DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and T06D8.10

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_496407.1	Gene:	T06D8.10 / 174717	WormBaseID:	WBGene00011530	Length:	1490	Species:	Caenorhabditis elegans

Alignment Length:	695	Identity:	233/695 - (33%)
Similarity:	333/695 - (47%)	Gaps:	57/695 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 DGAQAVSAGIKALGDREILEEGLQPNEVNTPSFRHYRSLSTNPEARKLARRGYVENQATIDIAKR 182
            :||:.||. |.||    :||        .|........|.|:.:..||......:....||:...
Worm   764 EGAKQVSQ-ISAL----LLE--------TTKLLIKGEGLDTDEQLPKLDTHTLQKILPDIDVTSF 815

  Fly   183 F-NYT---KQPGRSN-IGWGPKIVLPDPTVLRLECDFNARYRRSTGVCNNKQHPRTYGASMVPYR 242
            . |||   .:.|:|: ....||:         |.||...|||...|.|||.:.|. |..|..|.|
Worm   816 VNNYTAFLSEDGQSSQEECSPKM---------LPCDHTTRYRTFNGWCNNLKFPE-YANSFAPLR 870

  Fly   243 RMVSPDYADGIAAPRV-SHHGR-LPPARQVSLKIHRSSYETDSNFTVMLAVFGQFMDHDITATSL 305
            .::.|.|.||..|||. :..|| ||..|:||..:......:...||.|:..|||.:||::|.:.:
Worm   871 HLLPPQYDDGFDAPRTRAKSGRPLPNPRRVSNLVCEDKDVSHVKFTHMVMQFGQLLDHELTHSPV 935

  Fly   306 TTSQEGESIDCCVAATREQHPE-----CYPVDILPDDPY----YKQYNISCMNFVRSAPAPTGRF 361
            ......|.::|    |:...||     |.|:.:..|||:    |......|:.|.||..... ..
Worm   936 ARGPNDEILNC----TKCDSPEKISVHCMPIRVEKDDPFFPTNYPNGEPRCLPFARSLLGQL-NL 995

  Fly   362 GPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSLRMFVTDDGRQLLPISSNPADGCNRVQMT 426
            |.|.||||.||::|.|.:||:.:.....||.|..|.|.......|:.:|| ..|....| |..:.
Worm   996 GYRNQLNQLTAYVDGSAIYGSTKCEAKNLRLFTRGLLNFTDFGHGQMMLP-QGNQEKDC-RSTLE 1058

  Fly   427 RLGKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHI 491
            :....||.:||:|.:....||.||..:.|.||.:|.||...||.|.|:.:::|||:|:.|:|.||
Worm  1059 KRHMPCFVAGDERNSHQPGLTIMHTFFVREHNRIAMQLSALNPQWNDDTVFEEARRIVTAEMQHI 1123

  Fly   492 TYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAFRFAHTLLPGLF---N 553
            |:.||||.::|.::..|:.|:|.|:....  .||...|.||:..||.|||||.|||:..:|   |
Worm  1124 TFAEFLPKIIGLDLLNAQNLVPKKNGYFG--GYDNTCDASISQPFATAAFRFGHTLIRRMFPRMN 1186

  Fly   554 ISRDN-STPEAIELHKMLFNPFSLWAEHGIDHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDR 617
            .:..| |.|..:..|.....|.....:.|:|..||....||.|..||..:..|...||....|
Worm  1187 YNYKNMSEPVDLAQHFGHVGPLYEQEKGGMDSMLMGLLGTPSMAFDRHITDAVRNHLFMRRGE-- 1249

  Fly   618 VPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLPTVDTWEEMSQAIDNATLDSIRQIYESPQDVD 682
             ...|:||:.|||.|.||||:..|...|..|.|.....|:::...:|...::.::.:|||..|||
Worm  1250 -KTSGMDLIVLNILRARDHGVQPYNDLREFCGLRRAVKWDDLKGEMDQDNINILQSLYESVDDVD 1313

  Fly   683 VYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAII 747
            ::.|.:||.||.||:.|..:||::::||.|||..|..:||......|||..||.||.|..||:|.
Worm  1314 LFPGLVSERPLRGALLGTTMSCIIAEQFGRLKKCDRFYYENDNSAAKFTPGQLNEIRKVKLASIF 1378

  Fly   748 CRNSDGITRVREHVMQRLRDGGNPHVDCQDLEGFHFNFEPWSEKQ 792
            |.||..:..::.:|.....:..|..|.|.|:.  ..:...|.|::
Worm  1379 CSNSKYLKTIQPNVFDVTDELTNAQVPCTDIP--QVDLSLWRERK 1421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	199/551 (36%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	147/389 (38%)
T06D8.10	NP_496407.1	An_peroxidase	160..668	CDD:281139
		peroxinectin_like	308..665	CDD:188655
		An_peroxidase	847..1382	CDD:281139	197/547 (36%)
		peroxinectin_like	998..1381	CDD:188655	147/389 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880