DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and epx

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	XP_002933592.2	Gene:	epx / 100496213	XenbaseID:	XB-GENE-6039946	Length:	716	Species:	Xenopus tropicalis

Alignment Length:	743	Identity:	225/743 - (30%)
Similarity:	353/743 - (47%)	Gaps:	109/743 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 ALQQAALGHHDGAQAVSAGI--------KALGD------REILEEGLQPNEVNTPSFRHYRSLST 158
            ::|..|..::||.:.:...:        |.|.|      |.:|:|.|:...|:......|.....
Frog    16 SVQITASSYYDGVEELDNNLILSCTKEAKHLVDIAYKNTRLMLKERLRKRTVSASDLMAYFKQPV 80

  Fly   159 NPEARKLARRGYVENQATIDIAKR--------FNYTKQPGRSNIGWGPKIVLPDPTVLRLE-CDF 214
            ......:....|:.....: ::|:        ||.|.....:.|          .|:.:|. |.:
Frog    81 AGSRNAIRAADYMGTTLQL-LSKKLQPFHHRPFNITDLLTETQI----------DTIYKLTGCAY 134

  Fly   215 --------NARYRRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPR-----VSHHG-RLP 265
                    .:.||..||.|||:::| ..|||...:.|::...|.||::.||     :..:| .||
Frog   135 QHLPRACQESTYRTITGECNNRKNP-ILGASNTGFTRLLPAVYEDGVSLPRGWTENLPINGFPLP 198

  Fly   266 PARQVSLKIHRSSYET---DSNFTVMLAVFGQFMDHDITATSLTTSQEG--ESIDCCVAATREQH 325
            .||.||.:|.|...|.   |....::...:||:.|||:..:..|.::..  |.|||..:..::
Frog   199 LARAVSNEIVRFPNENLTLDQGRALIFMQWGQWTDHDLDLSPETPARSTFLEGIDCDTSCAKQ-- 261

  Fly   326 PECYPVDILPDDPYYKQYNISCMNFVRSAPAPTGRFGPRMQLNQATAFIDASVVYGN-------L 383
            |.|:|:.|.|:||..:..: .|:...||:|..|.....|.|:|..|:|:|.|.|||:       |
Frog   262 PPCFPLKIPPNDPRIRNQS-DCIPLFRSSPVCTPGSPVREQINVLTSFLDGSQVYGSDWPLAVKL 325

  Fly   384 EQRQNQLRSFINGSLRMFVTDDGRQLLPISSNPADGC---NRVQMTRLGKYCFESGDDRANENLL 445
            ....|||...   ::....||:|...||..:...|.|   ||..    |..||..||.|.:|...
Frog   326 RNNTNQLGLM---AINQKFTDNGLPFLPFETAEEDFCVLTNRSS----GIPCFLGGDPRVSEQPG 383

  Fly   446 LTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKG 510
            ||:.|.|:.|.||.:|.:|:|.||.|..|.||||||||:|..:..|||.::||:|||   ||...
Frog   384 LTAFHTLFVRAHNNIATRLRELNPRWSGETLYQEARKIVGGILQKITYKDWLPLLLG---SEMAT 445

  Fly   511 LLPAKHNLNAPDTYDPEVDPSIANCFAAAAFRFAHTLL-PGLFNIS---RDNSTPEAIELHKMLF 571
            :|||..      :|:..|||.:||.| ...||..|||: |.::.::   |..:....:.||...|
Frog   446 VLPAYR------SYNENVDPRVANVF-TVVFRMGHTLIQPFIYRLADGYRPLNPEPRVPLHMTFF 503

  Fly   572 NPFSLWAEHGIDHAL--MTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGR 634
            |.:.:..|.|||..|  :.|....:.:.::....|:.::||  ....|:   ||||.::|:||||
Frog   504 NSWRVVREGGIDPLLRGLMANRAKLNRQNQLVVDELRERLF--VLFKRI---GLDLTAINMQRGR 563

  Fly   635 DHGIPSYPVFRRHCRLPTVDTWEEMSQAIDNATL-DSIRQIYESPQDVDVYTGALSEPPLDGAIF 698
            :||:|.|..:||.|.|......:|::..::|..| :...::|.:|:::|::.|.::|..:.....
Frog   564 EHGLPGYNAWRRFCGLSAPRNVDELAAVLNNRGLAEKFVKLYGTPENIDIWVGGVAESLVRNGRI 628

  Fly   699 GPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVM- 762
            |.||:|::.:||.|.:.||..:||:   |..||.||.|.|.:.:||.:||.|:. ||.|..:|.
Frog   629 GKLLTCLIGNQFRRARDGDRFYYEQ---PTVFTNAQRASIERVTLARVICDNTK-ITEVPRNVFL 689

  Fly   763 --QRLRDGGNPHVDCQDLEGFHFNFEPW 788
              |..||    ...|..:.....|  ||
Frog   690 GNQYPRD----FFPCSRIPTLDLN--PW 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	192/564 (34%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	141/402 (35%)
epx	XP_002933592.2	myeloperoxidase_like	288..697	CDD:188656	152/438 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010