
ig 227..311 CDD:395002 22/79 (28%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 0/3 (0%)
Ig strand F 293..298 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.

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