Protein Alignment cd and Pxdn

DIOPT Version :10

• Sequence 1: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: XP_006515268.1
• Gene: Pxdn / 69675
• MGIID: 1916925
• Length: 1503
• Species: Mus musculus
• Alignment Length: 830
• Identity: 264/830 - (31%)
• Similarity: 384/830 - (46%)
• Gaps: 181/830 - (21%)

  Fly    80 PSFFFVVNGSDSELAPNRPLP------DEPAAEWALQQAALGHHDGAQAVSAGIKALGDREILEE 138
            |.|..:.:....|:..|..||      .|||..|        :.||.|...:     |...|..|
Mouse   550 PVFASIPSDMTVEVGTNVQLPCSSQGEPEPAITW--------NKDGVQVTES-----GKFHISPE 601

  Fly   139 G-LQPNEVNTPSFRHYRSLSTN---------------PEARKLARRG-------YVENQATI--- 177
            | |..|:|.|.....|..::.|               |:   ::|.|       .||..||:
Mouse   602 GFLTINDVGTADAGRYECVARNTIGYASVSMVLSVNVPD---VSRNGDPYVATSIVEAIATVDRA 663

  Fly   178 -----------------DIAKRFNYTKQP---GRSNIGWGPKIV--------------------- 201
                             |:...|.|.:.|   |::..|   :|.
Mouse   664 INSTRTHLFDSRPRSPNDLLALFRYPRDPYTVGQARAG---EIFERTLQLIQEHVQHGLMVDLNG 725

  Fly   202 -------LPDPTVLRL--------------ECD---FNARYRRSTGVCNNKQHPRTYGASMVPYR 242
                   |..|..|.|              .|.   |:.:||...|.|||.||| .:|||:..:.
Mouse   726 TSYHYNDLVSPQYLSLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHP-MWGASLTAFE 789

  Fly   243 RMVSPDYADGIAAPRVSHHGR------LPPARQVSLKIHRSSYET-DSNFTVMLAVFGQFMDHDI 300
            |::...|.:|...||..:..|      ||..|.||..:..:...| |..||.||..:|||:|||:
Mouse   790 RLLKAVYENGFNTPRGINSQRQYNGHVLPMPRLVSTTLIGTEVITPDEQFTHMLMQWGQFLDHDL 854

  Fly   301 TATSLTTSQ----EGESIDCCVAATREQHPECYPVDILPDDPYYKQYNISCMNFVRSAP-APTGR 360
            .:|.:..||    :|:  .|....:.:  |.|:.|.|.|:||..:. ...||.||||:| ..:|.
Mouse   855 DSTVVALSQARFSDGQ--HCSSVCSND--PPCFSVMIPPNDPRVRS-GARCMFFVRSSPVCGSGM 914

  Fly   361 FG-------PRMQLNQATAFIDASVVYGNLEQRQNQLRSFIN--GSLRM-FVTDDGRQLLPISSN 415
            ..       ||.|:||.|::||||.|||:.:.....:|...:  |.||. .|...|:.|||.::.
Mouse   915 TSLLMNSVYPREQINQLTSYIDASNVYGSTDHEARSIRDLASHRGLLRQGIVQRSGKPLLPFATG 979

  Fly   416 PADGCNRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEA 480
            |...|.|.: ......||.:||.||||.|.|||||.||.|.||.:|.:|.:.||||:.:.:|.|.
Mouse   980 PPTECMRDE-NESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIAAELLKLNPHWDGDTVYHET 1043

  Fly   481 RKILGAQMAHITYNEFLPVLLG----KNISEAKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAF 541
            |||:||::.||||..:||.:||    |.:.|.:|             |||.|:..|.|.||.|||
Mouse  1044 RKIVGAEIQHITYRHWLPKILGEVGMKMLGEYRG-------------YDPSVNAGIFNAFATAAF 1095

  Fly   542 RFAHTLL-PGLFNISRD-NSTPEA-IELHKMLFNPFSLWAEHGID---HALMTAANTPVMQV-DR 599
            ||.|||: |.|:.:..: ...|:. :.|||..|:||.:..|.|||   ..|...|..  |:: .:
Mouse  1096 RFGHTLINPLLYRLDENFEPIPQGHVPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGK--MRIPSQ 1158

  Fly   600 FFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLPTVDTWEEMSQAID 664
            ..:.|:|::||     .......|||.::|||||||||||.|..:|.:|.|....|:|::...|.
Mouse  1159 LLNTELTERLF-----SMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAYTFEDLKNEIK 1218

  Fly   665 NATL-DSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQ 728
            :..: :.::::|.|..::|::...:.|..:.|:..||.|.|::|.||.||:.||..|||   .|.
Mouse  1219 SPVIREKLQRLYGSTLNIDLFPALMVEDLVPGSRLGPTLMCLLSTQFRRLRDGDRLWYE---NPG 1280

  Fly   729 KFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHVDCQDL 778
            .|:.|||.::.:||||.|:|.|||.||||::.|. |:.:..:.:..|:|:
Mouse  1281 VFSPAQLTQLKQTSLARILCDNSDNITRVQQDVF-RVAEFPHGYSSCEDI 1329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..762	CDD:460804	217/577 (38%)
Pxdn	XP_006515268.1	leucine-rich repeat	94..112	CDD:275380
		leucine-rich repeat	113..127	CDD:275378
		LRR_8	160..219	CDD:404697
		leucine-rich repeat	161..184	CDD:275378
		leucine-rich repeat	185..208	CDD:275378
		leucine-rich repeat	209..221	CDD:275378
		LRRCT	217..268	CDD:214507
		I-set	271..358	CDD:400151
		Ig strand B	288..292	CDD:409353
		Ig strand C	301..305	CDD:409353
		Ig strand F	339..344	CDD:409353
		Ig strand G	353..356	CDD:409353
		I-set	367..454	CDD:400151
		Ig strand B	384..388	CDD:409353
		Ig strand C	397..401	CDD:409353
		Ig strand E	420..424	CDD:409353
		Ig strand F	434..439	CDD:409353
		Ig strand G	447..450	CDD:409353
		Ig3_Peroxidasin	471..544	CDD:143222
		Ig strand B	475..479	CDD:143222
		Ig strand C	488..492	CDD:143222
		Ig strand E	510..514	CDD:143222
		Ig strand F	524..529	CDD:143222
		Ig strand G	538..541	CDD:143222
		Ig4_Peroxidasin	567..635	CDD:143223	19/80 (24%)
		Ig strand B	567..571	CDD:143223	1/3 (33%)
		Ig strand C	580..584	CDD:143223	2/11 (18%)
		Ig strand E	602..606	CDD:143223	2/3 (67%)
		Ig strand F	616..621	CDD:143223	1/4 (25%)
		Ig strand G	630..633	CDD:143223	0/2 (0%)
		peroxidasin_like	889..1328	CDD:188658	176/464 (38%)
		VWC	1439..1494	CDD:214564