Protein Alignment: CG4813 and RNF220

• Sequence 1: NP_651088.1
• Gene: CG4813
• FlyBaseID: FBgn0039013
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: XP_005271049.1
• Gene: RNF220
• HGNCID: 25552
• Length: 592
• Species: Homo sapiens
• Alignment Length: 408
• Identity: 146/409 (36%)
• Similarity: 201/409 (49%)
• Gaps: 72/409 (18%)

  Fly    25 ICPTCDVKIKRSQVADHCQVEMERLHN-PIS-------AVTPPTPTS------------GATASE 69
            |||.|.|.::.|::.:|.:.|:|:|.. |.|       |:.|.||.|            ..|||.
Human   223 ICPICQVLLRPSELQEHMEQELEQLAQLPSSKNSLLKDAMAPGTPKSLLLSASIKREGESPTASP 287

  Fly    70 ESGSVSG--GRQPWSVFQRVQRNRQARQRQRTRKRPASPAPPATVNPTVAAAPPPAAATPSVAAA 132
            .|.:...  ....:..|.||:.|||.|...|..|..........|
Human   288 HSSATDDLHHSDRYQTFLRVRANRQTRLNARIGKMKRRKQDEGQV-------------------- 332

  Fly   133 ESSQPTCPVCNHNF--PQSNIQEHVNHCLRQSRRNGQANGERHSSE-DSEDSEEYEEYEWAGQKR 194
                  ||:||...  .:..:..||.|||  |:|.|....|..:.: :.|::..:|||||.||||
Human   333 ------CPLCNRPLAGSEQEMSRHVEHCL--SKREGSCMAEDDAVDIEHENNNRFEEYEWCGQKR 389

  Fly   195 IRVSTLVQGGYSALGLGQRIKYNGSQQAQDDEDEDLNVDEDDTHIYGPTQYGEGDVIPLVNEDTE 259
            ||.:||::||:...|.   |..:|.:  ..|.|.||:||.|||..||..||.|.||||...|:.
Human   390 IRATTLLEGGFRGSGF---IMCSGKE--NPDSDADLDVDGDDTLEYGKPQYTEADVIPCTGEEP- 448

  Fly   260 GNVSEADVTSYVRRLISSSDGPK----PNHSSEATEQEPASTSNVEAPPASEEPSTSRST---RS 317
               .||.....:|..:.:...|.    |..|..|:::.| ||||.|:........|.:::   :.
Human   449 ---GEAKEREALRGAVLNGGPPSTRITPEFSKWASDEMP-STSNGESSKQEAMQKTCKNSDIEKI 509

  Fly   318 TSQNQQQIIESLKAKLRLYEKQ-AQG-KYKCLICIDDYKNPAISVSCWHVHCEQCWLQTLGARKL 380
            |..:.....|:|||::|..|:| ::| :||||||:|.|..|..|:.|||||||:|||:||||:||
Human   510 TEDSAVTTFEALKARVRELERQLSRGDRYKCLICMDSYSMPLTSIQCWHVHCEECWLRTLGAKKL 574

  Fly   381 CPQCNSITTPKDLRRIYL 398
            |||||:||.|.|||||||
Human   575 CPQCNTITAPGDLRRIYL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4813	NP_651088.1	RNF220	22..281	CDD:292548	85/281 (30%)
		zf-C3HC4_2	346..384	CDD:290634	27/38 (71%)
RNF220	XP_005271049.1	RNF220	217..468	CDD:318197	86/282 (30%)
		RING-HC_RNF220	539..579	CDD:319477	29/40 (73%)
		RING-HC finger (C3HC4-type)	540..578	CDD:319477	27/38 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C145561183
eggNOG	1	0.900				E1_28IQH
Hieranoid	1	1.000
Homologene	1	1.000				H10036
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3760
Isobase	1	0.950		0	Normalized mean entropy	S6937
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1583675at2759
OrthoFinder	1	1.000				FOG0004755
OrthoInspector	1	1.000				T1073860
orthoMCL	1	0.900				OOG5_133932
Panther	1	1.100			LDO	PTHR13459
Phylome	1	0.910		0.833	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R5368
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	14	13.740